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Thread by @JamesThrot on Thread Reader App
Thread by @JamesThrot on Thread Reader App

“Let’s talk about COVID, brain damage & society.

Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?

This thread is for the skeptics.

I’m a neurologist, stay with me 🧵”

Let’s talk about COVID, brain damage & society. Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences? This thread is for the skeptics. I’m a neurologist, stay with me 🧵
#Brain#Covid Isn't Over#Post-Acute Conditions#consequences#frontal lobe#brain dysfunction#cognition#cognitive decline#Long Covid#neurological#Post-Acute Sequelae of COVID-19#Cognitive Impairment#white matter#grey matter shrinkage#olfactory damage#working memory#Discussion#analysis#James Throt
·threadreaderapp.com·
Thread by @JamesThrot on Thread Reader App
Human challenge study reveals lasting cognitive decline after mild COVID-19
Human challenge study reveals lasting cognitive decline after mild COVID-19

“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
#cognitive decline#memory#long covid#cognition#Cognitive Impairment#Brain Fog#Long Covid#Post-Acute Conditions#Brain#neurological
·news-medical.net·
Human challenge study reveals lasting cognitive decline after mild COVID-19
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing
Cognitive decline is a common symptom of post-COVID-19 syndrome. However, the mechanisms underlying this deficit remain poorly understood. This study aims to investigate the relationship between brain metabolic and neurophysiological alteration patterns in patients with persistent subjective cognitive decline after mild COVID-19 using joint FDG-PET and EEG analyses.
Cognitive decline is a common symptom of post-COVID-19 syndrome. However, the mechanisms underlying this deficit remain poorly understood. This study aims to investigate the relationship between brain metabolic and neurophysiological alteration patterns in patients with persistent subjective cognitive decline after mild COVID-19 using joint FDG-PET and EEG analyses.
#Cognitive Impairment#brain changes#cognitive decline#hypometabolism#Post-Acute Conditions#brain dysfunction#brain#neuroimaging#EEG slowing#cognition
·nature.com·
Mapping brain changes in post-COVID-19 cognitive decline via FDG PET hypometabolism and EEG slowing
Expert warns common virus dramatically raises risk of early dementia
Expert warns common virus dramatically raises risk of early dementia
“Top scientists have warned that those who've had Covid may be at greater risk of developing dementia before they reach 70.”
Top scientists have warned that those who've had Covid may be at greater risk of developing dementia before they reach 70.
#dementia#Brain#cognitive decline#cognition#Memory#memory loss#consequences#Post-Acute Conditions#Alzheimers
·dailymail.co.uk·
Expert warns common virus dramatically raises risk of early dementia
How COVID Impacts the Brain: Danielle Beckman and David Joffe
How COVID Impacts the Brain: Danielle Beckman and David Joffe
“How does COVID-19 impact the brain? Neuroscientist Danielle Beckman and expert David Joffe discuss direct neuronal effects and sleep disorders in Long COVID patients, and the importance of thorough evaluations for accurate diagnoses.”
#Brain#Cognitive decline#Long Covid#Memory#neurodegeneration#brain#neuronal effects#sleep#sleep disturbances#David Joffe#video#Danielle Beckman#podcast
·youtube.com·
How COVID Impacts the Brain: Danielle Beckman and David Joffe
Multimodal MRI analysis of COVID-19 effects on pediatric brain
Multimodal MRI analysis of COVID-19 effects on pediatric brain

Even mild Covid changes children’s brains.

“We speculate that viral-triggered neuroinflammation and immune response contribute to neurotoxic damage in brain regions involved in cognitive processing, ultimately resulting in alterations in cortical morphology and glymphatic function.”

