Covid + Kids

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Characterizing Long COVID in Children and Adolescents
Characterizing Long COVID in Children and Adolescents
This observational cohort study examines the symptoms experienced by children after SARS-CoV-2 infection and how these symptoms differ by age (6-11 years vs 12-17 years).
Characterizing Long COVID in Children and Adolescents
Long COVID Rates in Kids Revised Upward: What to Know
Long COVID Rates in Kids Revised Upward: What to Know
Fresh data show that long COVID in children is more common than previously thought, while symptoms — particularly gastrointestinal — can differ from adults'.
Long COVID Rates in Kids Revised Upward: What to Know
Neurodevelopmental delay in children exposed to maternal SARS-CoV-2 in-utero
Neurodevelopmental delay in children exposed to maternal SARS-CoV-2 in-utero
Around 11.6% of toddlers born to mothers with lab-confirmed SARS-CoV-2 infection during pregnancy showed cognitive, motor, or language problems indicative of neurodevelopmental delays. By comparison, only two of 128 unexposed controls — 1.6% — showed such issues.
Neurodevelopmental delay in children exposed to maternal SARS-CoV-2 in-utero
The long-term neurodevelopmental outcomes of toddlers with SARS-CoV-2 infection in the neonatal period: a prospective observational study - Italian Journal of Pediatrics
The long-term neurodevelopmental outcomes of toddlers with SARS-CoV-2 infection in the neonatal period: a prospective observational study - Italian Journal of Pediatrics
Background The effect of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) virus in the neonatal period on developing brain is still unknown. This study aims to investigate the long-term neurodevelopmental outcomes of newborns exposed to SARS-CoV-2 & Delta variant. Methods At a tertiary referral center, a prospective observational cohort research was carried out. All babies who were equal to or more than 34 gestational weeks gestation and were admitted to the NICU between January 2021 and January 2022 due to SARS-CoV-2 infection (Delta - or Delta +) were included in the study. Infants who were hospitalized for non-SARS-CoV-2 reasons at similar dates and who had no history of invasive mechanical ventilation were incorporated as a control group using a 2:1 gender and gestational age match. Thirty infants were assigned to the study group and sixty newborns to the control group based on the sample size calculation. These toddlers’ neurodevelopment was evaluated between the ages of 18 and 24 months using the Bayley-II scale. Results We enrolled 90 infants. SARS-CoV-2-positive infants had poorer psychomotor development index (PDI) scores and significantly greater mildly delayed performances (MDPs) at 18–24 months (PDI p = 0.05, MDPs p = 0.03, respectively). Delta variant showed statistically significant lower MDI and PDI scores (MDI p=0.03, PDI p=0.03, respectively). A smaller head circumference of SARS-CoV-2-positive toddlers was detected in the first year (p
The long-term neurodevelopmental outcomes of toddlers with SARS-CoV-2 infection in the neonatal period: a prospective observational study - Italian Journal of Pediatrics
Cardiopulmonary Exercise Testing in Children With Long... : The Pediatric Infectious Disease Journal
Cardiopulmonary Exercise Testing in Children With Long... : The Pediatric Infectious Disease Journal
VID (LC), while the evidence about its role in children with this condition is scarce. Methods: Prospective, case-controlled observational study. Children with LC and a control group of healthy children underwent CPET. CPET findings were compared within the 2 groups, and within the LC groups according to main clusters of persisting symptoms. Results: Sixty-one children with LC and 29 healthy controls were included. Overall, 90.2% of LC patients (55 of 61) had a pathologic test vs 10.3% (3/29) of the healthy control. Children with LC presented a statistically significant higher probability of having abnormal values of peak VO2 (P = 0.001), AT% pred (P
Cardiopulmonary Exercise Testing in Children With Long... : The Pediatric Infectious Disease Journal
Scientists alarmed by COVID’s diabetes link, particularly in children
Scientists alarmed by COVID’s diabetes link, particularly in children

"When Ziyad Al-Aly’s research team told him how often diabetes appeared to strike Covid-19 survivors, he thought the data must be wrong, so he asked his five colleagues to crunch the numbers again.

