A new paper in Cell, āPioneering discovery and therapeutics at the brain-vascular-immune interface,ā describes COVID-19 as a neurological disease alongside multiple sclerosis, Alzheimerās, stroke and traumatic brain injury.
āCOVID-19 can accelerate progression of dementia and induce BBB disruption and inflammatory blood clots causally linked with neuroinflammation and neuronal loss.8 In neurodevelopmental disorders, prematurity and perinatal hypoxia that trigger brain hemorrhage and BBB disruption are risk factors for cerebral palsy, intellectual disability, and autism. Collectively, these risk factors highlight the interconnected vascular and immune triggers of neurological diseases.ā