@keetmuise And we know Covid is causing them…
“I have been experiencing focal seizures since 2021—a year after my first Covid infection. My neurologist told me Covid doesn’t do this & my issues are probably anxiety.”
An Amyloidogenic Fragment of the Spike Protein from SARS-CoV-2 Virus Stimulates the Aggregation and Toxicity of Parkinson’s Disease Protein Alpha-Synuclein
“Overall, our findings raise compelling questions about the potential role of SARS-CoV-2 infection in accelerating or triggering neurodegenerative diseases linked to protein amyloidosis”
A Peripheral Neuron-to-Microglia Signaling Axis Connecting Transient Viral Infection to Persistent Neuroinflammatory States | Research Square
How does a transient viral infection like COVID lead to long lasting neurologic symptoms?
In humans and in animal models, SARS-CoV-2 can damage peripheral sensory nerves in the nose, leaving behind debris that can then trigger inflammation in brain microglia for weeks to months after infection, which can then lead to post-viral neurological symptoms like cognitive dysfunction (brain fog).
The peripheral neuron-to-microglia axis offers a potential explanation for persistent inflammation seen in conditions like Long COVID and ME/CFS.
Scientists Find Shocking Link Between COVID and Alzheimer's — Best Life
My note: THERE IS NOTHING SHOCKING ABOUT THIS. LOOK AT THE STUDIES GOING BACK TO 2020!!!
Abstract WP400: SARS-CoV-2 Spike Protein Accelerates Alzheimer’s Disease-Related Dementia Through Increased Cerebrovascular Inflammation in hACE2 Mice | Stroke
Normal pressure hydrocephalus associated with COVID-19 infection: a case report - BMC Infectious Diseases
Hydrocephalus secondary to COVID-19 infection | QJM: An International Journal of Medicine | Oxford Academic
Investigating the Neuroimmune, Cerebrovascular, and Cognitive Disturbances Associated with SARS‑CoV‑2 Infection: A Systematic Review of Post‑Acute Outcomes | Research Square
“A systematic review of 73,435 COVID-19 survivors found that 42% had persistent neuroinflammation, 22% had cerebrovascular injury, and 58% had cognitive impairment.”
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Exploring the Persistence of the Spike Protein along the Skull-Meninges-Brain Axis and the Neurological Effects of COVID-19
This analysis is supported by numerous videos and illustrations.
Cerebrospinal Fluid Offers Clues to Post-COVID ‘Brain Fog’ | UC San Francisco
“Over-Stimulated Immune System May Be Impetus to Cognitive Symptoms, UCSF-Led Study Shows”
Neurological complications after COVID-19: A narrative review
Neuroimmune Dysfunction Facilitates COVID-19-Associated Neurological C
A review of the neurological manifestations of SARS-CoV-2 infection and long-term effects
Persistence of spike protein at the skull-meninges-brain axis may contribute to the neurological sequelae of COVID-19
Evidence that a COVID-19 infection can induce neurological sequelae.
The SARSCoV2 spike protein can persist in the brain—skull bone marrow and meninges—to induce neurologic damage
SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it.
In mice, it caused inflammation, anxiety, and worsened brain injuries. Vaccines reduced but did not fully eliminate it.
SARS-CoV-2 spike protein persists in the skull-meninges-brain axis in COVID-19 patients•Spike protein is sufficient to induce brain pathological and behavioral changes in mice•Spike protein enhances brain vulnerability and exacerbates neurological damage in mice•mRNA vaccines reduce, but do not eliminate, the spike burden
Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron Subvariants—Single-Center Study
“The Omicron variant of SARS-CoV-2 presents a wide spectrum of neurological manifestations."
"Although there is an improvement in the survival rate of patients with COVID-19, the frequency of neurological manifestations increases."
"The occurrence of delirium, cerebrovascular diseases, and ischemic stroke results in higher mortality."
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
“We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease”
We identified dysregulation of mitochondrial and synaptic pathways in deep-layer excitatory neurons and upregulation of neuroinflammation in glia, consistent across both mRNA and protein. Remarkably, these alterations overlapped substantially with changes in age-related neurodegenerative diseases, including Parkinson’s disease and Alzheimer’s disease
Neurological complications caused by SARS-CoV-2
Very comprehensive evaluation of known neurological damage from SarsCov2:
“The pathogenesis of neurological disorders caused by SARS-CoV-2 involves several mechanisms. First, SARS-CoV-2 could enter the brain through retrograde transmission & hematogenous routes & disrupt brain function & structure, thus causing or exacerbating neurological disorders…”