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COVID-19 infection associated with increased risk of new-onset vascular dementia in older adults
COVID-19 infection associated with increased risk of new-onset vascular dementia in older adults
COVID-19 infection linked to a 41% higher risk of developing new-onset vascular dementia in older adults, with researchers warning that the virus may have lasting effects on brain and vascular health even after recovery.
#Cognitive Impairment#cognition#cognitive decline#dementia#neurologic changes#vascular dementia#vascular#vascular aging#Post-Acute Conditions
·cidrap.umn.edu·
COVID-19 infection associated with increased risk of new-onset vascular dementia in older adults
COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years
COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years
UK Biobank study of 54,757 adults aged 50+ found that COVID-19 survivors had a 41% higher risk of dementia and a 77% higher risk of vascular dementia after two years, especially in those unvaccinated or with mental illness.
#dementia#vascular#long covid#Cognitive Impairment#cognitive decline#cognition#neurologic changes#vascular dementia
·nature.com·
COVID-19 infection associated with increased risk of new-onset vascular dementia in adults ≥50 years
A Peripheral Neuron-to-Microglia Signaling Axis Connecting Transient Viral Infection to Persistent Neuroinflammatory States | Research Square
A Peripheral Neuron-to-Microglia Signaling Axis Connecting Transient Viral Infection to Persistent Neuroinflammatory States | Research Square

How does a transient viral infection like COVID lead to long lasting neurologic symptoms?

In humans and in animal models, SARS-CoV-2 can damage peripheral sensory nerves in the nose, leaving behind debris that can then trigger inflammation in brain microglia for weeks to months after infection, which can then lead to post-viral neurological symptoms like cognitive dysfunction (brain fog).

The peripheral neuron-to-microglia axis offers a potential explanation for persistent inflammation seen in conditions like Long COVID and ME/CFS.

#Long Covid#Neuroinflammation#Post-Acute Conditions#neurologic changes#neurological#inflammation#microglia#Nerves#Cognitive Impairment
·researchsquare.com·
A Peripheral Neuron-to-Microglia Signaling Axis Connecting Transient Viral Infection to Persistent Neuroinflammatory States | Research Square