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Multimodal MRI analysis of COVID-19 effects on pediatric brain
Multimodal MRI analysis of COVID-19 effects on pediatric brain

Even mild Covid changes children’s brains.

“We speculate that viral-triggered neuroinflammation and immune response contribute to neurotoxic damage in brain regions involved in cognitive processing, ultimately resulting in alterations in cortical morphology and glymphatic function.”

We speculate that viral-triggered neuroinflammation and immune response contribute to neurotoxic damage in brain regions involved in cognitive processing, ultimately resulting in alterations in cortical morphology and glymphatic function.
#kids#brain#neuroimaging#brain changes#young people#brain inflammation#brain injury#cortical morphology#neurological#glymphatic clearance#cognition#cognitive decline#memory loss#brain abnormalities#neurodegeneration#Immune dysregulation#Immune Deficiency
·nature.com·
Multimodal MRI analysis of COVID-19 effects on pediatric brain
2025
2025

University of Texas researchers found that Omicron BA.1 caused lasting neurological issues in hACE2 mice, linked to blood-brain barrier breakdown, clotting, and inflammation.

Viral RNA and spike protein lingered in the brain even without live virus.

#brain#spike protein#neurodegeneration#neurologic changes
·t.co·
2025
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle‐Age Adults
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle‐Age Adults
“Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults”
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle-Age Adults
#Brain#neurodegeneration#neurologic changes#neurological#brain fog#young people#Memory#executive function#working memory
·onlinelibrary.wiley.com·
Neurologic Manifestations of Long COVID Disproportionately Affect Young and Middle‐Age Adults
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion

SARS-CoV-2 and HSV-1 induce amyloid aggregation, depleting soluble proteins.

Suggests a link between viral infections and neurodegenerative diseases via protein loss.

#Brain#Post-Acute Conditions#Amyloid#neurodegeneration#Neurodegenerative#Alzheimers#neurologic changes#neurological#amyloid aggregation
·pubs.acs.org·
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
COVID and the brain: researchers zero in on how damage occurs
COVID and the brain: researchers zero in on how damage occurs

SARS-CoV-2 preferentially infects astrocytes, which support neuron function, potentially leading to symptoms like fatigue and confusion.

SARS-CoV-2 can also infect pericytes, leading to restricted blood flow and small-vessel strokes.

#Brain#brain injury#astrocytes#small vessel strokes#Stroke#pericytes#restricted blood flow#vascular#neural loss#neurodegeneration
·nature.com·
COVID and the brain: researchers zero in on how damage occurs
SARS-CoV-2 Invasion and Pathological Links to Prion Disease
SARS-CoV-2 Invasion and Pathological Links to Prion Disease

Nearly half of those infected with SARS-CoV-2 experience long-term neurological problems, including brain fog and memory issues.

An infection may accelerate or exacerbate prion diseases like Creutzfeldt–Jakob disease, leading to rapid neurodegeneration.

#Prion#brain injury#Brain#Creutzfeldt-Jakob#neurodegeneration#brain fog#neurologic changes#neurological#Post-Acute Conditions#Long Covid#executive function#working memory#emotional challenges#emotional lability#emotional regulation deficits
·mdpi.com·
SARS-CoV-2 Invasion and Pathological Links to Prion Disease