Clinical and CSF single-cell profiling of post-COVID-19 cognitive impairment
we found that cognitive dysfunction is common; is not influenced by mood, fatigue, or sleepiness; and is correlated with MRI changes in very few people. In a subgroup that
Thread by @JamesThrot on Thread Reader App
“Let’s talk about COVID, brain damage & society.
Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?
This thread is for the skeptics.
I’m a neurologist, stay with me 🧵”
Let’s talk about COVID, brain damage & society.
Specifically, what happens when a neurotropic virus repeatedly infects the population, targeting the frontal lobe & almost nobody talks about the consequences?
This thread is for the skeptics.
I’m a neurologist, stay with me 🧵
Human challenge study reveals lasting cognitive decline after mild COVID-19
“significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.”
Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed
Functional brain abnormalities in post COVID-19 condition and their relationship with cognition
Harry Spoelstra (@HarrySpoelstra) on X
Long-term neurological and cognitive impact of COVID-19: a systematic review and meta-analysis in over 4 million patients
The Molecular Mechanisms of Cognitive Dysfunction in Long COVID: A Narrative Review
The molecular mechanisms of cognitive dysfunction in Long COVID: A Narrative Review
Self-reported health, neuropsychological tests and biomarkers in fully recovered COVID-19 patients vs patients with post-COVID cognitive symptoms: A pilot study | PLOS One
Cross-Section of Neurological Manifestations Among SARS-CoV-2 Omicron Subvariants—Single-Center Study
“The Omicron variant of SARS-CoV-2 presents a wide spectrum of neurological manifestations."
"Although there is an improvement in the survival rate of patients with COVID-19, the frequency of neurological manifestations increases."
"The occurrence of delirium, cerebrovascular diseases, and ischemic stroke results in higher mortality."
Cognitive profile following COVID-19 infection: Clinical predictors leading to neuropsychological impairment
Covid itself causes cognitive impairment. From 2020, prior to Covid vaccination of any kind:
“In our cohort of COVID-19 patients neurologic manifestations were frequent, including cognitive impairment.”
Driving Under the Cognitive Influence of COVID-19: Exploring the Impact of Acute SARS-CoV-2 Infection on Road Safety | Neurology
"The study suggests that acute COVID-19, regardless of Long COVID status, is linked to an increased risk of car crashes presumably due to neurologic changes caused by SARS-CoV-2."
Long COVID is not the same for everyone: a hierarchical cluster analysis of Long COVID symptoms 9 and 12 months after SARS-CoV-2 test - BMC Infectious Diseases
“Our results suggest that Long COVID is not the same for everyone.”
Our results suggest that Long COVID is not the same for everyone.