Harry Spoelstra (@HarrySpoelstra) on X
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.
Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms: A pilot study | PLOS One
A Case Report of Normal Pressure Hydrocephalus Developing After COVID-19 Infection
A Case Report of Normal Pressure Hydrocephalus Developing After COVID-19 Infection
A Case Report of Normal Pressure Hydrocephalus Developing After COVID-19 Infection
Unusual Post–COVID-19 Presentation With Tetraventricular Hydrocephalus | Neurology Clinical Practice
“COVID-19 infection is suggested as one of the causes for hydrocephalus (HCP) of unknown etiology. “
COVID-19 infection is suggested as one of the causes for hydrocephalus (HCP) of unknown etiology.
Normal pressure hydrocephalus associated with COVID-19 infection: a case report - BMC Infectious Diseases
Hydrocephalus secondary to COVID-19 infection | QJM: An International Journal of Medicine | Oxford Academic
Normal pressure hydrocephalus associated with COVID-19 infection: a case report
“Other infections such as syphilis, cryptococcosis and Lyme disease have been associated with NPH. Possible mechanisms for NPH after COVID include disruption of choroid plexus cells by direct viral invasion or as a result of neuroinflammation and cytokine release and hypercoagulability leading to venous congestion and abnormalities of CSF flow.”
Other infections such as syphilis, cryptococcosis and Lyme disease have been associated with NPH. Possible mechanisms for NPH after COVID include disruption of choroid plexus cells by direct viral invasion or as a result of neuroinflammation and cytokine release and hypercoagulability leading to venous congestion and abnormalities of CSF flow.
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Jess 🇨🇦 (@MeetJess) on X
Repeat COVID Infections & Dementia
A time bomb no one wants to talk about 🧵
Altered brain glucose metabolism in COVID-19 disease: an activation likelihood estimation meta-analysis of PET studies - PubMed
Radical Centrist,wrathful tantric deity🇺🇦🇹🇼🎗️ (@RadCentrism) on X
“Weird. If only some people discussed this 4-5 years ago…”
Kathryn (@kadamssl) on X
“That feeling when you know COVID can cause damage to the orbitofrontal cortex and you also know that this is almost certainly contributing to loss of empathy, increased impulsivity, and a prevalent inability to learn that changed circumstances warrant changed behaviour. 👇”
Expert warns common virus dramatically raises risk of early dementia
“Top scientists have warned that those who've had Covid may be at greater risk of developing dementia before they reach 70.”
Top scientists have warned that those who've had Covid may be at greater risk of developing dementia before they reach 70.
newsGP - How COVID-19 leaves its mark on the brain
“Mounting research shows the disease can lead to an array of problems, including significant drops in IQ scores, writes Dr Ziyad Al-Aly.”
Mounting research shows the disease can lead to an array of problems, including significant drops in IQ scores, writes Dr Ziyad Al-Aly.
Why Does My Perfume Smell Weird So Weird On Me Now? Is It Perimenopause?
Or you have Covid induced olfactory disorder.
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
“Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.”
Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
Thread by @JamesThrot on Thread Reader App
“In neurology/psychiatry, we would call this Apathy.
Brain damage to the frontal lobe (dorsal anterior cingulate cortex) causes apathy & reduces empathy.
SARS-CoV-2 damages this region of the brain. Every. Single. Time.
More infections = more damage = more apathy.”
In neurology/psychiatry, we would call this Apathy.
Brain damage to the frontal lobe (dorsal anterior cingulate cortex) causes apathy & reduces empathy.
SARS-CoV-2 damages this region of the brain. Every. Single. Time.
More infections = more damage = more apathy.
Investigating the Neuroimmune, Cerebrovascular, and Cognitive Disturbances Associated with SARS‑CoV‑2 Infection: A Systematic Review of Post‑Acute Outcomes | Research Square
“A systematic review of 73,435 COVID-19 survivors found that 42% had persistent neuroinflammation, 22% had cerebrovascular injury, and 58% had cognitive impairment.”
SARS-CoV-2 affects Alzheimer’s disease
"Patients suffering from COVID-19 have been found to exhibit dementia-related biomarkers.. The findings of this study suggest a potential link between mild-to-moderate SARS-CoV-2 infection and the initiation or acceleration of brain β-amyloid pathology, and hint at the possibility of an increased future incidence of Alzheimer’s disease subsequent to the COVID-19 pandemic."
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Exploring the Persistence of the Spike Protein along the Skull-Meninges-Brain Axis and the Neurological Effects of COVID-19
This analysis is supported by numerous videos and illustrations.
Cerebrospinal Fluid Offers Clues to Post-COVID ‘Brain Fog’ | UC San Francisco
“Over-Stimulated Immune System May Be Impetus to Cognitive Symptoms, UCSF-Led Study Shows”
What We Know About Covid’s Impact on Your Brain
“Scientists worry that persistent cognitive issues caused by Covid signal that a surge in dementia cases and other mental conditions is on the horizon’
Have you developed symptoms of ADHD since 2020? Or has your ADHD deteriorated since 2020? The frontal lobe is the largest part of the brain affected by ADHD, often maturing at a slower pace with disrupted activity & connectivity. Covid damages the frontal & temporal lobes. 🧵 https://t.co/Jhu5XWJjfE— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) March 3, 2025
“Have you developed symptoms of ADHD since 2020?
Or has your ADHD deteriorated since 2020?
The frontal lobe is the largest part of the brain affected by ADHD, often maturing at a slower pace with disrupted activity & connectivity.
Covid damages the frontal & temporal lobes.
🧵”
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025
“Covid 19 is causing widespread brain damage on a global scale.
SARS-CoV-2 damages the brain. FACT.
Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation.
The signs are clear.
Signed, a neurologist
🧵”
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
“Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review”
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
New neuroscience research shows COVID-19 leaves mark on young adult brains
“A new study published in Brain, Behavior, and Immunity has found that young adults who have recovered from COVID-19 show distinct patterns of brain activity during cognitive tasks, even if they perform normally on those tasks. These brain activity changes are similar to those seen in much older adults and are particularly pronounced in individuals reporting ‘brain fog.’”
A new study published in Brain, Behavior, and Immunity has found that young adults who have recovered from COVID-19 show distinct patterns of brain activity during cognitive tasks, even if they perform normally on those tasks. These brain activity changes are similar to those seen in much older adults and are particularly pronounced in individuals reporting “brain fog.”