UK researchers scanned the brains of 400 people before and after mild covid, compared them with controls and found:
- greater reduction in grey matter thickness
- greater reduction in global brain size
- greater cognitive decline
- greater change to primary olfactory cortex
Covid linked to significant brain shrinkage: "Even a mild COVID-19 infection can change the brain. People infected had a greater reduction in brain volume and performed worse on cognitive tests than those who did not contract COVID-19."
According to a systematic review on the COVID-19 survivors, "Seventy-nine percent of COVID-19 survivors at 1 months and 75% at 3- and 6-month follow-up showed cognitive impairment.."
3 in 4 is a quite high ratio.
COVID cognitive decline more widespread than thought say researchers at Australia's first long-COVID clinic Some sort of cognitive decline was recorded in almost all of the participants, regardless of the severity of the initial infection.
Comprehensive thread on Twitter 1/36 Update of the covid and the brain talk I recently gave to Drs at Select Medical Better quality figures More on references to look up: Lancet, NEJM, Nature, Neurology, etc Some new material dispersed and at end Some thoughts on possible treatments (not my expertise)
Excellent study from Oxford💥💥 This is the first report describing deficits in sustained attention & episodic memory amongst mildly-affected #COVID19 survivors long after the acute illness, in people who were not complaining of long-COVID symptoms
Covid-19 And Parkinson’s Disease Can Be A Dangerous Combination:
The viral disease has affected the brain to quite an extent. The immune response in the brain is what gets affected first and then there is the direct invasion of the coronavirus.
Severe cases of COVID causing cognitive impairment equivalent to ageing 20 years, new study finds
"It is very possible that some of these individuals will never fully recover,"
Comprehensive thread on Twitter: sleepiness, ophthalmoplegia, Parkinsonism, spontaneous movements, dysuria & constipation which we consider characteristic of lethargic encephalitis, due to the position of the lesions in the brainstem THE OCULAR COMPLICATIONS OF ENCEPHALITIS LETHARGICA
Comprehensive thread on Twitter: 1/ Covid New Study Shows bleeding on the brain, neuron death & damage, severe inflammation including the 'mild': cases virus found in cells that line the Brain and brainstem—new insight into Long Covid, strokes and other brain disease
"Bluntly and rather disconcertingly, Pirzada says if someone is dealing with significant brain fog, there isn’t much that can be done...
'We can refer you to a specialist that will see you in the long term, but they won’t know what to do either,'"