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Doctors struggle to treat long Covid patients in India; researchers point to inadequate studies
Doctors struggle to treat long Covid patients in India; researchers point to inadequate studies

Dr. Arun Garg (The Medicity, Gurugram, India) said, "[I notice] a spike in stroke cases among young patients not suffering from known risk factors such as diabetes, hypertension and obesity.. Similarly, we are seeing more cases of encephalopathy, swelling of the brain, without reason and having a confused state of mind following one or two days of fever. Their MRI scans show no changes. These patients have increased significantly after Covid.. [Currently,] Other than routine blood tests that measure inflammation, we do antibody tests to look for direct markers. In many of these patients, we are finding rare antibodies which are very new to us and were not there pre-Covid."

#Stroke#encephalopathy#brain inflammation#brain#inflammation#antibodies#cognition#cognitive decline#confusion
·thehindu.com·
Doctors struggle to treat long Covid patients in India; researchers point to inadequate studies
Pioneering discovery and therapeutics at the brain-vascular-immune interface
Pioneering discovery and therapeutics at the brain-vascular-immune interface

A new paper in Cell, “Pioneering discovery and therapeutics at the brain-vascular-immune interface,” describes COVID-19 as a neurological disease alongside multiple sclerosis, Alzheimer’s, stroke and traumatic brain injury.

“COVID-19 can accelerate progression of dementia and induce BBB disruption and inflammatory blood clots causally linked with neuroinflammation and neuronal loss.8 In neurodevelopmental disorders, prematurity and perinatal hypoxia that trigger brain hemorrhage and BBB disruption are risk factors for cerebral palsy, intellectual disability, and autism. Collectively, these risk factors highlight the interconnected vascular and immune triggers of neurological diseases.”

#brain#brain-vascular-immune interface#neurologic changes#neurological#vascular#immune dysregulation#brain injury#inflammation#brain inflammation#blood brain barrier#Neuroinflammation#neural loss#dementia#autism#blood clots#brain hemorrhage#cerebral blood flow#cognition#cognitive decline
·cell.com·
Pioneering discovery and therapeutics at the brain-vascular-immune interface
Severe Covid infections can inflame brain’s ‘control centre’, research says
Severe Covid infections can inflame brain’s ‘control centre’, research says
“Severe Covid infections can drive inflammation in the brain’s ‘control centre’ researchers say, leading to damage that may explain the long-term breathlessness, fatigue and anxiety some patients experience.
#brain#brain injury#brain control centre#breathing#fatigue#Anxiety#neuroimaging#neurological#inflammation#Neuroinflammation#cognition#brainstem
·theguardian.com·
Severe Covid infections can inflame brain’s ‘control centre’, research says
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment
Covid can disrupt the blood brain barrier, the shield that protects the nervous system making it ‘leaky’.
#cognition#blood flow#blood brain barrier#brain#brain injury#brain inflammation#Neuroinflammation#inflammation
·nature.com·
Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment