COVID-19 May Promote Tumor Development in Patients With Cancer
or patients with existing cancer, Covid infections may promote tumor development.
Laura Miers on Twitter
“EBV is found in the bone marrow of 90% of people, CMV in 60% of people and herpes simplex in 50% of individuals in the dormant state. Herpes and CMV are found in various body parts.”
This seems important.
COVID-19: a potential driver of immune-mediated breast cancer recurrence? - Breast Cancer Research
COVID-19: a potential driver of immune-mediated breast cancer recurrence?
Tom Andrews on Twitter
SARS-COV-2 causes immunopathology: the effects of COVID upon T-cells & other parts of immune system mean direct & indirect harm, lower protection against other infectious & non infectious diseases (recurrence of chronic infections, control of new cancer, recurrence of old cancer)
Anthony J Leonardi, MBBS, PhD on Twitter
T cells die and get depleted
If you dysregulate this you can get things like lymphoproliferation or cancers with too little death, and depletion with too much
Don't annoy me with people in denial about T cell death signatures
The findings are robust in Covid-19
Laura Miers on Twitter
What if Covid leads to cancer later? What will we do when we already infected everyone?
Perhaps that’s why mass infection with a novel virus isn’t advisable. Some countries understand this aspect, and some countries don’t.
Kashyap Patel, MD, Sees Link Between COVID-19 and Cancer Progression, Calls for More Biomarker Testing
“With COVID-19 added to the mix, Patel now fears a ‘perfect storm’ of factors will trigger inflammatory responses in some patients, causing cancer to arrive years earlier than normal and making it deadlier once it is diagnosed.”
COVID-19 can lead to rapid progression of cervical intraepithelial neoplasia by dysregulating the immune system: A hypothesis
COVID-19 can lead to rapid progression of cervical intraepithelial neoplasia by dysregulating the immune system: A hypothesis Author links open overlay panel
Anthony J Leonardi, MBBS, PhD on Twitter
I can’t believe what I’m seeing
T cell dysregulation and exhaustion from Covid may have caused rapid progression of HPV related cancer
Echoing my hypothesis from three years ago
David CisMan on Twitter
p53 is also called “tumor suppressor gene”. Mutations in p53 are responsible for some family cancer syndromes.
If sars-cov-2 disrupts p53, we may be at the beginning of a very wild ride. Quote Tweet Mark Ungrin @mark_ung
p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics)
Related: p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics)
Cancer as a prospective sequela of long COVID-19 - PubMed
Cancer as a prospective sequela of long COVID-19