We speculate that viral-triggered neuroinflammation and immune response contribute to neurotoxic damage in brain regions involved in cognitive processing, ultimately resulting in alterations in cortical morphology and glymphatic function.
#kids#brain#neuroimaging#brain changes#young people#brain inflammation#brain injury#cortical morphology#neurological#glymphatic clearance#cognition#cognitive decline#memory loss#brain abnormalities#neurodegeneration#Immune dysregulation#Immune Deficiency
·nature.com·
Multimodal MRI analysis of COVID-19 effects on pediatric brain
newsGP - How COVID-19 leaves its mark on the brain
newsGP - How COVID-19 leaves its mark on the brain
“Mounting research shows the disease can lead to an array of problems, including significant drops in IQ scores, writes Dr Ziyad Al-Aly.”
Mounting research shows the disease can lead to an array of problems, including significant drops in IQ scores, writes Dr Ziyad Al-Aly.
#brain#cognition#Post-Acute Conditions#memory loss#brain changes#brain dysfunction#cognitive decline#neurological#Memory#IQ#Ziyad Al-Aly
·www1.racgp.org.au·
newsGP - How COVID-19 leaves its mark on the brain
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
#Ears#Post-Acute Conditions#Auditory System#Long Covid#Brain#PASC#neurological#long covid#hearing loss#tinnitus#Fatigue#ANA test#Depression#cognitive decline
·nature.com·
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
WTF DID SAM GET HIMSELF INTO?? | Hasanabi & Noah Kulwin React
WTF DID SAM GET HIMSELF INTO?? | Hasanabi & Noah Kulwin React
Starting at 4:15: “I’m becoming a bit of a Covid truther. I think we genuinely saw like an IQ drop across the board just of all the people who got hit with Covid. People’s brains I don’t think work as much or as well as they used to.”
#Discussion#Video#Brain#Covid History#brain injury#cognitive decline#cognitive disability#Cognitive Fatigue#Cognitive Impairment#cognition#working memory#IQ#anecdote
·youtube.com·
WTF DID SAM GET HIMSELF INTO?? | Hasanabi & Noah Kulwin React
SARS-CoV-2 affects Alzheimer’s disease
SARS-CoV-2 affects Alzheimer’s disease

"Patients suffering from COVID-19 have been found to exhibit dementia-related biomarkers.. The findings of this study suggest a potential link between mild-to-moderate SARS-CoV-2 infection and the initiation or acceleration of brain β-amyloid pathology, and hint at the possibility of an increased future incidence of Alzheimer’s disease subsequent to the COVID-19 pandemic."

#Alzheimers#Brain#Post-Acute Conditions#dementia#cognition#cognitive decline#Amyloid#Neuroinflammation#brain changes#brain injury
·nature.com·
SARS-CoV-2 affects Alzheimer’s disease
Understanding the Impact of COVID-19 on Personality and Brain Function: A Grim Reality or a Wake-Up Call?
Understanding the Impact of COVID-19 on Personality and Brain Function: A Grim Reality or a Wake-Up Call?
“A nightmare scenario would be if mankind were targeted by a pathogen that attacks our frontal lobes and changes our personalities. Such a pathogen could bring an end to society as we know it. Unfortunately, the nightmare may be real and taking shape in SARS-CoV-2.”
#Brain#cognition#brain injury#personality change#brain changes#brain dysfunction#cognitive decline
·infectioncontroltoday.com·
Understanding the Impact of COVID-19 on Personality and Brain Function: A Grim Reality or a Wake-Up Call?
We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time. The geopolitical ramifications of this are worrisome. I am in no doubt about what I’m seeing. The cause? Ceaseless SARS-CoV-2 infections pic.twitter.com/0X96poRxHJ— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) March 1, 2025
We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time. The geopolitical ramifications of this are worrisome. I am in no doubt about what I’m seeing. The cause? Ceaseless SARS-CoV-2 infections pic.twitter.com/0X96poRxHJ— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) March 1, 2025

“We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time.

The geopolitical ramifications of this are worrisome.

I am in no doubt about what I’m seeing.

The cause?

Ceaseless SARS-CoV-2 infections” A THREAD WITH STUDIES:

#Brain#brain dysfunction#cognition#cognitive decline#dementia#frontotemporal dementia#frontal lobe injury#ADHD#James Throt#Discussion#analysis
·x.com·
We are currently watching what I can only describe as the early stages of Frontotemporal Dementia on a mass scale playing out in real time. The geopolitical ramifications of this are worrisome. I am in no doubt about what I’m seeing. The cause? Ceaseless SARS-CoV-2 infections pic.twitter.com/0X96poRxHJ— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) March 1, 2025
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Structural brain changes in post-COVID condition and its relationship with cognitive impairment
#Brain#Brain shrinkage#brain atrophy#Long Covid#Post-Acute Conditions#cognitive decline#cognition#organ damage
·academic.oup.com·
Structural brain changes in post-COVID condition and its relationship with cognitive impairment | Brain Communications | Oxford Academic
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025

“Covid 19 is causing widespread brain damage on a global scale.

