COVID-19 linked to long-term risk for autoimmune, autoinflammatory disease
“COVID-19 linked to long-term risk for autoimmune, autoinflammatory disease”
COVID-19 linked to long-term risk for autoimmune, autoinflammatory disease
POTS and COVID-19: What is the link?
“there may be a link between COVID-19 and postural orthostatic tachycardia syndrome (POTS). One theory explains that the virus may cause the immune system to attack itself.”
there may be a link between COVID-19 and postural orthostatic tachycardia syndrome (POTS). One theory explains that the virus may cause the immune system to attack itself.
Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long COVID
Key finding: Long COVID linked to new autoimmune disorders like lupus, myasthenia gravis.
COVID-19 worsens Autoimmune Diseases! Study reveals 30 percent spike in antinuclear antibody positivity
“new study has revealed shocking details about the long-term health impacts of COVID-19, particularly concerning autoimmune diseases. The study conducted by Metropolis analyzed data from over 1.2 lakh cases, comparing two critical periods—2019 (pre-COVID) and 2022 (post-COVID). The findings revealed a striking 30% increase in the prevalence of Antinuclear Antibody (ANA) positivity in the Indian population, indicating how the immune system may, in some cases, turn against the body’s own tissues following a COVID-19 infection.”
Multi-ancestry GWAS of Long COVID identifies immune-related loci and etiological links to chronic fatigue syndrome, fibromyalgia and depression
“Using consented and genotyped data from 23andMe adult research participants, we conducted the largest multi-ancestry meta-analysis of genome-wide association studies of Long COVID across European (42,899 cases, 94,721 controls), Latinx (8,631 cases, 20,351 controls), and African-American (2,234 cases, 5,596 controls) genetic ancestry groups. GWAS of Long COVID identified three genome-wide significant loci (HLA-DQA1 and HLA-DQB, ABO, BPTF:KPAN2:C17orf58). Functional analysis of these genes points to underlying immune and thrombo-inflammatory mechanisms.”
Using consented and genotyped data from 23andMe adult research participants, we conducted the largest multi-ancestry meta-analysis of genome-wide association studies of Long COVID across European (42,899 cases, 94,721 controls), Latinx (8,631 cases, 20,351 controls), and African-American (2,234 cases, 5,596 controls) genetic ancestry groups. GWAS of Long COVID identified three genome-wide significant loci (HLA-DQA1 and HLA-DQB, ABO, BPTF:KPAN2:C17orf58). Functional analysis of these genes points to underlying immune and thrombo-inflammatory mechanisms.
Autoimmune Disease and COVID-19: a Complicated Relationship, Say Colorado Experts
“It is apparent that people with autoimmune disease have problems fighting off COVID. They are at higher risk for catching COVID in the first place and at higher risk for more severe COVID because their immune system can’t handle it once it occurs.”