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A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
"A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19"
·thelancet.com·
A randomized, double-blind, placebo-controlled phase 1 trial of inhaled and intranasal niclosamide: A broad spectrum antiviral candidate for treatment of COVID-19
laurie allee on Twitter
laurie allee on Twitter

Starting thread on niclosamide:

"These researchers developed a prophylactic nasal spray and early treatment throat spray by repurposing niclosamide, a metabolic inhibitor previously used for 60 years for gut parasite infections." https://dukechronicle.com/article/2022/03/duke-university-scientist-coronavirus-covid-treatment-nasal-spray#:~:text=Niclosamide%20works%20by%20blocking%20three%20of%20the%20six,said.%20Formerly%2C%20niclosamide%20was%20FDA-approved%20in%20pill%20form.

·twitter.com·
laurie allee on Twitter
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections - PubMed
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections - PubMed
"prophylactic-nasal and early-treatment throat-sprays could help prevent infection and reduce viral load. Niclosamide has the potential to treat a broad-range of viral infections...as mucin-penetrating solutions that can reach underlying epithelial cells."
·pubmed.ncbi.nlm.nih.gov·
The pH Dependence of Niclosamide Solubility, Dissolution, and Morphology: Motivation for Potentially Universal Mucin-Penetrating Nasal and Throat Sprays for COVID19, its Variants and other Viral Infections - PubMed