Exosomes

Take a quick tour through the last 20 years of regenerative medicine, bone marrow transplantation, amniotic fluid exosomes and purified exosome derived growth factors. The future of stem cells is cell free, and Kimera Labs has been providing purified exosomes for that goal since 2014, pioneering what will become the penicillin of our generation. Here's how we do it.

Exosomes released from different types of host cells have different biological effects. We report that exosomes released from retinal astroglial cells (RACs) suppress retinal vessel leakage and inhibit choroidal neovascularization (CNV) in a laser-induced ...

Kimera Labs is a manufacturer of exosome products and specializes in the production of mesenchymal stem cell exosomes.

Difficult-to-treat, chronic wounds in preclinical models healed with normal scar-free skin after treatment with an acellular product. Derived from platelets, the purified exosomal product, known as PEP, was used to deliver healing messages into cells of preclinical animal models of ischemic wounds. The research team documented restoration of skin integrity, hair follicles, sweat glands, skin oils and normal hydration.

Exosomes are nanometer-sized vesicles that are released by cells in a controlled fashion and mediate a plethora of extra- and intercellular activities. Some key functions of exosomes include cell-cell communication, immune modulation, extracellular matrix ...

Mesenchymal stem cells (MSCs) were, due to their immunomodulatory and pro-angiogenic characteristics, extensively explored as new therapeutic agents in cell-based therapy of uveitis, glaucoma, retinal and ocular surface diseases.Since it was recently revealed that exosomes play an important role in …

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