Understanding autoimmune response after SARS-CoV-2 infection and the pathogenesis/mechanisms of long COVID
Key finding: Long COVID linked to new autoimmune disorders like lupus, myasthenia gravis.
SARS-CoV-2 spike aggravates lupus nephritis and lung fibrosis in systemic lupus erythematosus
South Korea study suggests SarsCov2 accelerates progression of Lupus.
COVID-19 spike protein worsens lupus, increasing autoantibodies, kidney damage, and lung fibrosis.
Mild Primary or Breakthrough SARS-CoV-2 Infection Promotes Autoantibody Production in Individuals with and without Neuro-PASC | ImmunoHorizons | American Association of Immunologists
“In this study, we demonstrate that mild SARS-CoV-2 infection increases autoantibodies associated with rheumatic autoimmune diseases and diabetes in most individuals, regardless of vaccination status prior to infection…
…These data highlight the need for additional strategies to decrease the spread of SARS-CoV-2 such as the development of vaccines that can prevent infection rather than decrease severity of acute disease alone.”