Just published @Nature How fibrin drives brain inflammation in acute and #LongCovid and that a monoclonal antibody to fibrin protects against microglial activation
Not a cold.
A mutation in the Spike Protein of SARS-CoV-2 could help it infect brain cells using a secret “back door” after entering the central nervous system.
SARS2 can invade your brain.
All variants are neuroinvasive.
Neuroinvasion and anosmia are independent phenomena upon infection.
SARS2 can travel retrogradely and anterogradely along axons in neuron-epithelial networks.
Neuroscience News: 'COVID’s Spike Protein Enhances Ability to Infect Brain'
'The new collaborative study between scientists at Northwestern University & the Univ. of Illinois-Chicago uncovered a series of mutations in the SARS-CoV-2 spike protein..'
“new study has added fuel to concerns that America could face a surge in dementias in coming years & decades due to COVID.”
“Changes in blood flow could cause frequent, small injuries to brain tissue, depriving oxygen often enough to cause.. dementia.”
Forbes: 'InnovationRx: COVID May Be Causing Mental Illness—And Rewiring Our Brains'
New findings in JAMA Psychiatry find that levels of mental illness such as depression, anxiety and self-harm are elevated after a COVID-19 diagnosis
“‘…there is evidence of fragments or an inflammatory kind of a massive inflammatory response that occurs triggered by COVID. And those inflammatory markers we tend to notice in the brain.’
And that could cause something called COVID-19 Cognitive Impairment.
‘And we are going to compare people with COVID cognitive impairment. To be clear on this, I think that COVID can cause cognitive impairment and maybe even dementia…’”
Yet another stretch for one size fits all explanation of a multifaceted condition. Still, important finding:
“A groundbreaking study from the University of Colorado Boulder has uncovered a potential mechanism behind the persistent neurological symptoms experienced by many Long COVID sufferers. The research, published in Brain, Behavior, and Immunity, points to a significant drop in cortisol levels in the brain as a possible culprit, offering new insights into this complex and widespread condition.”
EXTREME and incomplete oversimplification of the many complex neurological issues caused by SarsCov2, but important facet of the vaguely defined “brain fog” of Long Covid and post-acute Covid lingering symptoms.
“Neurological symptoms have been widely observed in COVID-19 patients, with many survivors exhibiting persistent neurological and cognitive impairment. New research from the University of Minnesota found that COVID-19 triggers inflammation in the brain, which is linked to many COVID-related symptoms such as fatigue and ‘brain fog.’”
“Want to see what a “COVID Brain” can look like?
Here’s mine. The white spots are not supposed to be there. You can’t see the microhemorrhages or swelling.
Infected early March ‘20- pre-vaccine.But the threat is still here for everyone-vax or not, young or old.
Please mask up.”
In addition to brain fog, COVID-19 can lead to an array of problems, including headaches, seizure disorders, strokes, sleep problems, and tingling and paralysis of the nerves, as well as several mental health disorders. A large and growing body of evidence amassed throughout the pandemic details the many ways that COVID-19 leaves an indelible mark on the brain. But the specific pathways by which the virus does so are still being elucidated, and curative treatments are nonexistent.