Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms: A pilot study | PLOS One
Cognitive Slowing, Dysfunction in Verbal Working Memory, Divided Attention and Response Inhibition in Post COVID-19 Condition in Young Adults
The present study revealed that in YOUNG adults, university students, without other comorbidities, there can be significant long-lasting cognitive impairments TWO YEARS after COVID-19 infection."
➡️"Specifically, verbal working memory was significantly impaired, and a lower performance was detected in divided attention and response inhibition.”
Scientists find two brain biomarkers in long COVID sufferers that may be causing cognitive issues
“A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.”
A new study that is the first to compare inflammation and brain stress responses in long COVID-19 patients with individuals who have fully recovered shows that those with continued brain fog and other cognitive issues have a lower ability to adapt to stress and higher levels of inflammation in their brains.
Jess 🇨🇦 (@MeetJess) on X
Repeat COVID Infections & Dementia
A time bomb no one wants to talk about 🧵
Altered brain glucose metabolism in COVID-19 disease: an activation likelihood estimation meta-analysis of PET studies - PubMed
Radical Centrist,wrathful tantric deity🇺🇦🇹🇼🎗️ (@RadCentrism) on X
“Weird. If only some people discussed this 4-5 years ago…”
Is Covid Rewriting the Rules of Aging? Brain Decline Alarms Doctors
“Millions of long-Covid patients continue to struggle with cognitive difficulties”
Millions of long-Covid patients continue to struggle with cognitive difficulties
How COVID Impacts the Brain: Danielle Beckman and David Joffe
“How does COVID-19 impact the brain? Neuroscientist Danielle Beckman and expert David Joffe discuss direct neuronal effects and sleep disorders in Long COVID patients, and the importance of thorough evaluations for accurate diagnoses.”
Brain 18F-FDG PET imaging in outpatients with post-COVID-19 conditions: findings and associations with clinical characteristics
“Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.”
Outpatients with post-COVID-19 conditions exhibited extensive hypometabolic right fronto-temporal clusters. Patients with more numerous symptoms during the initial phase and with a longer duration of symptoms were at higher risk of persistent brain involvement.
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Exploring the Persistence of the Spike Protein along the Skull-Meninges-Brain Axis and the Neurological Effects of COVID-19
This analysis is supported by numerous videos and illustrations.
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
“Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review”
Post-COVID-19 Small Fiber Neuropathy as a New Emerging Quality of Life-Threatening Disease: A Systematic Review
Large hippocampus detected in Long COVID and ME/CFS patients - Griffith News
Alzheimer’s disease-like changes in COVID-19
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
Neurological syndromes associated with COVID-19: a multicenter study in Brazil - BMC Infectious Diseases
“197 patients were included, presenting with vascular syndromes (81), encephalopathy (68), encephalitis (19), Guillain-Barré syndrome (13), other neuropathies (12), and myelitis (4). The incidence curve of neurocovid mirrored that of COVID-19. Neurological syndromes were present regardless of COVID-19 severity. The median time from COVID-19 to onset of neurological symptoms was 14 days, suggesting a post-infectious immune-mediated mechanism.”
Clinical and radiological characteristics and 1-year self-reported outcomes from patients with encephalitis and coronavirus disease 2019 - Journal of Medical Case Reports
The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline
“The Impact of the COVID-19 Pandemic on Dementia Risk: Potential Pathways to Cognitive Decline”
Long Covid ‘changes brains of people differently to those who recover from virus’
“Long Covid ‘changes brains of people differently to those who recover from virus’
More than two million people in the UK are thought to be suffering from long Covid”
As many as 10-25% of people who get Covid will get Long Covid.
Long Covid ‘changes brains of people differently to those who recover from virus’More than two million people in the UK are thought to be suffering from long Covid
COVID-19 will never be like the Flu. Never.
“I have spent hundreds of hours in the microscope looking at the worst viruses can do to the brain, including the Zika virus, HIV, Flu, and others. I've never seen the type of damage SARS-CoV-2 leaves behind after infection with other viruses. “
Long COVID Breakthrough: Spike Proteins Persist in Brain for Years
“A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein.”
A study reveals that the spike protein of SARS-CoV-2 remains in the brain long after infection, causing potential neurological issues and accelerated brain aging. mRNA vaccines help lower this risk but are not completely effective in eliminating the protein.
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests
“Post-Covid cognitive impairment affects daily function and quality of life. • ACE-III fails to detect cognitive impairment in most post-Covid patients. • 89% of patients have impaired attention, executive function, processing speed on novel tests. • New tests are needed for post-Covid cognitive assessment in clinical practice.”
Post-Covid cognitive impairment affects daily function and quality of life.•ACE-III fails to detect cognitive impairment in most post-Covid patients.•89% of patients have impaired attention, executive function, processing speed on novel tests.•New tests are needed for post-Covid cognitive assessment in clinical practice.
What We Know About Covid’s Impact on Your Brain?
Brain shrinkage is observed even in mild or asymptomatic cases of Covid and impacts cognition.
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
“COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students”
“37 % of the undergraduates exhibited impaired cognition up to 17 months post-infection.”
COVID & the BRAIN… a thread 🧵
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
“Using the golden hamster as a model, we provide further evidence that SARS-CoV-2 is neuroinvasive and can persist in the central nervous system, as we found viral RNA and replicative virus in the brainstem after 80 days of infection.”
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Older adults recovering from COVID-19 face a 58% higher risk of developing dementia compared to those uninfected, with rates peaking 12 months post-infection.
Study reviewed 11 studies, 940k cases, 6.8M controls.
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
“The study shows that the SARS-CoV-2 spike protein remains in the brain's protective layers, the meninges, and the skull's bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases.”
The study shows that the SARS-CoV-2 spike protein remains in the brain's protective layers, the meninges, and the skull's bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases.
Video showing accumulation of spike protein (red) in skull bone marrow from a patient who died from Covid
Video showing accumulation of spike protein (red) in skull bone marrow from a patient who died from Covid