Search Covid and Brain Damage

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Study: COVID-19 Can Accelerate Brain Aging, Lead to Irreversible Neurological Conditions

“Tiny leakages of blood in crucial brain regions of patients infected with Covid-19 can accelerate brain aging and lead to irreversible neurodegenerative conditions, according to a Houston Methodist review study.”

#Brain #brain bleed #cognition #vascular

·houstonmethodist.org·Jun 13, 2023

Study: COVID-19 Can Accelerate Brain Aging, Lead to Irreversible Neurological Conditions

Cerebral hypoperfusion in post-COVID-19 cognitively impaired subjects revealed by arterial spin labeling MRI

New paper comparing #LongCovid patients to matched controls found significantly reduced blood flow all over the brain - frontal, temporal, & parietal lobes.

Middle column in the picture below are healthy controls; red/warm colors = more blood flow. 1/

#Brain #vascular

·nature.com·Jun 13, 2023

Cerebral hypoperfusion in post-COVID-19 cognitively impaired subjects revealed by arterial spin labeling MRI

Study examining patients at a long COVID neurology clinic showing deficits in executive, attention, language and memory functions. MRIs showed reduced blood flow to frontal, parietal and temporal regions of the brain compared to age & sex matched controls

#Brain #executive function #Memory #cognition #language #vascular

·nature.com·Jun 13, 2023

Cerebral hypoperfusion in post-COVID-19 cognitively impaired subjects revealed by arterial spin labeling MRI

COVID Is Doing Something to Our Sleep, And Even to Our Dreams

"COVID can have a direct impact on the brain, including the areas that control both wake and sleep states...possible mechanisms could include the virus infecting the central nervous system or affecting the brain's blood supply."

#Brain #sleep #vascular

·sciencealert.com·Jun 13, 2023

COVID Is Doing Something to Our Sleep, And Even to Our Dreams

Neurovascular Injury Evident in Sudden Death of Patients With COVID-19

"Neurovascular injury during COVID-19 infection is likely triggered by antibody-mediated cytotoxicity directed at endothelial cells."

#Brain #Endothelium #vascular #Immune system

·neurologyadvisor.com·Jun 13, 2023

Neurovascular Injury Evident in Sudden Death of Patients With COVID-19

Small NIH study reveals how immune response triggered by COVID-19 may

"scientists found evidence that antibodies—proteins produced by the immune system in response to viruses and other invaders--are involved in an attack on the cells lining the brain’s blood vessels..." Cross-referenced in thread on Covid & immune system

#Brain #Immune system #vascular

·nih.gov·Jun 13, 2023

Small NIH study reveals how immune response triggered by COVID-19 may

Neurovascular injury with complement activation and inflammation in COVID-19

The microvascular injury and inflammation of the brain, with immune complex formation, that can occur from Covid, from in-depth assessment of 9 patient autopsies and controls.

#Brain #vascular #Neuroinflammation #Immune system

·academic.oup.com·Jun 13, 2023

Neurovascular injury with complement activation and inflammation in COVID-19

COVID Brain Problems May Stem From Attack on Endothelial Cells

"COVID Brain Problems May Stem From Attack on Endothelial Cells — Findings could have implications for treating long COVID"

#Brain #Endothelium #vascular #Long Covid

·medpagetoday.com·Jun 13, 2023

COVID Brain Problems May Stem From Attack on Endothelial Cells

Neurovascular injury with complement activation and inflammation in COVID-19

"All patients had multifocal vascular damage as determined by leakage of serum proteins into the brain parenchyma. This was accompanied by widespread endothelial cell activation...microthrombi were found adherent to the endothelial cells..."

#Brain #vascular #Clots

·academic.oup.com·Jun 13, 2023

Neurovascular injury with complement activation and inflammation in COVID-19

Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings

"investigate adults at least four months after recovering from mild COVID-19...In approximately 1/4 of mild-COVID-19 individuals, we detected a specific visuoconstructive deficit, which was associated with changes in molecular and structural brain imaging"

#Brain #Brain shrinkage #vascular

·nature.com·Jun 13, 2023

Selective visuoconstructional impairment following mild COVID-19 with inflammatory and neuroimaging correlation findings

Coronavirus effects linger in once-healthy brains. Long COVID's toll feared in Louisiana.

“‘My great concern is that there could be a wave of dementia cases over the next 5 to 10 years that can be directly traced back to this pandemic…It is a vascular virus…It does bad things to blood vessels in our bodies.’”

#Brain #vascular #dementia

·nola.com·Jun 13, 2023

Coronavirus effects linger in once-healthy brains. Long COVID's toll feared in Louisiana.