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Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
“We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease”
We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease
#Brain#cognition#brain injury#Neuroinflammation#Post-Acute Conditions#neurological#Parkinsons#Alzheimers
·nature.com·
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
Emerging signs of Alzheimer‐like tau hyperphosphorylation and neuroinflammation in the brain post recovery from COVID‐19
Emerging signs of Alzheimer‐like tau hyperphosphorylation and neuroinflammation in the brain post recovery from COVID‐19
Emerging signs of Alzheimer’s-like pathology in brains if people recovered from COVID-19, even though no direct SARS-CoV-2 invasion was detected
#Alzheimers#cognition#cognitive decline#memory#memory loss#long covid#Post-Acute Conditions#brain#brain injury
·onlinelibrary.wiley.com·
Emerging signs of Alzheimer‐like tau hyperphosphorylation and neuroinflammation in the brain post recovery from COVID‐19
Kentucky research links long COVID brain fog to Alzheimer’s | Lexingt…
Kentucky research links long COVID brain fog to Alzheimer’s | Lexingt…
“Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.”
Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.
#Alzheimers#brain#brain injury#Memory#memory loss#Post-Acute Conditions
·archive.is·
Kentucky research links long COVID brain fog to Alzheimer’s | Lexingt…
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Non paywall version of catalogued Bloomberg article
Scientists are worried that persisting cognitive issues may signal a coming surge of dementia and other mental conditions
#brain#brain injury#brain atrophy#dementia#Alzheimers#Memory#memory loss#brain fog#Post-Acute Conditions#long covid#fatigue#cognition#cognitive decline#Neuroinflammation#Immune system#immune dysregulation#T cells#Parkinsons#IQ
·archive.is·
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Parallel electrophysiological abnormalities due to COVID‐19 infection and to Alzheimer's disease and related dementia
Parallel electrophysiological abnormalities due to COVID‐19 infection and to Alzheimer's disease and related dementia
“Resting-state EEG abnormalities include EEG slowing (reduced alpha rhythm; increased slow waves) and epileptiform activity. An expert panel conducted a systematic review to present compelling evidence that cognitive deficits due to COVID-19 and to Alzheimer's disease and related dementia (ADRD) are driven by overlapping pathologies and neurophysiological abnormalities. EEG abnormalities seen in COVID-19 patients resemble those observed in early stages of neurodegenerative diseases, particularly ADRD”
#Alzheimers#dementia#cognition#brain injury#Memory#memory loss
·alz-journals.onlinelibrary.wiley.com·
Parallel electrophysiological abnormalities due to COVID‐19 infection and to Alzheimer's disease and related dementia
UK researchers find Alzheimer’s-like brain changes in long COVID patients
UK researchers find Alzheimer’s-like brain changes in long COVID patients
“New research from the University of Kentucky’s Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen in Alzheimer’s disease and related dementias.”
#dementia#Alzheimers#long covid#brain#brain injury#Post-Acute Conditions#Memory#memory loss
·uknow.uky.edu·
UK researchers find Alzheimer’s-like brain changes in long COVID patients
Does Long COVID Lead to Alzheimer's? A New Study Took an Unexpected Turn
Does Long COVID Lead to Alzheimer's? A New Study Took an Unexpected Turn
“More than one in ten people who catch COVID don’t fully recover — developing a chronic condition called Long COVID which causes a variety of debilitating symptoms, including brain fog. Since some studies have found that COVID infections are associated with overall brain shrinkage, altered brain structure, and an increased risk of developing Alzheimer’s, researchers have been investigating the links between COVID and Alzheimer’s.”
More than one in ten people who catch COVID don’t fully recover — developing a chronic condition called Long COVID which causes a variety of debilitating symptoms, including brain fog. Since some studies have found that COVID infections are associated with overall brain shrinkage, altered brain structure, and an increased risk of developing Alzheimer’s, researchers have been investigating the links between COVID and Alzheimer’s.
#Alzheimers#brain#brain injury#dementia#long covid#Post-Acute Conditions
·beingpatient.com·
Does Long COVID Lead to Alzheimer's? A New Study Took an Unexpected Turn