Is SARS-CoV-2 an oncogenic virus?
Way back in Nov 2022 the impacts of Covid infection on turning off your tumour suppressor were highlighted
‘Unusual’ cancers emerged after the pandemic. Doctors ask if covid is to blame.
P0304 SARS-COV-2 in Colorectal Cancer of IBD Patients | Journal of Crohn's and Colitis | Oxford Academic
6 patients with inflammatory bowel disease were infected with SARSCoV2, then diagnosed with anorectal cancer.
Detection of the SarsCov2 protein in ALL tumors raises questions about its role in the development of colorectal cancer.
SARS-COV-2 in Colorectal Cancer of IBD Patients.
“has been hypothesized that inflammation related to SARS-CoV-2 infection can affect cancer cell proliferation, without having a direct oncogenic effect.
➡️IBD-associated CRC (colorectal cancer) arises from a specific carcinogenic pathway involving chronic inflammation which is distinct from the traditional pathways.”
SARS-CoV-2 infection as a potential risk factor for the development of cancer
““…all patients should be regularly screened for cancer after SARS-CoV-2 infection, as the virus has been shown not only to affect cancer progression but also to induce oncogenesis and cancer recurrence.”
With a depleted immune system, my oncologist said long Covid either caused or exacerbated my stage IV cancer, and 20% of cancers are viral-based.
“With a depleted immune system, my oncologist said long Covid either caused or exacerbated my stage IV cancer, and 20% of cancers are viral-based.”
We have so many oncology patients who were either in remission or improving & then after one or more covid infections their cancer came back or worsened. I dread the thought of another infection while I'm fighting bladder cancer. I 💯 believe SARS-CoV-2 can be oncogenic.
“We have so many oncology patients who were either in remission or improving & then after one or more covid infections their cancer came back or worsened. I dread the thought of another infection while I'm fighting bladder cancer. I 💯 believe SARS-CoV-2 can be oncogenic.”
‘Unusual’ cancers emerged after the pandemic. Doctors ask if covid is to blame.
“..:Patel and other concerned scientists are calling on the U.S. government to make this question [of whether Covid is causing rise in cancer] a priority knowing it could affect treatment and management of millions of cancer patients for decades to come.”
Via WaPo: “I’ve been in practice 23 years and have never seen anything like this,” oncologist Kashyap Patel said.
“‘I’ve been in practice 23 years and have never seen anything like this,’ oncologist Kashyap Patel said.
Asutosh Gor, another oncologist, agreed: ‘We were all shaken.’
There was other weirdness, too: multiple patients contending w multiple types of cancer arising almost simultaneously, and more than a dozen new cases of other rare cancers…. The uptick in aggressive, late-stage cancers since the…pandemic is confirmed by early national data and a number of large cancer institutions.
Many…dismissed the trend as a consequence of disruptions to health care that began in 2020.
But not everyone.
The idea that some viruses can cause or accelerate cancer is hardly new… 15 to 20 percent of all cancers worldwide originate from infectious agents…”
In vitro analysis suggests that SARS-CoV-2 infection differentially modulates cancer-like phenotypes and cytokine expression in colorectal and prostate cancer cells
“Our results suggest that SARS-CoV-2 infection does influence various cancer cellular phenotypes and expression of molecular cancer markers and proinflammatory cytokines, albeit in a cell-type-specific manner. Our findings hint at the need for further studies and could have implications for evaluating the impact of other viruses on cancer progression.”
Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?
“An in-silico study predicted that pancreatic adenocarcinoma was the most likely cancer to occur following infection with SARS-CoV-2.”