Covid and Brain Damage

Covid and Brain Damage

#Brain #brain "#brain fog"
Systemic increase of AMPA receptors associated with cognitive impairment of long COVID | Brain Communications | Oxford Academic
Systemic increase of AMPA receptors associated with cognitive impairment of long COVID | Brain Communications | Oxford Academic
“Long COVID primarily presents with persistent cognitive impairment (Cog-LC), imposing a substantial and lasting global burden. Even after the pandemic, there remains a critical global need for diagnostic and therapeutic strategies targeting Cog-LC.”
Long COVID primarily presents with persistent cognitive impairment (Cog-LC), imposing a substantial and lasting global burden. Even after the pandemic, there remains a critical global need for diagnostic and therapeutic strategies targeting Cog-LC.
·academic.oup.com·
Systemic increase of AMPA receptors associated with cognitive impairment of long COVID | Brain Communications | Oxford Academic
New study reveals molecular basis of Long COVID brain fog
New study reveals molecular basis of Long COVID brain fog
“the researchers found a notable and widespread increase in the density of AMPARs across the brains of patients. This elevated receptor density was directly correlated with the severity of their cognitive impairment, suggesting a clear link between these molecular changes and the symptoms. Additionally, the concentrations of various inflammatory markers were also correlated with AMPAR levels, indicating a possible interaction between inflammation and receptor expression.”
·news-medical.net·
New study reveals molecular basis of Long COVID brain fog
Human challenge study reveals lasting cognitive decline after mild COVID-19
Human challenge study reveals lasting cognitive decline after mild COVID-19

“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
·news-medical.net·
Human challenge study reveals lasting cognitive decline after mild COVID-19
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
“A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.”
A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.
·medicalxpress.com·
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
Vaccination Does Not Impact Long COVID Neurological Symptoms
Vaccination Does Not Impact Long COVID Neurological Symptoms
“Vaccination prior to COVID-19 infection does not significantly affect neurological symptoms in patients with postacute sequelae of SARS-CoV-2 infection, according to a study published online Jan. 7 in Brain Communications”
Vaccination prior to COVID-19 infection does not significantly affect neurological symptoms in patients with postacute sequelae of SARS-CoV-2 infection, according to a study published online Jan. 7 in Brain Communications.Shreya Mukherjee, from the Northwestern University Feinb
·healthday.com·
Vaccination Does Not Impact Long COVID Neurological Symptoms
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
·x.com·
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle‐Age Adults
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle‐Age Adults
“Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults”
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults
·onlinelibrary.wiley.com·
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle‐Age Adults
SARS-CoV-2 Invasion and Pathological Links to Prion Disease
SARS-CoV-2 Invasion and Pathological Links to Prion Disease

Nearly half of those infected with SARS-CoV-2 experience long-term neurological problems, including brain fog and memory issues.

An infection may accelerate or exacerbate prion diseases like Creutzfeldt–Jakob disease, leading to rapid neurodegeneration.

·mdpi.com·
SARS-CoV-2 Invasion and Pathological Links to Prion Disease
COVID survivors may develop dementia
COVID survivors may develop dementia

“COVID-19 survivors show signs of significant cognitive deficits which could become dementia even a year after having the virus.. The team [in India] found that more than 80% of people tested reported at least one of four symptoms – depression, anxiety, stress and insomnia – ranging from mild to severe.. At least 6.1% of the patients were diagnosed with mild cognitive impairment and 4% developed dementia. More than 60% of the patients experienced a loss of taste and smell during the active phase of the infection. This could alter the function of brain areas linked to cognitive ability and emotional well-being.."

COVID-19 survivors show signs of significant cognitive deficits which could become dementia even a year after having the virus1. They also have an increased risk of depression, anxiety and disrupted sleep.
·nature.com·
COVID survivors may develop dementia
Advanced brain fMRI showed low glutathione : r/covidlonghaulers
Advanced brain fMRI showed low glutathione : r/covidlonghaulers

“Hey all. I thought I would just throw this out there. I had an advanced brain fMRI that was able to show a bunch of brain biomarkers. The only significant finding was that I had low brain glutathione. I was at .56 mM and the normal range is 1-2 mM. He told me this is a large deficiency.

He said this would usually indicate CFS, brain fog, and low energy.”

·reddit.com·
Advanced brain fMRI showed low glutathione : r/covidlonghaulers
Whoopi Goldberg Commiserates With Fellow-Covid Sufferer Joe Biden: “Sometimes I Go For A Word And It’s Not There”
Whoopi Goldberg Commiserates With Fellow-Covid Sufferer Joe Biden: “Sometimes I Go For A Word And It’s Not There”

Whoopi Goldberg, who just had her 4th COVID infection, joked about her post infection brain damage on TV.

“I’m just getting over COVID – again – and I can barely remember anybody’s name. There are times when I go for a word and it’s not there.”

·deadline.com·
Whoopi Goldberg Commiserates With Fellow-Covid Sufferer Joe Biden: “Sometimes I Go For A Word And It’s Not There”
Covid Brain
Covid Brain
“But this week 2 new publications have substantially added to our understanding of the extent that Covid can impair cognitive function across the full gamut— from young, healthy individuals with mild infections to older, hospitalized patients with severe Covid.”
·erictopol.substack.com·
Covid Brain
Research Shows Severe COVID-19 Contributes to Long-Lasting Cognitive Impairment - InventUM
Research Shows Severe COVID-19 Contributes to Long-Lasting Cognitive Impairment - InventUM

“We found persistent subjective and objective cognitive issues even two years after infection, including brain fog, word-finding problems, working memory deficits and reduced processing speed.” “Most Patients Have Never Fully Recovered”

“We found persistent subjective and objective cognitive issues even two years after infection, including brain fog, word-finding problems, working memory deficits and reduced processing speed.” “Most Patients Have Never Fully Recovered”
·news.med.miami.edu·
Research Shows Severe COVID-19 Contributes to Long-Lasting Cognitive Impairment - InventUM
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Non paywall version of catalogued Bloomberg article
Scientists are worried that persisting cognitive issues may signal a coming surge of dementia and other mental conditions
·archive.is·
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2
·pubmed.ncbi.nlm.nih.gov·
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
Low Cortisol Levels May Be Key to Long COVID Symptoms
Low Cortisol Levels May Be Key to Long COVID Symptoms

Yet another stretch for one size fits all explanation of a multifaceted condition. Still, important finding:

“A groundbreaking study from the University of Colorado Boulder has uncovered a potential mechanism behind the persistent neurological symptoms experienced by many Long COVID sufferers. The research, published in Brain, Behavior, and Immunity, points to a significant drop in cortisol levels in the brain as a possible culprit, offering new insights into this complex and widespread condition.”

·scienceblog.com·
Low Cortisol Levels May Be Key to Long COVID Symptoms
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota

EXTREME and incomplete oversimplification of the many complex neurological issues caused by SarsCov2, but important facet of the vaguely defined “brain fog” of Long Covid and post-acute Covid lingering symptoms.

“Neurological symptoms have been widely observed in COVID-19 patients, with many survivors exhibiting persistent neurological and cognitive impairment. New research from the University of Minnesota found that COVID-19 triggers inflammation in the brain, which is linked to many COVID-related symptoms such as fatigue and ‘brain fog.’”

·twin-cities.umn.edu·
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota