Association between COVID-19 infection and new-onset dementia in older adults: a systematic review and meta-analysis - BMC Geriatrics
Older adults recovering from COVID-19 face a 58% higher risk of developing dementia compared to those uninfected, with rates peaking 12 months post-infection.
Study reviewed 11 studies, 940k cases, 6.8M controls.
Frontiers | Frequency of Neurological Diseases After COVID-19, Influenza A/B and Bacterial Pneumonia
A study of electronic medical records of 35,362 COVID-19 outpatients in Denmark showed an increased relative risk (RR) of 3.5 for Alzheimer's disease and 2.6 for Parkinson's disease compared to outpatients who did not have COVID-19.
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
“We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease”
We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease
Long COVID patients have similar brain activity to those with dementia, UK researchers find
“Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.”
Kentucky research links long COVID brain fog to Alzheimer’s | Lexingt…
“Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.”
Some patients with COVID see similar brain changes to people with such neurodegenerative disorders as Alzheimer’s, according to University of Kentucky researchers.
Alzheimer's-like brain changes found in long COVID patients
“New research from the University of Kentucky's Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen in Alzheimer's disease and related dementias.”
UK researchers find Alzheimer’s-like brain changes in long COVID patients
“New research from the University of Kentucky’s Sanders-Brown Center on Aging shows compelling evidence that the cognitive impairments observed in long COVID patients share striking similarities with those seen in Alzheimer’s disease and related dementias.”
Does Long COVID Lead to Alzheimer's? A New Study Took an Unexpected Turn
“More than one in ten people who catch COVID don’t fully recover — developing a chronic condition called Long COVID which causes a variety of debilitating symptoms, including brain fog. Since some studies have found that COVID infections are associated with overall brain shrinkage, altered brain structure, and an increased risk of developing Alzheimer’s, researchers have been investigating the links between COVID and Alzheimer’s.”
More than one in ten people who catch COVID don’t fully recover — developing a chronic condition called Long COVID which causes a variety of debilitating symptoms, including brain fog. Since some studies have found that COVID infections are associated with overall brain shrinkage, altered brain structure, and an increased risk of developing Alzheimer’s, researchers have been investigating the links between COVID and Alzheimer’s.
