@laurieallee thanks for highlighting my paper niclosamide, I’ll be happy to discuss with you and or anybody else who is interested in advancing this potentially preventative nasal spray and early treatment throat spray into testing
Related: "NCL has anti-inflammatory and immune regulatory effects by modulating the release of pro-inflammatory cytokines...anti-SARS-CoV-2 effect via interruption of viral life-cycle and/or induction of cytopathic effect."
April, 2023:
"These results show a potentially more rapid route to FDA approval, bringing a new commercial opportunity that could make the nasal sprays more readily available...not just potentially for COVID-19, but also for all respiratory viruses"
"Simple pH adjustment may enable a preventative Covid-19 nasal and throat spray
Higher pH makes a common metabolic inhibitor medication practical for nose and throat spray applications against COVID-19"
From 2020: "Inhaled Niclosamide a Potential Effective Antiviral to Treat COVID-19"
Starting thread on niclosamide:
"These researchers developed a prophylactic nasal spray and early treatment throat spray by repurposing niclosamide, a metabolic inhibitor previously used for 60 years for gut parasite infections." https://dukechronicle.com/article/2022/03/duke-university-scientist-coronavirus-covid-treatment-nasal-spray#:~:text=Niclosamide%20works%20by%20blocking%20three%20of%20the%20six,said.%20Formerly%2C%20niclosamide%20was%20FDA-approved%20in%20pill%20form.