Weeks later, they returned the same findings after sifting through millions of patient records. By then Al-Aly had also gone digging into the scientific literature and was starting to come to terms with an alarming reality: Covid-19 isn’t just deadlier for people with diabetes, it’s also triggering the metabolic disease in many who didn’t previously have it."

Scientists alarmed by COVID’s diabetes link, particularly in children
Effect of COVID-19 infection on psychological aspects of pre-schooler children: a cross-sectional study - Middle East Current Psychiatry
Effect of COVID-19 infection on psychological aspects of pre-schooler children: a cross-sectional study - Middle East Current Psychiatry
Background Coronavirus disease 2019 (COVID-19) had a tremendous effect on individual’s lives worldwide. The pandemic’s significant socioecological impact is one of the many burdens children confront in the current crises. As a result, this study was designed to determine the psychological impacts of the COVID-19 pandemic on preschoolers, particularly the consequences of COVID-19 infection. This study involved 138 children aged 2–5.11 years old who were classified into two groups based on their COVID-19 infection history, which was documented via a PCR test. All participants were assessed by the Socioeconomic Scale and The Children’s Behavior Checklist (CBCL). Results COVID-19 infection was found in 21.7% of the children who participated in this study. Furthermore, children with COVID-19 had a higher percentage of clinical rating on the CBCL Profile of DSM-5 scales for affective problems (13.3 vs. 7.4%), anxiety problems (13.3 vs. 9.3%), pervasive developmental problems (20 vs. 13%), and oppositional defiant problems (6.7 vs. 5.6%) than children without COVID-19. Anxiety and somatic problems had a positive correlation with the impact of the COVID-19 pandemic on the lives of children. Conclusions Children infected with COVID-19 were more likely to have psychological issues, such as affective disorders, anxiety problems, pervasive developmental problems, and oppositional defiant problems. These psychological issues had a relationship with the impact of the COVID-19 pandemic on the lives of children.
Effect of COVID-19 infection on psychological aspects of pre-schooler children: a cross-sectional study - Middle East Current Psychiatry
Life as a young person with long COVID: “You go through so many phases of up and down, it’s like being on a rollercoaster forever”
Life as a young person with long COVID: “You go through so many phases of up and down, it’s like being on a rollercoaster forever”
As young people across Europe go back to school, we speak to 16-year-old Kitty McFarland about the daily difficulties of living with post COVID-19 condition (also known as long COVID) and the steps schools can take to protect their students from its symptoms. In March 2020 Kitty McFarland was a fit and healthy 14-year-old. She enjoyed ballet, paddleboarding, running and netball. Then she contracted COVID-19. Kitty remembers experiencing only a cough and flu-like fever, but her mother Sammie, who became ill with COVID-19 at around the same time, mentioned a terrifying moment when her daughter became unresponsive. Fortunately, these severe symptoms subsided after a few days and her health appeared to improve. About a month later the pair attempted some very light exercise, but the relapse Kitty suffered left her bedbound for the next eight months.“I mainly felt dizzy and exhausted. I would faint a lot and get heart palpitations; I could be just sitting around, and my heart would suddenly leap to 190 beats a minute,” says Kitty. She also developed a gluten intolerance and acute abdominal pain that caused her to faint and required several hospital stays.“Sometimes I needed help to eat all my food; at other times, I couldn’t physically lift a glass because I was so weak, which is hard to admit when you were used to being strong and active,” she recalls. Visual disturbances and brain fog meant that even watching TV or trying to text left her feeling nauseated and exhausted. During this time her father Scott had to care for Kitty and her mother as they were both struggling with long COVID symptoms. A condition not recognized at the timeUnfortunately, in the early days of the pandemic, due to limited understanding of the effects of COVID-19, medical staff could not provide Kitty and her mother with any answers to their health problems, and the advice they were given – to be more active – only risked making their condition worse.To this day Kitty is still struggling because of the effects of long COVID. “Sometimes I find it hard to speak. My brain feels very blurred and I can’t think of a sentence. I stutter a lot. Every day is different. Sometimes I’ll be fatigued and dizzy, sometimes I feel brain fog, but I can walk around with it. Sometimes, if I’m doing well, we can go out for walks, but then the next day I could be back in bed. You go through so many phases of up and down, it’s like being on a rollercoaster forever.” Disrupted education Kitty’s illness forced her to take a long break from school. Online lessons were challenging, and the pressure of trying to complete homework led to further relapses. When in-person education resumed, the effort of trying to cope with the busy school day set her health even further back. Eventually, her family arranged for her to be homeschooled in the lead-up to her exams.