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SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion

SARS-CoV-2 and HSV-1 induce amyloid aggregation, depleting soluble proteins.

Suggests a link between viral infections and neurodegenerative diseases via protein loss.

#Brain#Post-Acute Conditions#Amyloid#neurodegeneration#Neurodegenerative#Alzheimers#neurologic changes#neurological#amyloid aggregation
·pubs.acs.org·
SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion
COVID and the brain: researchers zero in on how damage occurs
COVID and the brain: researchers zero in on how damage occurs

SARS-CoV-2 preferentially infects astrocytes, which support neuron function, potentially leading to symptoms like fatigue and confusion.

SARS-CoV-2 can also infect pericytes, leading to restricted blood flow and small-vessel strokes.

#Brain#brain injury#astrocytes#small vessel strokes#Stroke#pericytes#restricted blood flow#vascular#neural loss#neurodegeneration
·nature.com·
COVID and the brain: researchers zero in on how damage occurs
SARS-CoV-2 Invasion and Pathological Links to Prion Disease
SARS-CoV-2 Invasion and Pathological Links to Prion Disease

Nearly half of those infected with SARS-CoV-2 experience long-term neurological problems, including brain fog and memory issues.

An infection may accelerate or exacerbate prion diseases like Creutzfeldt–Jakob disease, leading to rapid neurodegeneration.

#Prion#brain injury#Brain#Creutzfeldt-Jakob#neurodegeneration#brain fog#neurologic changes#neurological#Post-Acute Conditions#Long Covid#executive function#working memory#emotional challenges#emotional lability#emotional regulation deficits
·mdpi.com·
SARS-CoV-2 Invasion and Pathological Links to Prion Disease