The biologic underpinnings of #LongCovid neurologic sequelae https://cell.com/neuron/fulltext/S0896-6273(22)00910-2 @NeuroCellPress by @michelle_monje and @VirusesImmunity
Comprehensive thread on Twitter> Glad to share this Perspective written with @VirusesImmunity , where we review what is understood about how COVID can affect the brain, discuss the possible neurobiological underpinnings & propose the main mechanisms that may contribute to COVID brain fog🧵
"scientists found evidence that antibodies—proteins produced by the immune system in response to viruses and other invaders--are involved in an attack on the cells lining the brain’s blood vessels..." Cross-referenced in thread on Covid & immune system
Comprehensive explanation thread: 1/🧵 The Haunting Brain Science of Long COVID 🧠
@washingtonpost Aug 25
📍Brain shrinking 📍Corona ghosts 📍Autoimmunity 📍Clinical clusters
“The good news is that in some pts #LongCovid #BrainFog may not be permanent.”
Link👇 but paywall so see 🧵
"Covid-19 can severely damage your child's brain.
The research identifies a wide spectrum of neurological complications in children and suggests they may be more common than in adults admitted with Covid-19."
"How COVID-19 Can Affect Your Child's Brain
Some children develop neurological symptoms from COVID-19, including brain fog, memory issues, headaches, and trouble concentrating. We spoke with pediatric neurologists to learn more..."
COVID-19: Long COVID Neuroinflammation shown in PET scan
A study shows positron emission tomography (PET) scan imaging of two Long COVID patients compared with controls (
Thread on Twitter: 1/🧵Brain Dz in Long COVID 🧠
📌 This remarkable study of >1M COVID pts found mood & anxiety disorders improved 📌 BUT Acquired #BrainFog (dementia), psychosis & seizures persist at 2 YEARS. 📌 Omicron as bad as Delta
Devastating.
#vaxx & #mask indoors
%3Amax_bytes(150000)%3Astrip_icc()%2FGettyImages-1286540630-18796ea07ba4466f895d92e9cbc2b682.jpg?width=350&height=&ar=16:9&mode=crop&format=avif&dpr=2)
%3Amax_bytes(150000)%3Astrip_icc()%2FGettyImages-1316763026-2000-c56de8cd4ff1416799e9b726fd7bbc36.jpg?width=350&height=&ar=16:9&mode=crop&format=avif&dpr=2)
![Long COVID is associated with extensive in-vivo neuroinflammation on [18F]DPA-714 PET](https://rdl.ink/render/https%3A%2F%2Fwww.medrxiv.org%2Fsites%2Fdefault%2Ffiles%2Fimages%2Fmedrxiv_logo_homepage7-5-small-test-up.png?width=350&height=&ar=16:9&mode=crop&format=avif&dpr=2){kind=logo}
