Low Cortisol Levels May Be Key to Long COVID Symptoms
Yet another stretch for one size fits all explanation of a multifaceted condition. Still, important finding:
“A groundbreaking study from the University of Colorado Boulder has uncovered a potential mechanism behind the persistent neurological symptoms experienced by many Long COVID sufferers. The research, published in Brain, Behavior, and Immunity, points to a significant drop in cortisol levels in the brain as a possible culprit, offering new insights into this complex and widespread condition.”
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
EXTREME and incomplete oversimplification of the many complex neurological issues caused by SarsCov2, but important facet of the vaguely defined “brain fog” of Long Covid and post-acute Covid lingering symptoms.
“Neurological symptoms have been widely observed in COVID-19 patients, with many survivors exhibiting persistent neurological and cognitive impairment. New research from the University of Minnesota found that COVID-19 triggers inflammation in the brain, which is linked to many COVID-related symptoms such as fatigue and ‘brain fog.’”
Internal tremors and vibrations in long COVID: a cross-sectional study
"Most people associate symptoms such as shaking or trembling movements with neuromuscular diseases, such as Parkinson’s disease—but now, some Long COVID patients have reported experiencing internal tremors and vibrations."
Northwestern Medicine study shows neurologic symptoms of long COVID differ based on severity of initial COVID-19 infection - West Chicago Voice : Local News West Chicago News
Long Covid brain fog occurs in approximately a third of #COVID-19 survivors and is now the THIRD leading neurologic disorder in the United States. - Dr. Igor Koralnik Northwestern Medicine study details neurologic symptoms.
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
“This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, all the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...”
The most helpful educational series out there right now is Dr. Jarred Youngers video series on "Neuroinflammation, Pain, and Fatigue".
“The most helpful #MECFS #LongCovid educational series out there right now is Dr. Jarred Youngers video series on "Neuroinflammation, Pain, and Fatigue".
Start at the beginning or jump in as your interest is piqued. There are now 28 shortish videos (most under 15min) and this series will provide an incredible grounding in all things neuroinflammation.
Dr. Younger is all about the 'tools' and 'interventions' and patient education and has done more to educate us about available interventions for neuroinflammation than any other researcher.”
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
University of Colorado study in rats demonstrates that SARS-CoV-2 protein activity drives longer-term vulnerability to another infection, augmenting physiological problems such as neuroinflammation, autonomic dysregulation, and hormonal imbalances
University of Colorado study in rats demonstrates that SARS-CoV-2 protein activity drives longer-term vulnerability to another infection, augmenting physiological problems such as neuroinflammation, autonomic dysregulation, and hormonal imbalances
Wes Wilson on Twitter
Study from CAMH found, via PET scans, elevated levels of the protein TSPO, a brain marker of inflammation, in patients with onset of depression in long covid
more than 200 million globally may experience lingering neurological symptoms from COVID, including depression, memory impairment, slower motor control, low motivation and energy, for months to even years due to brain inflammation from long COVID
this along side everything we have learned in the last 2.5 years ( much summarized in the lit review done by Stanford and Yale, linked in the comments ) moves us a step closer in understanding the underlying biological mechanisms behind these symptoms
Nate Bear on Twitter
Thread on Twitter: New study documents the case of two previously healthy sisters - 11 and 13-years-old - with new-onset cognitive decline after mild covid. The ability of their brains to consume glucose had been impaired - an initiating factor for dementia, Parkinson's and Alzheimer's disease 🧵
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
154,000 veterans who had COVID were 1.4 times likelier to have a neurologic condition--memory problems, stroke, neuropathy, mental health disorders, migraines, or seizures--in year following illness. This was true for all COVID cases, from mild to severe.
UCSD Scientists Find COVID Damages Brain Cell Synapses, But Propose Treatment
“an FDA-approved antiviral drug might be repurposed to restore infected brain cells to health.. sofosbuvir — already an approved treatment for hepatitis C – – effectively inhibited SARS-CoV-2 replication and reversed damages in infected brain organoids.”
Canadian neurocognitive disorder expert speaks to Global Workers Inquest into the Pandemic: “To say ‘they are old, they can die’—it’s criminal”
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
The Risks of Even Mild COVID-19: 1 in 4 Showing Cognitive Deficits After Mild Case, Brazilian Study Finds
"new research suggests even a mild SARS-CoV-2 infection could lead to persistent and even long-term consequences, some that may not be known for years or even decades... 'under-studied' groups: those with mild-COVID-19 and children."
The effects of COVID-19 on cognitive performance in a community-based cohort: A COVID Symptom Study Biobank observational study
"Cognitive deficits following SARS-CoV-2 infection were detectable nearly two years post infection, and largest for individuals with longer symptom durations, ongoing symptoms, and/or more severe infection."
