Alzheimer’s disease-like changes in COVID-19
Plasma proteomic evidence for increased β-amyloid pathology after SARS-CoV-2 infection
UK study of 1,252 people finds SARS-CoV-2 may accelerate Alzheimer’s-related brain changes.
Infected individuals showed shifts in key biomarkers, with greater effects in hospitalized patients and those with hypertension.
The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline
“The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline”
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc
“The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc
An unparalleled horror show & crime.”
Are some cases of Alzheimer's disease caused by infection? - Harvard Health
“The virus that causes COVID-19, known as SARS-CoV-2, may also make the brain vulnerable to Alzheimer's”
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
SARS-CoV-2 and HSV-1 induce amyloid aggregation, depleting soluble proteins.
Suggests a link between viral infections and neurodegenerative diseases via protein loss.
Frontiers | Frequency of Neurological Diseases After COVID-19, Influenza A/B and Bacterial Pneumonia
A study of electronic medical records of 35,362 COVID-19 outpatients in Denmark showed an increased relative risk (RR) of 3.5 for Alzheimer's disease and 2.6 for Parkinson's disease compared to outpatients who did not have COVID-19.
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
“We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease”
We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease
Emerging signs of Alzheimer‐like tau hyperphosphorylation and neuroinflammation in the brain post recovery from COVID‐19
Emerging signs of Alzheimer’s-like pathology in brains if people recovered from COVID-19, even though no direct SARS-CoV-2 invasion was detected
Frontiers | Unravelling the connection between COVID-19 and Alzheimer’s disease: a comprehensive review
“Unravelling the connection between COVID-19 and Alzheimer’s disease: a comprehensive review”
Association of COVID-19 with New-Onset Alzheimer’s Disease - IOS Press
COVID infection increases the risk of Alzheimer's by about 70% in older people.
Long COVID patients have similar brain activity to those with dementia, UK researchers find
“Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.”
Kentucky research links long COVID brain fog to Alzheimer’s | Lexingt…
“Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.”
Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Non paywall version of catalogued Bloomberg article
Scientists are worried that persisting cognitive issues may signal a coming surge of dementia and other mental conditions
What We Know About Covid’s Impact on Your Brain
“Scientists are worried that persisting cognitive issues may signal a coming surge of dementia and other mental conditions”
Alzheimer's-like brain changes found in long COVID patients
“New research from the University of Kentucky's Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen in Alzheimer's disease and related dementias.”
UK researchers find Alzheimer’s-like brain changes in long COVID patients
“New research from the University of Kentucky’s Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen in Alzheimer’s disease and related dementias.”
Does Long COVID Lead to Alzheimer's? A New Study Took an Unexpected Turn
“More than one in ten people who catch COVID don’t fully recover — developing a chronic condition called Long COVID which causes a variety of debilitating symptoms, including brain fog. Since some studies have found that COVID infections are associated with overall brain shrinkage, altered brain structure, and an increased risk of developing Alzheimer’s, researchers have been investigating the links between COVID and Alzheimer’s.”
More than one in ten people who catch COVID don’t fully recover — developing a chronic condition called Long COVID which causes a variety of debilitating symptoms, including brain fog. Since some studies have found that COVID infections are associated with overall brain shrinkage, altered brain structure, and an increased risk of developing Alzheimer’s, researchers have been investigating the links between COVID and Alzheimer’s.
Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons
“It is now evident that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection results in a wide range of long-term neurological symptoms and is worryingly associated with the aggravation of Alzheimer’s disease. Little is known about the molecular basis of these manifestations.”
Nate Bear on Twitter
Thread on Twitter: New study documents the case of two previously healthy sisters - 11 and 13-years-old - with new-onset cognitive decline after mild covid. The ability of their brains to consume glucose had been impaired - an initiating factor for dementia, Parkinson's and Alzheimer's disease 🧵
COVID-19 could put us at a greater risk of neurodegenerative diseases and stroke
"Analysis of nearly one million Danish health records has found patients who tested positive for COVID-19 were subsequently more likely to be diagnosed with Alzheimer’s disease, Parkinson’s disease and stroke."
One-two punch from pair of common viruses may trigger Alzheimer’s disease
Related: "potential future Alzheimer’s problems may arise from the COVID-19 pandemic as SARS-CoV-2 infections have been known to reactivate dormant VSV and HSV-1 infections...the pandemic could increase future rates of neurodegenerative disease"
New study shows SARS-CoV-2 infection accelerates the progression of dementia
"All subtypes of dementia, irrespective of patients’ previous dementia types, behaved like rapidly progressive dementia following COVID-19, according to the Journal of Alzheimer’s Disease Reports"
Could viruses cause Alzheimer's? COVID-19 brain studies offer new clues.
Could viruses cause Alzheimer's? COVID-19 brain studies offer new clues.
COVID-19 May Cause Higher Alzheimer's Risk
"Researchers say people over 65 who’ve had COVID-19 have as much as an 80% higher risk of developing Alzheimer’s disease within a year."
COVID-19 amplifies damage to the central nervous system in Alzheimer's disease
"COVID-19 amplifies damage to the central nervous system in Alzheimer's disease"
Like a "fire in the brain": COVID can cause brain inflammation
"A new study in the journal Molecular Psychiatry shows for the first time that SARS-2 can trigger the same inflammatory processes seen in patients with Alzheimer's or Parkinson's."
'A silent killer': COVID-19 shown to trigger inflammation in the brain
Another study showing that metabolic pathways activated in brain by covid are similar to the ones that happen in Alzheimer & Parkinson diseases. While the drugs to stop this inflammation are being tested, the inflammation is affecting millions of ppl.
COVID increases risk of 44 different neuro disorders, including Alzheimer's, 1 year post-infection
"COVID increases risk of 44 different neuro disorders, including Alzheimer's, 1 year post-infection"
Risk for Developing Alzheimer’s Disease Increases by 50-80% In Older Adults Who Caught COVID-19 - Neuroscience News
"Older people who were infected with COVID-19 show a substantially higher risk—as much as 50% to 80% higher than a control group—of developing Alzheimer’s disease within a year, according to a study of more than 6 million patients 65 and older."