Comprehensive mapping of the signaling events evoked by SARS-CoV-2 variants delta and omicron in human astrocytes
Thread by @ZdenekVrozina on Thread Reader App
“A new study strengthens the view that SARS-CoV-2: disrupts brain homeostasis, alters ionic & neurotransmitter balance, and triggers lasting epigenetic reprogramming. Researchers exposed human primary astrocytes to Delta and Omicron. The results are striking🧵”
A new study strengthens the view that SARS-CoV-2:
disrupts brain homeostasis,
alters ionic & neurotransmitter balance,
and triggers lasting epigenetic reprogramming.
Researchers exposed human primary astrocytes to Delta and Omicron.
The results are striking🧵
Thread by @IntegralAnswers on Thread Reader App
“Thread: A molecular clue to Long COVID “brain fog”
1/ New study from Yokohama City Univ used PET imaging of AMPA receptors. Long COVID patients showed elevated AMPAR levels, linked to both cognitive impairment and inflammation. A molecular biomarker emerges.”
Thread: A molecular clue to Long COVID “brain fog”
1/ New study from Yokohama City Univ used PET imaging of AMPA receptors. Long COVID patients showed elevated AMPAR levels, linked to both cognitive impairment and inflammation. A molecular biomarker emerges.
Thread by @ZdenekVrozina on Thread Reader App
“COVID and brain fog. For millions, it’s the most disabling legacy of the pandemic. Now, a new brain imaging study reveals a clear biological basis - and the parallels with other diseases are not encouraging.🧵”
COVID and brain fog.
For millions, it’s the most disabling legacy of the pandemic.
Now, a new brain imaging study reveals a clear biological basis - and the parallels with other diseases are not encouraging.🧵
Molecular Imaging Findings on Acute and Long-Term Effects of COVID-19 on the Brain: A Systematic Review
“Molecular imaging techniques such as PET and SPECT have been used to shed light on how coronavirus disease 2019 (COVID-19) affects the human brain. We provide a systematic review that summarizes the current literature according to 5 predominant topics.”
Molecular imaging techniques such as PET and SPECT have been used to shed light on how coronavirus disease 2019 (COVID-19) affects the human brain. We provide a systematic review that summarizes the current literature according to 5 predominant topics.
New study reveals molecular basis of Long COVID brain fog
“the researchers found a notable and widespread increase in the density of AMPARs across the brains of patients. This elevated receptor density was directly correlated with the severity of their cognitive impairment, suggesting a clear link between these molecular changes and the symptoms. Additionally, the concentrations of various inflammatory markers were also correlated with AMPAR levels, indicating a possible interaction between inflammation and receptor expression.”