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Thread by @JamesThrot on Thread Reader App
Thread by @JamesThrot on Thread Reader App

“Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵”

Let’s talk about COVID, brain damage & society. Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences? This thread is for the skeptics. I’m a neurologist, stay with me 🧵
·threadreaderapp.com·
Thread by @JamesThrot on Thread Reader App
Human challenge study reveals lasting cognitive decline after mild COVID-19
Human challenge study reveals lasting cognitive decline after mild COVID-19

“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
·news-medical.net·
Human challenge study reveals lasting cognitive decline after mild COVID-19
Thread by @Becca_Roth on Thread Reader App
Thread by @Becca_Roth on Thread Reader App
“Crying reading young ppl in TikTok comments discover in real time that they have brain damage from past covid infections. No one’s ever told them that it’s connected and they’re panicking because they’ve had Covid so many times. So heartbroken and angry that we’ve let this happen”
Crying reading young ppl in TikTok comments discover in real time that they have brain damage from past covid infections. No one’s ever told them that it’s connected and they’re panicking because they’ve had Covid so many times. So heartbroken and angry that we’ve let this happen
·threadreaderapp.com·
Thread by @Becca_Roth on Thread Reader App
Lacking focus, tired always? Could be brain fog
Lacking focus, tired always? Could be brain fog

“Brain fog may gradually evolve into a slight memory problem, difficulty finding the right word for things, objects, situations and then registering new information.”

A widely held notion is that SARS2 activates our immune systems, causing an inflammatory response in the brain.

·newindianexpress.com·
Lacking focus, tired always? Could be brain fog
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
Egyptian researchers analyzed data from over 4 million people and found that nearly 1 in 3 COVID-19 survivors face long-term cognitive or memory problems, while 43% experience persistent fatigue, revealing a major mental health burden from long COVID.
·bmcneurol.biomedcentral.com·
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients - BMC Neurology
How COVID Impacts the Brain: Danielle Beckman and David Joffe
How COVID Impacts the Brain: Danielle Beckman and David Joffe
“How does COVID-19 impact the brain? Neuroscientist Danielle Beckman and expert David Joffe discuss direct neuronal effects and sleep disorders in Long COVID patients, and the importance of thorough evaluations for accurate diagnoses.”
·youtube.com·
How COVID Impacts the Brain: Danielle Beckman and David Joffe
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
·nature.com·
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
·academic.oup.com·
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
·x.com·
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests

“Post-Covid cognitive impairment affects daily function and quality of life. • ACE-III fails to detect cognitive impairment in most post-Covid patients. • 89% of patients have impaired attention, executive function, processing speed on novel tests. • New tests are needed for post-Covid cognitive assessment in clinical practice.”

Post-Covid cognitive impairment affects daily function and quality of life.•ACE-III fails to detect cognitive impairment in most post-Covid patients.•89% of patients have impaired attention, executive function, processing speed on novel tests.•New tests are needed for post-Covid cognitive assessment in clinical practice.
·sciencedirect.com·
Clinic evaluation of cognitive impairment in post-COVID syndrome: Performance on legacy pen-and-paper and new digital cognitive tests
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students

“COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students”

“37 % of the undergraduates exhibited impaired cognition up to 17 months post-infection.”

·sciencedirect.com·
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics

Older adults recovering from COVID-19 face a 58% higher risk of developing dementia compared to those uninfected, with rates peaking 12 months post-infection.

Study reviewed 11 studies, 940k cases, 6.8M controls.

·bmcgeriatr.biomedcentral.com·
Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Worse, most people don’t even notice it has happened to themselves.
Worse, most people don’t even notice it has happened to themselves.

“Worse, most people don’t even notice it has happened to themselves.

But I can tell you we who continue to mask and have many fewer COVID infections can see the growing cognitive damage in more and more people around us.

Memory problems, like recall and word finding delays. Weakness and fatigue and motor control impairment. Growing executive function and emotional regulation deficits.

More and more friends disables and forced out of work or school by Long COVID symptoms.

It’s scary to witness the broad societal decline, and dispiriting to see so many governments and Public Health agencies persist in minimizing the growing problem.”

·x.com·
Worse, most people don’t even notice it has happened to themselves.
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment

Covid itself causes cognitive impairment. From 2020, prior to Covid vaccination of any kind:

“In our cohort of COVID-19 patients neurologic manifestations were frequent, including cognitive impairment.”

·sciencedirect.com·
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment
COVID survivors may develop dementia
COVID survivors may develop dementia

“COVID-19 survivors show signs of significant cognitive deficits which could become dementia even a year after having the virus.. The team [in India] found that more than 80% of people tested reported at least one of four symptoms – depression, anxiety, stress and insomnia – ranging from mild to severe.. At least 6.1% of the patients were diagnosed with mild cognitive impairment and 4% developed dementia. More than 60% of the patients experienced a loss of taste and smell during the active phase of the infection. This could alter the function of brain areas linked to cognitive ability and emotional well-being.."

COVID-19 survivors show signs of significant cognitive deficits which could become dementia even a year after having the virus1. They also have an increased risk of depression, anxiety and disrupted sleep.
·nature.com·
COVID survivors may develop dementia