Biome

What happens to our gut flora when we switch from a more animal-based diet to a more plant-based diet? Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ Here’s the link to the TMAO video I showed: Carnitine, Choline, Cancer, and Cholesterol: The TMAO Connection (http://nutritionfacts.org/video/carnitine-choline-cancer-and-cholesterol-the-tmao-connection/). An update on TMAO in How Our Gut Bacteria Can Use Eggs to Accelerate Cancer (http://nutritionfacts.org/video/How-Our-Gut-Bacteria-Can-Use-Eggs-to-Accelerate-Cancer) and Egg Industry Response to Choline & TMAO (http://nutritionfacts.org/video/egg-industry-response-to-choline-and-tmao/). More on keeping our gut bugs happy here: • Microbiome: The Inside Story (http://nutritionfacts.org/video/microbiome-the-inside-story/) • Prebiotics: Tending our Inner Garden (http://nutritionfacts.org/video/prebiotics-tending-our-inner-garden/) • What’s your Gut Microbiome Enterotype? (http://nutritionfacts.org/video/whats-your-gut-microbiome-enterotype/) • How to Change your Enterotype (http://nutritionfacts.org/video/how-to-change-your-enterotype/) • Paleopoo: What We Can Learn from Fossilized Feces (http://nutritionfacts.org/video/paleopoo-what-we-can-learn-from-fossilized-feces/) • Gut Dysbiosis: Starving Our Microbial Self (http://nutritionfacts.org/video/gut-dysbiosis-starving-microbial-self/) • How to Develop a Healthy Gut Ecosystem (http://nutritionfacts.org/video/How-to-Develop-a-Healthy-Gut-Ecosystem) • How to Become a Fecal Transplant Super Donor (http://nutritionfacts.org/video/How-to-Become-a-Fecal-Transplant-Super-Donor) Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/microbiome-we-are-what-they-eat and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/microbiome-we-are-what-they-eat. You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Image Credit: Shannon Coffey / Flickr Icons created by Graham Jefferson, Alexander Skowalsky, Gorkem Oner, Maxim Kulikov, and Artem Kovyazin from the Noun Project. https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

Scientists have developed a pioneering new treatment to prevent bacterial skin infections, which could be used in the battle against 'superbugs', such as MRSA.

A new review looks at the evidence behind the effectiveness of complementary or alternative therapies-including probiotics, prebiotics, synbiotics, fiber, and herbal medicinal products-for the treatment of bowel disorders such as irritable bowel syndrome (IBS), functional constipation, and ulcerative colitis.

A connection between the bacteria living in the gut and immunological disorders such as multiple sclerosis have long been suspected, but for the first time, researchers have detected clear evidence of changes that tie the two together. Investigators have found that people with multiple sclerosis have different patterns of gut microorganisms than those of their healthy counterparts. In addition, patients receiving treatment for MS have different patterns than untreated patients.

In a recent study, children with multiple sclerosis had differences in the abundance of specific gut bacteria than children without the disease. Certain types of bacteria were either more or less abundant in children with multiple sclerosis. In particular, there was an association between multiple sclerosis and an increase in gut bacteria that have been linked to inflammation and a decrease in gut bacteria that are considered anti-inflammatory.

Background Late onset sepsis (LOS) in preterm infants is associated with considerable morbidity and mortality. While studies have implicated gut bacteria in the aetiology of the disease, functional analysis and mechanistic insights are generally lacking. We performed temporal bacterial (n = 613) and metabolomic (n = 63) profiling on extensively sampled stool from 7 infants with LOS and 28 matched healthy (no LOS or NEC) controls. Results The bacteria isolated in diagnostic blood culture usually corresponded to the dominant bacterial genera in the gut microbiome. Longitudinal changes were monitored based on preterm gut community types (PGCTs), where control infants had an increased number of PGCTs compared to LOS infants (P = 0.011). PGCT 6, characterised by Bifidobacteria dominance, was only present in control infants. Metabolite profiles differed between LOS and control infants at diagnosis and 7 days later, but not 7 days prior to diagnosis. Bifidobacteria was positively correlated with control metabolites, including raffinose, sucrose, and acetic acid. Conclusions Using multi-omic analysis, we show that the gut microbiome is involved in the pathogenesis of LOS. While the causative agent of LOS varies, it is usually abundant in the gut. Bifidobacteria dominance was associated with control infants, and the presence of this organism may directly protect, or act as a marker for protection, against gut epithelial translocation. While the metabolomic data is preliminary, the findings support that gut development and protection in preterm infants is associated with increased in prebiotic oligosaccharides (e.g. raffinose) and the growth of beneficial bacteria (e.g. Bifidobacterium).

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Our bodies are having a conversation with our microbiome that may be affecting our mental health — for better or worse.

