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Thread by @JamesThrot on Thread Reader App
Thread by @JamesThrot on Thread Reader App

“Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵”

Let’s talk about COVID, brain damage & society. Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences? This thread is for the skeptics. I’m a neurologist, stay with me 🧵
#Brain#Covid Isn't Over#Post-Acute Conditions#consequences#frontal lobe#brain dysfunction#cognition#cognitive decline#Long Covid#neurological#Post-Acute Sequelae of COVID-19#Cognitive Impairment#white matter#grey matter shrinkage#olfactory damage#working memory#Discussion#analysis#James Throt
·threadreaderapp.com·
Thread by @JamesThrot on Thread Reader App
Human challenge study reveals lasting cognitive decline after mild COVID-19
Human challenge study reveals lasting cognitive decline after mild COVID-19

“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
#cognitive decline#memory#long covid#cognition#Cognitive Impairment#Brain Fog#Long Covid#Post-Acute Conditions#Brain#neurological
·news-medical.net·
Human challenge study reveals lasting cognitive decline after mild COVID-19
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
“Dysregulation of autoimmune responses and the presence of autoantibodies (AA), particularly those related to the renin-angiotensin system (RAS), have been implicated in the acute phase of COVID-19, and persistent dysregulation of brain RAS by RAS-related autoantibodies may also contribute to neurological symptoms of post-COVID.”
Dysregulation of autoimmune responses and the presence of autoantibodies (AA), particularly those related to the renin-angiotensin system (RAS), have been implicated in the acute phase of COVID-19, and persistent dysregulation of brain RAS by RAS-related autoantibodies may also contribute to neurological symptoms of post-COVID.
#autoimmunity#neurological#Post-Acute Conditions#Long Covid#Immune system#brain#Neuroaxonal damage
·frontiersin.org·
Frontiers | Serum angiotensin type-1 receptor autoantibodies and neurofilament light chain as markers of neuroaxonal damage in post-COVID patients
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
“A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.”
A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.
#Neuroinflammation#brain inflammation#brain fog#cognition#Brain#Cognition#Cognitive Impairment#Long Covid
·medicalxpress.com·
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
How COVID Impacts the Brain: Danielle Beckman and David Joffe
How COVID Impacts the Brain: Danielle Beckman and David Joffe
“How does COVID-19 impact the brain? Neuroscientist Danielle Beckman and expert David Joffe discuss direct neuronal effects and sleep disorders in Long COVID patients, and the importance of thorough evaluations for accurate diagnoses.”
#Brain#Cognitive decline#Long Covid#Memory#neurodegeneration#brain#neuronal effects#sleep#sleep disturbances#David Joffe#video#Danielle Beckman#podcast
·youtube.com·
How COVID Impacts the Brain: Danielle Beckman and David Joffe
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
“Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.”
Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.
#Long Covid#Post-Acute Conditions#brain#neuroimaging#hypometabolism#Cognitive Impairment#neurological
·link.springer.com·
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
#Ears#Post-Acute Conditions#Auditory System#Long Covid#Brain#PASC#neurological#long covid#hearing loss#tinnitus#Fatigue#ANA test#Depression#cognitive decline
·nature.com·
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

Exploring the Persistence of the Spike Protein along the Skull-Meninges-Brain Axis and the Neurological Effects of COVID-19

This analysis is supported by numerous videos and illustrations.

#Brain#Long Covid#Neuroinflammation#Post-Acute Conditions#brain injury#meninges#neurologic changes#neurological#spike protein#skull
·cell.com·
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
#Brain#Brain shrinkage#brain atrophy#Long Covid#Post-Acute Conditions#cognitive decline#cognition#organ damage
·academic.oup.com·
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
#Brain#Cognition#cognitive decline#Cognitive decline#Brain fog#Neuroinflammation#Post-Acute Conditions#Long Covid#organ damage
·x.com·
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
“197 patients were included, presenting with vascular syndromes (81), encephalopathy (68), encephalitis (19), Guillain-Barré syndrome (13), other neuropathies (12), and myelitis (4). The incidence curve of neurocovid mirrored that of COVID-19. Neurological syndromes were present regardless of COVID-19 severity. The median time from COVID-19 to onset of neurological symptoms was 14 days, suggesting a post-infectious immune-mediated mechanism.”
#Brain#Long Covid#neurological#neurologic changes#Neurovascular#vascular#Guillain-Barre#encephalopathy#brain injury
·flip.it·
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
Long Covid ‘changes brains of people differently to those who recover from virus’
Long Covid ‘changes brains of people differently to those who recover from virus’

“Long Covid ‘changes brains of people differently to those who recover from virus’

More than two million people in the UK are thought to be suffering from long Covid”

As many as 10-25% of people who get Covid will get Long Covid.

Long Covid ‘changes brains of people differently to those who recover from virus’More than two million people in the UK are thought to be suffering from long Covid
#Brain#brain changes#long covid#Covid Statistics
·independent.co.uk·
Long Covid ‘changes brains of people differently to those who recover from virus’
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
“A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein.”
A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein.
#Brain#Viral Persistence#spike protein#Long Covid#neurologic changes#Neurological Complications#neurological#brain aging
·scitechdaily.com·
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students

“COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students”

“37 % of the undergraduates exhibited impaired cognition up to 17 months post-infection.”

#Brain#cognition#brain injury#Long Covid#Memory#cognitive decline#Cognitive Impairment#brain haemodynamics#young people#undergraduate students
·sciencedirect.com·
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students