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Low Cortisol Levels May Be Key to Long COVID Symptoms
Low Cortisol Levels May Be Key to Long COVID Symptoms

Yet another stretch for one size fits all explanation of a multifaceted condition. Still, important finding:

“A groundbreaking study from the University of Colorado Boulder has uncovered a potential mechanism behind the persistent neurological symptoms experienced by many Long COVID sufferers. The research, published in Brain, Behavior, and Immunity, points to a significant drop in cortisol levels in the brain as a possible culprit, offering new insights into this complex and widespread condition.”

·scienceblog.com·
Low Cortisol Levels May Be Key to Long COVID Symptoms
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota

EXTREME and incomplete oversimplification of the many complex neurological issues caused by SarsCov2, but important facet of the vaguely defined “brain fog” of Long Covid and post-acute Covid lingering symptoms.

“Neurological symptoms have been widely observed in COVID-19 patients, with many survivors exhibiting persistent neurological and cognitive impairment. New research from the University of Minnesota found that COVID-19 triggers inflammation in the brain, which is linked to many COVID-related symptoms such as fatigue and ‘brain fog.’”

·twin-cities.umn.edu·
Study uncovers the basis of COVID-19-related brain fog | University of Minnesota
Northwestern Medicine study shows neurologic symptoms of long COVID differ based on severity of initial COVID-19 infection - West Chicago Voice : Local News West Chicago News
Northwestern Medicine study shows neurologic symptoms of long COVID differ based on severity of initial COVID-19 infection - West Chicago Voice : Local News West Chicago News

Long Covid brain fog occurs in approximately a third of #COVID-19 survivors and is now the THIRD leading neurologic disorder in the United States. - Dr. Igor Koralnik Northwestern Medicine study details neurologic symptoms.

·westchicagovoice.com·
Northwestern Medicine study shows neurologic symptoms of long COVID differ based on severity of initial COVID-19 infection - West Chicago Voice : Local News West Chicago News
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
“This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, all the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...”
·x.com·
make sure that it hasn't returned. This year, my Dr. told me that they have found that if people who survived brain tumors get Covid, *all* the symptoms of their brain tumor will return. It has something to do with the hole in your brain that remains...
The most helpful educational series out there right now is Dr. Jarred Youngers video series on "Neuroinflammation, Pain, and Fatigue".
The most helpful educational series out there right now is Dr. Jarred Youngers video series on "Neuroinflammation, Pain, and Fatigue".

“The most helpful #MECFS #LongCovid educational series out there right now is Dr. Jarred Youngers video series on "Neuroinflammation, Pain, and Fatigue".

Start at the beginning or jump in as your interest is piqued. There are now 28 shortish videos (most under 15min) and this series will provide an incredible grounding in all things neuroinflammation.

Dr. Younger is all about the 'tools' and 'interventions' and patient education and has done more to educate us about available interventions for neuroinflammation than any other researcher.”

·x.com·
The most helpful educational series out there right now is Dr. Jarred Youngers video series on "Neuroinflammation, Pain, and Fatigue".
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
University of Colorado study in rats demonstrates that SARS-CoV-2 protein activity drives longer-term vulnerability to another infection, augmenting physiological problems such as neuroinflammation, autonomic dysregulation, and hormonal imbalances
University of Colorado study in rats demonstrates that SARS-CoV-2 protein activity drives longer-term vulnerability to another infection, augmenting physiological problems such as neuroinflammation, autonomic dysregulation, and hormonal imbalances
·polybio.org·
“Multiple hit” model shows that COVID protein potentiates subsequent infection-related neuroinflammation and other physiological problems - PolyBio Research Foundation
Wes Wilson on Twitter
Wes Wilson on Twitter

Study from CAMH found, via PET scans, elevated levels of the protein TSPO, a brain marker of inflammation, in patients with onset of depression in long covid

more than 200 million globally may experience lingering neurological symptoms from COVID, including depression, memory impairment, slower motor control, low motivation and energy, for months to even years due to brain inflammation from long COVID

this along side everything we have learned in the last 2.5 years ( much summarized in the lit review done by Stanford and Yale, linked in the comments ) moves us a step closer in understanding the underlying biological mechanisms behind these symptoms

·twitter.com·
Wes Wilson on Twitter
laurie allee on Twitter
laurie allee on Twitter
"This comprehensive analysis of patients with neuro-PASC revealed a disabling but difficult to characterize syndrome that develops even after relatively mild COVID-19. A common feature is memory impairment."
·twitter.com·
laurie allee on Twitter
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
154,000 veterans who had COVID were 1.4 times likelier to have a neurologic condition--memory problems, stroke, neuropathy, mental health disorders, migraines, or seizures--in year following illness. This was true for all COVID cases, from mild to severe.
·alzforum.org·
Long COVID and Dementia: The Link Is Still Elusive | ALZFORUM
Could long covid change brain activity
Could long covid change brain activity
"Scientists report that brain scans of long COVID patients show abnormal activity in areas related to memory...likened the brain changes to what happens in HIV patients and in those with traumatic brain injury."
·usnews.com·
Could long covid change brain activity
Canadian neurocognitive disorder expert speaks to Global Workers Inquest into the Pandemic: “To say ‘they are old, they can die’—it’s criminal”
Canadian neurocognitive disorder expert speaks to Global Workers Inquest into the Pandemic: “To say ‘they are old, they can die’—it’s criminal”
"The impact I am seeing on my clients post-COVID is something I hadn’t seen previously in the years I have worked in this field. The cognitive decline post-COVID infection is immense, thus confirming the impact this virus has on the brain..."
·wsws.org·
Canadian neurocognitive disorder expert speaks to Global Workers Inquest into the Pandemic: “To say ‘they are old, they can die’—it’s criminal”
The effects of COVID-19 on cognitive performance in a community-based cohort: A COVID Symptom Study Biobank observational study
The effects of COVID-19 on cognitive performance in a community-based cohort: A COVID Symptom Study Biobank observational study
"Cognitive deficits following SARS-CoV-2 infection were detectable nearly two years post infection, and largest for individuals with longer symptom durations, ongoing symptoms, and/or more severe infection."
·medrxiv.org·
The effects of COVID-19 on cognitive performance in a community-based cohort: A COVID Symptom Study Biobank observational study
BIRCH on Twitter
BIRCH on Twitter

Even mild Covid can cause impairments with all five of your senses for long periods after the initial infection. *all images available as editable, printable files, DM for info.

·twitter.com·
BIRCH on Twitter