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Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
“Using the golden hamster as a model, we provide further evidence that SARS-CoV-2 is neuroinvasive and can persist in the central nervous system, as we found viral RNA and replicative virus in the brainstem after 80 days of infection.”
#Long Covid#Brain#Post-Acute Conditions#Neurodegenerative#Brainstem#Hamster Model#Viral Persistence#depression#memory loss#memory#central nervous system#anxiety
·biorxiv.org·
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
SARS-CoV-2 infection in microglia and its sequelae: What do we know so far?
SARS-CoV-2 infection in microglia and its sequelae: What do we know so far?

“SARS-CoV-2 may infect CNS, affecting microglia and brain cells. • Neuroinflammation from SARS-CoV-2 could lead to long COVID memory issues.”

SARS-CoV-2 may infect CNS, affecting microglia and brain cells.•Neuroinflammation from SARS-CoV-2 could lead to long COVID memory issues.
#Brain#Neuroinflammation#microglia#cognition#cognitive decline#Memory#memory loss#Viral Persistence
·sciencedirect.com·
SARS-CoV-2 infection in microglia and its sequelae: What do we know so far?
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
“The study shows that the SARS-CoV-2 spike protein remains in the brain's protective layers, the meninges, and the skull's bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases.”
The study shows that the SARS-CoV-2 spike protein remains in the brain's protective layers, the meninges, and the skull's bone marrow for up to four years after infection. This persistent presence of the spike protein could trigger chronic inflammation in affected individuals and increase the risk of neurodegenerative diseases.
#Long Covid#Brain#Neuroinflammation#Cognitive Impairment#Viral Persistence#Post-Acute Sequelae of COVID-19#spike protein#meninges#cognition
·medicalxpress.com·
Long COVID: SARS-CoV-2 spike protein accumulation linked to long-lasting brain effects
Eric Topol on Twitter
Eric Topol on Twitter
Important new report on #LongCovid and the brain demonstrating persistence of the virus spike protein, throughout the body and particularly the skull-meninges axis, both in humans and the mouse model
#Viral Persistence#spike protein#Brain
·twitter.com·
Eric Topol on Twitter
Ali M. Erturk on Twitter
Ali M. Erturk on Twitter

60% of us who had COVID still might have lingering viral spikes in our heads! Our new study reveals SARS-CoV-2 spike accumulation in the skull-meninges-brain axis & its implications in long COVID. By @zhouyi_rong

@HongchengM

@Sakethkapoor 🔬🧠🦠🧵👇

#Brain#spike protein#Viral Persistence
·twitter.com·
Ali M. Erturk on Twitter