SARS-CoV-2 and HSV-1 induce amyloid aggregation, depleting soluble proteins.

Suggests a link between viral infections and neurodegenerative diseases via protein loss.

Evidence that a COVID-19 infection can induce neurological sequelae.

The SARSCoV2 spike protein can persist in the brain—skull bone marrow and meninges—to induce neurologic damage

SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it.

In mice, it caused inflammation, anxiety, and worsened brain injuries. Vaccines reduced but did not fully eliminate it.

“The Omicron variant of SARS-CoV-2 presents a wide spectrum of neurological manifestations."

"Although there is an improvement in the survival rate of patients with COVID-19, the frequency of neurological manifestations increases."

"The occurrence of delirium, cerebrovascular diseases, and ischemic stroke results in higher mortality."

“If you’re not noticing the (obvious) cognitive impairment in practically everyone around you, it may be due to your own cognitive decline.

Or denial is rearing its ugly head once again.

Perhaps it’s easier for me considering my background, but honestly, it’s so bloody palpable.”

Nearly half of those infected with SARS-CoV-2 experience long-term neurological problems, including brain fog and memory issues.

An infection may accelerate or exacerbate prion diseases like Creutzfeldt–Jakob disease, leading to rapid neurodegeneration.

Covid itself causes cognitive impairment. From 2020, prior to Covid vaccination of any kind:

“In our cohort of COVID-19 patients neurologic manifestations were frequent, including cognitive impairment.”

A new paper in Cell, “Pioneering discovery and therapeutics at the brain-vascular-immune interface,” describes COVID-19 as a neurological disease alongside multiple sclerosis, Alzheimer’s, stroke and traumatic brain injury.

“COVID-19 can accelerate progression of dementia and induce BBB disruption and inflammatory blood clots causally linked with neuroinflammation and neuronal loss.8 In neurodevelopmental disorders, prematurity and perinatal hypoxia that trigger brain hemorrhage and BBB disruption are risk factors for cerebral palsy, intellectual disability, and autism. Collectively, these risk factors highlight the interconnected vascular and immune triggers of neurological diseases.”

Very comprehensive evaluation of known neurological damage from SarsCov2:

“The pathogenesis of neurological disorders caused by SARS-CoV-2 involves several mechanisms. First, SARS-CoV-2 could enter the brain through retrograde transmission & hematogenous routes & disrupt brain function & structure, thus causing or exacerbating neurological disorders…”

SARS2 can invade your brain.

All variants are neuroinvasive.

Neuroinvasion and anosmia are independent phenomena upon infection.

SARS2 can travel retrogradely and anterogradely along axons in neuron-epithelial networks.

Forbes: 'InnovationRx: COVID May Be Causing Mental Illness—And Rewiring Our Brains'

New findings in JAMA Psychiatry find that levels of mental illness such as depression, anxiety and self-harm are elevated after a COVID-19 diagnosis

“‘…there is evidence of fragments or an inflammatory kind of a massive inflammatory response that occurs triggered by COVID. And those inflammatory markers we tend to notice in the brain.’

And that could cause something called COVID-19 Cognitive Impairment.

‘And we are going to compare people with COVID cognitive impairment. To be clear on this, I think that COVID can cause cognitive impairment and maybe even dementia…’”

Yet another stretch for one size fits all explanation of a multifaceted condition. Still, important finding:

“A groundbreaking study from the University of Colorado Boulder has uncovered a potential mechanism behind the persistent neurological symptoms experienced by many Long COVID sufferers. The research, published in Brain, Behavior, and Immunity, points to a significant drop in cortisol levels in the brain as a possible culprit, offering new insights into this complex and widespread condition.”