Seven dates a day for three weeks are put to the test in a randomized controlled trial. Subscribe to NutritionFacts.org’s free newsletter to receive our B12 infographic that covers the latest research takeaways and Dr. Greger’s updated recommendations: https://nutritionfacts.org/subscribe/ Here’s those remarkable labor and delivery videos: Best Food for Late Pregnancy (http://nutritionfacts.org/video/best-food-for-late-pregnancy) and Best Food for Labor and Delivery (http://nutritionfacts.org/video/best-food-for-labor-and-delivery). And here’s some recipes! Date Syrup (https://nutritionfacts.org/recipe/date-syrup/) and a Balsamic Date Glaze (https://nutritionfacts.org/recipe/balsamic-date-glaze/). But what about all the sugar in dates? See: If Fructose is Bad, What About Fruit? (https://nutritionfacts.org/video/if-fructose-is-bad-what-about-fruit/). The other video I referenced to is Stool pH and Colon Cancer (https://nutritionfacts.org/video/stool-ph-and-colon-cancer/). I did a month-long video series on mammograms. What about colonoscopies? See: Should We All Get Colonoscopies Starting at Age 50? (https://nutritionfacts.org/video/should-we-all-get-colonoscopies-starting-at-age-50). Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/video/benefit-of-dates-for-colon-health and someone on the NutritionFacts.org team will try to answer it. Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at http://nutritionfacts.org/video/benefit-of-dates-for-colon-health. You’ll also find a transcript and acknowledgments for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics. If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscription_center?add_user=nutritionfactsorg Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution! -Michael Greger, MD FACLM Captions for this video are available in several languages. To find yours, click on the settings wheel on the lower-right of the video and then "Subtitles/CC." Do you have feedback about the translations in this video? Please share it here along with the title of the video and language: https://nutritionfacts.zendesk.com/hc/requests/new To view the subtitles in transcript format, click on the ellipsis button below the video, choose "Open transcript", and select the language you'd like to view them in. Image credit: ferumov / Adobe Stock Photos https://NutritionFacts.org • Subscribe: https://nutritionfacts.org/subscribe • Donate: https://nutritionfacts.org/donate • Podcast : https://nutritionfacts.org/audio • Facebook: www.facebook.com/NutritionFacts.org • Twitter: www.twitter.com/nutrition_facts • Instagram: www.instagram.com/nutrition_facts_org • Books (including the NEW How Not to Diet Cookbook): https://nutritionfacts.org/books • Shop: https://drgreger.org

The microbiome has emerged as a major determinant of the functioning of host organisms, affecting both health and disease. Here, Han et al. use the wo…

Multiple Sclerosis (MS), is a common autoimmune disease that affects the central nervous system. Currently, there is no cure for MS, and most treatments involve the use of immunosuppressive drugs that can have adverse effects or increased toxicity. Cannabis, commonly known as marijuana, is a product of the Cannabis sativa , and for several centuries has been used as an alternative medicine in many cultures. Cannabis sativa produces over 421 chemical compounds, including about 80 terpenophenols named phytocannabinoids, and include both psychotropic THC and non-psychoactive CBD. In the currently study, we show that a combination therapy using THC and CBD results in amelioration of EAE, an animal model of MS, by reducing hind limb paralysis, decreasing immune cellular infiltration into the brain, and mitigating the presence of inflammatory biomarkers, including gram negative bacteria-associated lipopolysaccharide (LPS). Interestingly, the gut microbiome plays an important role in immune function and studies have shown that it is altered significantly in MS patients. Inasmuch, we performed 16S rRNA sequencing on experimental groups to investigate the gut microbiome composition after using a combination of THC and CBD compared to disease controls. Interestingly, we found that EAE mice showed increase in the mucin degrading bacterial species, Akkermansia municiphila , which was significantly reduced in disease mice treated with THC+CBD. Collectively, our data suggests that THC+CBD can ameliorate EAE by preventing accumulation of mucin-degrading bacteria that would lead to increased gut microbial dysbiosis.

Antibiotics may be linked to a serious disruption in brain function, called delirium, and other brain problems, more than previously thought, according to a new article. Delirium causes mental confusion that may be accompanied by hallucinations and agitation. Medications are often the cause of delirium, but antibiotics are not necessarily the first medications doctors may suspect.

Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the “gut-brain axis” for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract.

In one of the largest microbiota studies conducted in humans, researchers have shown a potential link between healthy aging and a healthy gut.

Research indicates that the ancient spice turmeric may help to mitigate the growing threat of antibiotic resistant infections that the CDC estimates will take 23,000 U.S. lives each year.

Bacteria that live in the gut have been used to reverse obesity and Type-2 diabetes, animal studies show.