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Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

Exploring the Persistence of the Spike Protein along the Skull-Meninges-Brain Axis and the Neurological Effects of COVID-19

This analysis is supported by numerous videos and illustrations.

·cell.com·
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
·academic.oup.com·
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
“Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review”
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
·mdpi.com·
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
·x.com·
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
“197 patients were included, presenting with vascular syndromes (81), encephalopathy (68), encephalitis (19), Guillain-Barré syndrome (13), other neuropathies (12), and myelitis (4). The incidence curve of neurocovid mirrored that of COVID-19. Neurological syndromes were present regardless of COVID-19 severity. The median time from COVID-19 to onset of neurological symptoms was 14 days, suggesting a post-infectious immune-mediated mechanism.”
·flip.it·
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
Long Covid ‘changes brains of people differently to those who recover from virus’
Long Covid ‘changes brains of people differently to those who recover from virus’

“Long Covid ‘changes brains of people differently to those who recover from virus’

More than two million people in the UK are thought to be suffering from long Covid”

As many as 10-25% of people who get Covid will get Long Covid.

Long Covid ‘changes brains of people differently to those who recover from virus’More than two million people in the UK are thought to be suffering from long Covid
·independent.co.uk·
Long Covid ‘changes brains of people differently to those who recover from virus’
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
“A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein.”
A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein.
·scitechdaily.com·
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests

“Post-Covid cognitive impairment affects daily function and quality of life. • ACE-III fails to detect cognitive impairment in most post-Covid patients. • 89% of patients have impaired attention, executive function, processing speed on novel tests. • New tests are needed for post-Covid cognitive assessment in clinical practice.”

Post-Covid cognitive impairment affects daily function and quality of life.•ACE-III fails to detect cognitive impairment in most post-Covid patients.•89% of patients have impaired attention, executive function, processing speed on novel tests.•New tests are needed for post-Covid cognitive assessment in clinical practice.
·sciencedirect.com·
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students

“COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students”

“37 % of the undergraduates exhibited impaired cognition up to 17 months post-infection.”

·sciencedirect.com·
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
“Using the golden hamster as a model, we provide further evidence that SARS-CoV-2 is neuroinvasive and can persist in the central nervous system, as we found viral RNA and replicative virus in the brainstem after 80 days of infection.”
·biorxiv.org·
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics

Older adults recovering from COVID-19 face a 58% higher risk of developing dementia compared to those uninfected, with rates peaking 12 months post-infection.

Study reviewed 11 studies, 940k cases, 6.8M controls.

·bmcgeriatr.biomedcentral.com·
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
“The study shows that the SARS-CoV-2 spike protein remains in the brain's protective layers, the meninges, and the skull's bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases.”
The study shows that the SARS-CoV-2 spike protein remains in the brain's protective layers, the meninges, and the skull's bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases.
·medicalxpress.com·
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19

Evidence that a COVID-19 infection can induce neurological sequelae.

The SARSCoV2 spike protein can persist in the brain—skull bone marrow and meninges—to induce neurologic damage

SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it.

In mice, it caused inflammation, anxiety, and worsened brain injuries. Vaccines reduced but did not fully eliminate it.

·cell.com·
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Honestly it kinda pisses me off how some people act like we can't talk about the brain damage from Covid, especially on the population level.
Honestly it kinda pisses me off how some people act like we can't talk about the brain damage from Covid, especially on the population level.

“Honestly it kinda pisses me off how some people act like we can't talk about the brain damage from Covid, especially on the population level. Yes, it's important to consider the ableism. But I have brain damage from Covid, including to my emotions, and we need to talk about it...”

·x.com·
Honestly it kinda pisses me off how some people act like we can't talk about the brain damage from Covid, especially on the population level.
Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron Subvariants—Single-Center Study
Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron Subvariants—Single-Center Study

“The Omicron variant of SARS-CoV-2 presents a wide spectrum of neurological manifestations."

"Although there is an improvement in the survival rate of patients with COVID-19, the frequency of neurological manifestations increases."

"The occurrence of delirium, cerebrovascular diseases, and ischemic stroke results in higher mortality."

·mdpi.com·
Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron Subvariants—Single-Center Study
We Just Got More Evidence That Long COVID Is a Brain Injury
We Just Got More Evidence That Long COVID Is a Brain Injury

“Signs of brain inflammation were present up to 18 months after first contracting the SARS-CoV-2 virus.

‘We show that the brainstem is a site of vulnerability to long-term effects of COVID-19, with persistent changes evident in the months after hospitalization,’ the authors of the study conclude.”

Signs of brain inflammation were present up to 18 months after first contracting the SARS-CoV-2 virus. if ('undefined' !== typeof window.tmntag && 'undefined' !== typeof window.tmntag.cmd) { tmntag.cmd.push(function () { tmntag.adTag('Purch_Y_C_0_2', false); }); } "We show that the brainstem is a site of vulnerability to long-term effects of COVID-19, with persistent changes evident in the months after hospitalization," the authors of the study conclude.
·sciencealert.com·
We Just Got More Evidence That Long COVID Is a Brain Injury
A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome
A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome
“A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome”
A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome
·nature.com·
A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome