Clinical and radiological characteristics and 1-year self-reported outcomes from patients with encephalitis and coronavirus disease 2019 - Journal of Medical Case Reports
COVID-19 will never be like the Flu. Never.
“I have spent hundreds of hours in the microscope looking at the worst viruses can do to the brain, including the Zika virus, HIV, Flu, and others. I've never seen the type of damage SARS-CoV-2 leaves behind after infection with other viruses. “
A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome
“A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome”
A case-control study of reaction time deficits in a 3D virtual reality in patients with Post-COVID syndrome
MRI scans reveal the damage long Covid does to your brain
“MRI scans reveal the damage long Covid does to your brain
Researchers suggested lasting Covid symptoms might be an indirect effect of brainstem inflammatory injury”
Cognitive and psychiatric symptom trajectories 2–3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK
“Participants had worse cognitive scores than would be expected on the basis of their sociodemographic characteristics across all cognitive domains tested (average score 0·71 SD below the mean [IQR 0·16–1·04]; p<0·0001). Most participants reported at least mild depression (263 [74·5%] of 353), anxiety (189 [53·5%] of 353), fatigue (220 [62·3%] of 353), or subjective cognitive decline (184 [52·1%] of 353), and more than a fifth reported severe depression (79 [22·4%] of 353), fatigue (87 [24·6%] of 353), or subjective cognitive decline (88 [24·9%] of 353). Depression, anxiety, and fatigue were worse at 2–3 years than at 6 months or 12 months, with evidence of both worsening of existing symptoms and emergence of new symptoms. Symptoms at 2–3 years were not predicted by the severity of acute COVID-19 illness, but were strongly predicted by the degree of recovery at 6 months”
Participants had worse cognitive scores than would be expected on the basis of their sociodemographic characteristics across all cognitive domains tested (average score 0·71 SD below the mean [IQR 0·16–1·04]; p<0·0001). Most participants reported at least mild depression (263 [74·5%] of 353), anxiety (189 [53·5%] of 353), fatigue (220 [62·3%] of 353), or subjective cognitive decline (184 [52·1%] of 353), and more than a fifth reported severe depression (79 [22·4%] of 353), fatigue (87 [24·6%] of 353), or subjective cognitive decline (88 [24·9%] of 353). Depression, anxiety, and fatigue were worse at 2–3 years than at 6 months or 12 months, with evidence of both worsening of existing symptoms and emergence of new symptoms. Symptoms at 2–3 years were not predicted by the severity of acute COVID-19 illness, but were strongly predicted by the degree of recovery at 6 months
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
EXTREME and incomplete oversimplification of the many complex neurological issues caused by SarsCov2, but important facet of the vaguely defined “brain fog” of Long Covid and post-acute Covid lingering symptoms.
“Neurological symptoms have been widely observed in COVID-19 patients, with many survivors exhibiting persistent neurological and cognitive impairment. New research from the University of Minnesota found that COVID-19 triggers inflammation in the brain, which is linked to many COVID-related symptoms such as fatigue and ‘brain fog.’”