“Quick 🧵on the current state of Iota-carrageenan nasal sprays: Efficacy, safety, Betadine shortages, buying options for US & Can. markets.
I-C sprays are the only option on the market that have a real-world randomized, double-blind, placebo-controlled study backing them up. 1/14”
“Current nasal sprays offer limited protection against respiratory pathogens because they have a single mechanism of protection. They either neutralize pathogens or block their entry into the cells lining the nose, and they perform both tasks with limited efficacy.
‘We developed a drug-free formulation to block germs in three ways — the spray forms a gel-like matrix that enhances the capture of respiratory droplets, immobilizes the germs blocking their transport into the nasal lining, and effectively neutralizes them, preventing infection,’”
Nose Sprays: A Last Line of Defense in a World Hellbent on Giving You Covid Here's what we know.
“Preclinical studies suggest a drug-free nasal spray could ward off respiratory infections Researchers from the Brigham detail how the spray they created may offer broad-spectrum protection from respiratory infections by COVID-19, influenza, everyday cold viruses, and pneumonia-causing bacteria”
New, promising data on Profi Nasal Spray (aka PCANS) as prophylaxis for respiratory viruses:
“The researchers developed the formulation and studied its ability to capture respiratory droplets in a 3D-printed replica of a human nose. They showed that when sprayed in the nasal cavity replica, PCANS captured twice as many droplets as mucus alone.
