Are We Screwed? Bone Marrow Destruction - Covid F’d us?
Covid and Bones
Osteonecrosis as a manifestation of Long-COVID Syndrome: a systematic review
COVID-19 can cause osteonecrosis, leading to joint pain. Symptoms often appear 16 weeks post-infection.
Megakaryocytes Under Siege: Another Hidden Culprit Behind COVID-19 Complications
Megakaryocytes Under Siege: Another Hidden Culprit Behind COVID-19 Complications
Daniel Brittain Dugger on Twitter
Analysis thread on Twitter SARS-Cov-2 causes osteoporosis as a consequence of monocyte derived macrophages differentiating into osteoclasts, which participate in bone remodeling. This has been known since this article.
COVID-19 may damage bone marrow immune cells; another reinfection reported
"In COVID-19 patients with more severe disease, monocytes do not function properly...It was not yet clear whether the monocytes are being released from the bone marrow in an altered state or whether the alterations happen after monocytes enter the blood"
Long COVID-19: Causes of Bone Death and its Treatments - News18
One of the conditions reported by doctors as part of Long COVID-19 was avascular necrosis (AVN) or bone death...caused by temporary or permanent loss of blood supply to a bone. As the blood supply is cut off, bone tissue dies, causing the bone to collapse.
IU researchers study long-term effects of COVID-19 on bone growth
"SARS-CoV-2 can cause quick and significant bone loss—even when infections appear to be mild..."
Mice infected with the virus: Lost 25% of bone mass within 2 weeks Had 63% increase in osteoclasts--cells that cause bone to break down.
COVID-19 illness and treatment decrease bone mineral density of surviving hospitalized patients - PubMed
Bone mineral density (BMD) decreased by 8.6% from diagnosis of covid to follow-up. Osteoporosis ratio increased two-fold.