Covid and Brain Damage

Covid and Brain Damage

#Brain
A groundbreaking study aims to determine if long COVID-19 could lead to another type of dementia
A groundbreaking study aims to determine if long COVID-19 could lead to another type of dementia

“‘…there is evidence of fragments or an inflammatory kind of a massive inflammatory response that occurs triggered by COVID. And those inflammatory markers we tend to notice in the brain.’

And that could cause something called COVID-19 Cognitive Impairment.

‘And we are going to compare people with COVID cognitive impairment. To be clear on this, I think that COVID can cause cognitive impairment and maybe even dementia…’”

·kjzz.org·
A groundbreaking study aims to determine if long COVID-19 could lead to another type of dementia
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2
·pubmed.ncbi.nlm.nih.gov·
Prevalence and co-occurrence of cognitive impairment in children and young people up to 12-months post infection with SARS-CoV-2 (Omicron variant) - PubMed
COVID-related loss of smell tied to changes in the brain | CIDRAP
COVID-related loss of smell tied to changes in the brain | CIDRAP
“On MRI conducted during the game, loss of smell was associated with decreased functional activity during decision-making, loss of white-matter integrity, and thinning of the outer layer of the cerebrum in the parietal regions (responsible for processing sensory input, understanding spatial relationships, and how to navigate).”
·cidrap.umn.edu·
COVID-related loss of smell tied to changes in the brain | CIDRAP
Low Cortisol Levels May Be Key to Long COVID Symptoms
Low Cortisol Levels May Be Key to Long COVID Symptoms

Yet another stretch for one size fits all explanation of a multifaceted condition. Still, important finding:

“A groundbreaking study from the University of Colorado Boulder has uncovered a potential mechanism behind the persistent neurological symptoms experienced by many Long COVID sufferers. The research, published in Brain, Behavior, and Immunity, points to a significant drop in cortisol levels in the brain as a possible culprit, offering new insights into this complex and widespread condition.”

·scienceblog.com·
Low Cortisol Levels May Be Key to Long COVID Symptoms
Brain effects of mild COVID-19 in healthy young adults: A pilot study
Brain effects of mild COVID-19 in healthy young adults: A pilot study
“Our pilot data suggests that mild COVID-19 may result in brain pathology and impact neurocognitive function in younger adults in a manner parallel to prior findings in older individuals. Though findings may not generalize to other SARS-CoV-2 variants, larger longitudinal studies of mild COVID-19 should be undertaken to understand the potential clinical implications of these findings over the longer term.”
Our pilot data suggests that mild COVID-19 may result in brain pathology and impact neurocognitive function in younger adults in a manner parallel to prior findings in older individuals. Though findings may not generalize to other SARS-CoV-2 variants, larger longitudinal studies of mild COVID-19 should be undertaken to understand the potential clinical implications of these findings over the longer term.
·cell.com·
Brain effects of mild COVID-19 in healthy young adults: A pilot study
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota

EXTREME and incomplete oversimplification of the many complex neurological issues caused by SarsCov2, but important facet of the vaguely defined “brain fog” of Long Covid and post-acute Covid lingering symptoms.

“Neurological symptoms have been widely observed in COVID-19 patients, with many survivors exhibiting persistent neurological and cognitive impairment. New research from the University of Minnesota found that COVID-19 triggers inflammation in the brain, which is linked to many COVID-related symptoms such as fatigue and ‘brain fog.’”

·twin-cities.umn.edu·
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations
Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations
: “Patients who presented with anosmia exhibited more IMPULSIVE alternative changes…Anosmia correlated with brain measures, including decreased functional activity during the decision-making task, thinning of cortical thickness in parietal regions, and loss of white matter integrity.”
·nature.com·
Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations
Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations
Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations
“Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations”
·x.com·
Patients recovering from COVID-19 who presented with anosmia during their acute episode have behavioral, functional, and structural brain alterations
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
“This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, all the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...”
·x.com·
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
Want to see what a “COVID Brain” can look like?
Want to see what a “COVID Brain” can look like?

“Want to see what a “COVID Brain” can look like?

Here’s mine. The white spots are not supposed to be there. You can’t see the microhemorrhages or swelling.

Infected early March ‘20- pre-vaccine.But the threat is still here for everyone-vax or not, young or old.

Please mask up.”

·x.com·
Want to see what a “COVID Brain” can look like?
Mounting research shows that COVID-19 leaves its mark on the brain, including significant drops in IQ scores
Mounting research shows that COVID-19 leaves its mark on the brain, including significant drops in IQ scores

In addition to brain fog, COVID-19 can lead to an array of problems, including headaches, seizure disorders, strokes, sleep problems, and tingling and paralysis of the nerves, as well as several mental health disorders. A large and growing body of evidence amassed throughout the pandemic details the many ways that COVID-19 leaves an indelible mark on the brain. But the specific pathways by which the virus does so are still being elucidated, and curative treatments are nonexistent.

·timesunion.com·
Mounting research shows that COVID-19 leaves its mark on the brain, including significant drops in IQ scores
Three years after your initial covid infection, there were still *new* symptoms starting, mostly neurological or GI related. 'That mini stroke that you are having now could be related to that covid infection you had three years ago.' TY
Three years after your initial covid infection, there were still *new* symptoms starting, mostly neurological or GI related. 'That mini stroke that you are having now could be related to that covid infection you had three years ago.' TY
Three years after your initial covid infection, there were still new symptoms starting, mostly neurological or GI related. 'That mini stroke that you are having now could be related to that covid infection you had three years ago.'
·x.com·
Three years after your initial covid infection, there were still *new* symptoms starting, mostly neurological or GI related. 'That mini stroke that you are having now could be related to that covid infection you had three years ago.' TY
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
University of Colorado study in rats demonstrates that SARS-CoV-2 protein activity drives longer-term vulnerability to another infection, augmenting physiological problems such as neuroinflammation, autonomic dysregulation, and hormonal imbalances
University of Colorado study in rats demonstrates that SARS-CoV-2 protein activity drives longer-term vulnerability to another infection, augmenting physiological problems such as neuroinflammation, autonomic dysregulation, and hormonal imbalances
·polybio.org·
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure | PLOS Pathogens
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure | PLOS Pathogens
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure
·journals.plos.org·
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure | PLOS Pathogens
SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19
SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19
“Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of coronavirus disease 2019 (COVID-19), can induce a plethora of neurological complications in some patients. However, it is still under debate whether SARS-CoV-2 directly infects the brain or whether CNS sequelae result from systemic inflammatory responses triggered in the periphery. By using high-resolution microscopy, we investigated whether SARS-CoV-2 reaches the brain and how viral neurotropism can be modulated by aging in a non-human primate model of COVID-19.”
·cell.com·
SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19
Dumb and Dumber?
Dumb and Dumber?

Dumb and Dumber? IQ loss on every COVID-19 infection?

⁃Your doctor & surgeon ⁃Your pilot ⁃Your heads of state ⁃Driver in the car next to you ⁃Your brain 🧠?

Studies have provided substantial evidence that COVID-19 damages the brain, revealing a range of cognitive and neurological damage:

·x.com·
Dumb and Dumber?
2023
2023

SARS-CoV-2 Spike Protein Accumulation in the Skull-Meninges- Brain Axis: Potential Implications for Long-Term Neurological Complications in post-COVID-19 Zhouyi Rong1,2,15†, Hongcheng Mai1,2,15†, Saketh Kapoor1†, Victor G. Puelles3,4,13,14,

·biorxiv.org·
2023