SARS-CoV-2 damages the brain. FACT.

Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation.

The signs are clear.

Signed, a neurologist

🧵”

#Brain#Discussion#Post-Acute Conditions#brain injury#brain dysfunction#cognition#cognitive decline#neurologic changes#neurological
·x.com·
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025
New neuroscience research shows COVID-19 leaves mark on young adult brains
New neuroscience research shows COVID-19 leaves mark on young adult brains
“A new study published in Brain, Behavior, and Immunity has found that young adults who have recovered from COVID-19 show distinct patterns of brain activity during cognitive tasks, even if they perform normally on those tasks. These brain activity changes are similar to those seen in much older adults and are particularly pronounced in individuals reporting ‘brain fog.’”
A new study published in Brain, Behavior, and Immunity has found that young adults who have recovered from COVID-19 show distinct patterns of brain activity during cognitive tasks, even if they perform normally on those tasks. These brain activity changes are similar to those seen in much older adults and are particularly pronounced in individuals reporting “brain fog.”
#Brain#young people#cognition#Cognitive Decline#brain abnormalities#brain injury#accelerated aging#Post-Acute Conditions
·psypost.org·
New neuroscience research shows COVID-19 leaves mark on young adult brains
I’ve spoken about this numerous times since Covid ate brain, but I’m now missing The Gift of Fear. Prior to my dramatic personality/cognitive changes, I had a highly evolved internal warning system that successfully kept me alive. Now I don’t care. It *could* be connected to…
I’ve spoken about this numerous times since Covid ate brain, but I’m now missing The Gift of Fear. Prior to my dramatic personality/cognitive changes, I had a highly evolved internal warning system that successfully kept me alive. Now I don’t care. It *could* be connected to…
“I’ve spoken about this numerous times since Covid ate brain, but I’m now missing The Gift of Fear. Prior to my dramatic personality/cognitive changes, I had a highly evolved internal warning system that successfully kept me alive. Now I don’t care. It could be connected to knowing nothing is going to be done since our country was hijacked by the 0.1% & deliberately broken long, long ago, & we all know everyone is going to reflexively blame The Other Side while Both Sides work together to fuck us over brunch. Why worry about things we’re going to pretend away?”
#brain#brain injury#Cognitive Decline#cognition#Laura Miers#Anecdote#Post-Acute Conditions
·x.com·
I’ve spoken about this numerous times since Covid ate brain, but I’m now missing The Gift of Fear. Prior to my dramatic personality/cognitive changes, I had a highly evolved internal warning system that successfully kept me alive. Now I don’t care. It *could* be connected to…
Does COVID increase the risk of Alzheimer’s disease?
Does COVID increase the risk of Alzheimer’s disease?
“Scientists discover that even mild COVID-19 can alter brain proteins linked to Alzheimer’s disease, potentially increasing dementia risk—raising urgent public health concerns.”
Scientists discover that even mild COVID-19 can alter brain proteins linked to Alzheimer’s disease, potentially increasing dementia risk—raising urgent public health concerns.
#Alzheimers#Brain#Memory#cognition#dementia#cognitive decline
·news-medical.net·
Does COVID increase the risk of Alzheimer’s disease?
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
#Brain#Cognition#cognitive decline#Cognitive decline#Brain fog#Neuroinflammation#Post-Acute Conditions#Long Covid#organ damage
·x.com·
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc

“The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc

An unparalleled horror show & crime.”

#Brain#Cognitive Decline#dementia#Parkinsons#Alzheimers#neurological#tinnitus#vertigo#Dana Parish#Discussion#Anecdote#compilations#brain dysfunction#brain injury#Post-Acute Conditions
·x.com·
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students

“COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students”

“37 % of the undergraduates exhibited impaired cognition up to 17 months post-infection.”

#Brain#cognition#brain injury#Long Covid#Memory#cognitive decline#Cognitive Impairment#brain haemodynamics#young people#undergraduate students
·sciencedirect.com·
COVID-19 may Enduringly Impact cognitive performance and brain haemodynamics in undergraduate students