“I had an examiner come to my house, which made it a lot easier. I could just go back to bed as soon as I’d taken an exam, which really helped.” The way forward Kitty and her mother manage their illness with a combination of medication and careful pacing of their activities, but they are frustrated by the lack of progress in understanding and recognition of the condition. In addition to more scientific research into long COVID, Kitty would like more educational flexibility for young people suffering from long COVID – for example, in-person tutors who could work with those experiencing fatigue and vision problems.She’d also like to see better understanding of the condition from her peers and teachers.“Kids think, ‘Oh, I won’t get it. I’m younger, I’ve got a healthier immune system.’ But it doesn’t work like that. My mum and I were very sporty. We didn’t have any underlying health conditions,” she says.Her mother Sammie, who went on to found Long COVID Kids, an international charity based in the United Kingdom, voices concern about the lack of recognition for long COVID in young people: “We hear stories from families about children resuming education after COVID-19 with increased allergies or ongoing headaches, nausea or stomach upsets, but their parents are sending them back to school because they don’t know it’s long COVID. Those children are being asked to continue with their normal activities and are not being given the time to rest. It’s not the families’ fault. It’s a lack of education and awareness that’s the issue.”In addition to calling on schools to make adjustments for students with long COVID, she is keen to see measures introduced to improve air quality in educational establishments and more mask-wearing to prevent infections.“If we don’t do that, then we will have an entire generation of children who are likely to be at risk of learning to live with disability. We’re now seeing children who are developing long COVID after reinfection, when they didn’t develop it after their first, second or third infection. With the numbers of repeat infections, this is deeply concerning. Long COVID Kids has been calling for biomedical research and a focus on prevention.”Increasing recognition, research and rehabilitation for post COVID-19 conditionThe scale of post COVID-19 condition and the long-term burden it is likely to have on health systems is only starting to become evident. Studies show that approximately 10–20% of individuals who contracted COVID-19 may experience continued symptoms for weeks, months or even years after their original infection, equating to millions of people worldwide.To date, post COVID-19 condition is not well understood in children and young people and more research is needed, particularly in resource-limited countries, to understand its clinical characteristics, frequency and the risk factors that lead some juvenile populations to experience groupings of persistent symptoms.WHO/Europe is in the process of partnering with Long COVID Europe, a network of patient-led associations that has been gathering information on the condition and sharing it with interested stakeholders since its founding last year.WHO/Europe has also been working with patient groups to define priority areas where action is needed. It is now calling upon governments and authorities to focus attention on long COVID and its sufferers through greater:recognition: all services must be adequately equipped, and no patient should be left alone or have to struggle to navigate a system that is not prepared or not able to recognize this very debilitating condition;research and reporting: data gathering and reporting of cases and well-coordinated research with full participation of patients are needed to advance understanding of the prevalence, causes and costs of long COVID; andrehabilitation: this cost–effective intervention is an investment in building back healthy and productive societies.
Life as a young person with long COVID: “You go through so many phases of up and down, it’s like being on a rollercoaster forever”
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
CYP have a fluctuating experience of cognitive impairment by 12-months post SARS-CoV-2-infection. Cognitive impairment is consistently correlated with poorer sleep, behavioural and emotional functioning over a 12-month period. Clinicians should be aware of cognitive impairment post-infection and its …
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed