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Multimodal MRI analysis of COVID-19 effects on pediatric brain
Multimodal MRI analysis of COVID-19 effects on pediatric brain

Even mild Covid changes children’s brains.

“We speculate that viral-triggered neuroinflammation and immune response contribute to neurotoxic damage in brain regions involved in cognitive processing, ultimately resulting in alterations in cortical morphology and glymphatic function.”

We speculate that viral-triggered neuroinflammation and immune response contribute to neurotoxic damage in brain regions involved in cognitive processing, ultimately resulting in alterations in cortical morphology and glymphatic function.
·nature.com·
Multimodal MRI analysis of COVID-19 effects on pediatric brain
newsGP - How COVID-19 leaves its mark on the brain
newsGP - How COVID-19 leaves its mark on the brain
“Mounting research shows the disease can lead to an array of problems, including significant drops in IQ scores, writes Dr Ziyad Al-Aly.”
Mounting research shows the disease can lead to an array of problems, including significant drops in IQ scores, writes Dr Ziyad Al-Aly.
·www1.racgp.org.au·
newsGP - How COVID-19 leaves its mark on the brain
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
“PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression.”
PASC subjects showed an increased prevalence of tinnitus and more perceived hearing handicaps despite matched peripheral hearing ability, in addition to increased cognitive fatigue, anxiety, and depression. ABR wave V latency differences between the slow and fast click r
·nature.com·
Altered auditory brainstem responses are post-acute sequela of SARS-CoV-2 (PASC)
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025

“Covid 19 is causing widespread brain damage on a global scale.

SARS-CoV-2 damages the brain. FACT.

Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation.

The signs are clear.

Signed, a neurologist

🧵”

·x.com·
Correct ✅ Covid 19 is causing widespread brain damage on a global scale. SARS-CoV-2 damages the brain. FACT. Brain fog, memory issues, more mistakes/crashes/accidents, less empathy, worsening mental health/emotional regulation. The signs are clear. Signed, a neurologist 🧵 https://t.co/CI5p3RsXBu pic.twitter.com/2yMIk966QA— James Throt MBBS, MD, PhD, FRCPath (@JamesThrot) February 14, 2025
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc

“The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc

An unparalleled horror show & crime.”

·x.com·
The widespread 🧠 neuro issues I’m witnessing can’t be overstated; a tipping point of previously healthy adults into early Parkinson’s/ GBS/ dementia/ ALS/ serious 👁️ issues/ strokes/ tremors/ vertigo / intractable anosmia & tinnitus etc
If you’re not noticing the (obvious) cognitive impairment in practically everyone around you, it may be due to your own cognitive decline.
If you’re not noticing the (obvious) cognitive impairment in practically everyone around you, it may be due to your own cognitive decline.

“If you’re not noticing the (obvious) cognitive impairment in practically everyone around you, it may be due to your own cognitive decline.

Or denial is rearing its ugly head once again.

Perhaps it’s easier for me considering my background, but honestly, it’s so bloody palpable.”

·x.com·
If you’re not noticing the (obvious) cognitive impairment in practically everyone around you, it may be due to your own cognitive decline.
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment

Covid itself causes cognitive impairment. From 2020, prior to Covid vaccination of any kind:

“In our cohort of COVID-19 patients neurologic manifestations were frequent, including cognitive impairment.”

·sciencedirect.com·
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment
COVID Linked to Lower IQ, Poor Memory and Other Negative Impacts on Brain Health
COVID Linked to Lower IQ, Poor Memory and Other Negative Impacts on Brain Health
“COVID-19 poses a serious risk to brain health, even in mild cases, and the effects are now being revealed at the population level,"
COVID-19 poses a serious risk to brain health, even in mild cases, and the effects are now being revealed at the population level,"
·people.com·
COVID Linked to Lower IQ, Poor Memory and Other Negative Impacts on Brain Health
Pioneering discovery and therapeutics at the brain-vascular-immune interface
Pioneering discovery and therapeutics at the brain-vascular-immune interface

A new paper in Cell, “Pioneering discovery and therapeutics at the brain-vascular-immune interface,” describes COVID-19 as a neurological disease alongside multiple sclerosis, Alzheimer’s, stroke and traumatic brain injury.

“COVID-19 can accelerate progression of dementia and induce BBB disruption and inflammatory blood clots causally linked with neuroinflammation and neuronal loss.8 In neurodevelopmental disorders, prematurity and perinatal hypoxia that trigger brain hemorrhage and BBB disruption are risk factors for cerebral palsy, intellectual disability, and autism. Collectively, these risk factors highlight the interconnected vascular and immune triggers of neurological diseases.”

·cell.com·
Pioneering discovery and therapeutics at the brain-vascular-immune interface
COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study
COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study
“COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study”
·nature.com·
COVID-19 related cognitive, structural and functional brain changes among Italian adolescents and young adults: a multimodal longitudinal case-control study
Covid Brain
Covid Brain
“But this week 2 new publications have substantially added to our understanding of the extent that Covid can impair cognitive function across the full gamut— from young, healthy individuals with mild infections to older, hospitalized patients with severe Covid.”
·erictopol.substack.com·
Covid Brain
Long COVID is not the same for everyone: a hierarchical cluster analysis of Long COVID symptoms 9 and 12 months after SARS-CoV-2 test - BMC Infectious Diseases
Long COVID is not the same for everyone: a hierarchical cluster analysis of Long COVID symptoms 9 and 12 months after SARS-CoV-2 test - BMC Infectious Diseases
“Our results suggest that Long COVID is not the same for everyone.”
Our results suggest that Long COVID is not the same for everyone.
·bmcinfectdis.biomedcentral.com·
Long COVID is not the same for everyone: a hierarchical cluster analysis of Long COVID symptoms 9 and 12 months after SARS-CoV-2 test - BMC Infectious Diseases