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Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
“We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease”
We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease
#Brain#cognition#brain injury#Neuroinflammation#Post-Acute Conditions#neurological#Parkinsons#Alzheimers
·nature.com·
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…
Non paywall version of catalogued Bloomberg article
Scientists are worried that persisting cognitive issues may signal a coming surge of dementia and other mental conditions
#brain#brain injury#brain atrophy#dementia#Alzheimers#Memory#memory loss#brain fog#Post-Acute Conditions#long covid#fatigue#cognition#cognitive decline#Neuroinflammation#Immune system#immune dysregulation#T cells#Parkinsons#IQ
·archive.is·
Does Covid Lead to Dementia? Here's What the Virus May Have Done to Y…