How COVID-19 Can Attack the Inner Ear
"Researchers noted that they observed SARS-Cov-2 infection of OPCs, a cell type present in the developing fetal inner ear."
Covid and Pregnancy
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COVID caused brain damage in 2 infants infected during pregnancy -US study
“Researchers at the University of Miami reported on Thursday what they believe are the first two confirmed cases in which the SARS-CoV-2 virus crossed a mother's placenta & caused brain damage in the infants they were carrying.”
COVID in Pregnancy May Affect Boys' Neurodevelopment: Study
"Boys born to mothers infected with SARS‐CoV‐2 during pregnancy may be more likely to receive a diagnosis of a neurodevelopmental disorder by age 12 months, according to new research."
Covid Worsened a Health Crisis Among Pregnant Women
“Pregnant women with Covid face a sevenfold risk of dying compared with uninfected pregnant women…. The infection also makes it more likely that a woman will give birth prematurely and that the baby will require neonatal intensive care”
COVID-19 Infection May Induce Fetal Brain Hemorrhages, Scientists Warn
"COVID-19 Infection May Induce Fetal Brain Hemorrhages, Scientists Warn"
Neurodevelopmental Outcomes at 1 Year in Infants Following SARS-CoV-2 Exposure in Utero
"those born to the 222 mothers with a positive SARS-CoV-2 polymerase chain reaction test during pregnancy were more likely to receive a neurodevelopmental diagnosis in the first 12 months after delivery,"
Chris Turnbull on Twitter
Detailed analysis thread with commentary Sars2/Covid:new study shows that the fetuses of those infected with virus have significant 'organ abnormalities' including brain lesions and liver 'alterations'
-Fetuses also found to have significantly restricted growth
-Virus infects placenta directly
TACT on Twitter
Detailed analysis thread on Twitter Volume 43, Issue 5, September–October 2022
All newborns whose mothers had COVID during pregnancy should be evaluated for hearing loss, according to this study. "The Hearing Loss in newborns caused by maternal SARS-CoV-2 infection is still not fully understood. Therefore, prospective, large-scale clinical studies need to be conducted in the future."
Anne V Herdman Royal, MD (she/her) on Twitter
Detailed analysis thread This is absolutely catastrophic placental failure from a condition called SARS-CoV-2-related histiocytic intervillositis. In other words, #CovidPlacenta 😔 1/ #GetVaccinatedInPregnancy #PathTwitter
Janic Feth on Twitter
Anecdote This is what I’ve been saying. We are tracking multiple poor outcomes at work in our referrals to Infant Development for babies born to mothers who had COVID during pregnancy. Our biggest concerns stem from infection after 20 weeks gestation. This includes increased admissions to NICU immediately after birth, but also increased global developmental delays. It absolutely stands to reason that they are also then at increased risk for more severe outcomes when sick.
Effects of SARS-CoV-2 on prenatal lung growth assessed by fetal MRI
Effects of SARS-CoV-2 on prenatal lung growth assessed by fetal MRI
Covid pregnancy preeclampsia stillbirths
"Researchers are studying spikes in maternal complications among those with the coronavirus."
COVID-19 infection increases risk for preeclampsia, study finds
"researchers said their systematic review shows that women with SARS-CoV-2 infection during pregnancy had 62% higher odds of developing preeclampsia than those without the infection during pregnancy."
Covid-19 And Preeclampsia
"INTERCOVID study... pregnant individuals with COVID-19 had almost two-fold higher risk of preeclampsia, as well as other adverse outcomes including maternal mortality, severe infection, and preterm birth compared to pregnant individuals without COVID-19."
Doctors Investigate Several Stillbirths Among Moms with COVID-19
"After a handful of cases in Ireland, clinicians there are warning that the virus might infect the placenta in very rare instances and cause fetal distress"
COVID-19 during pregnancy damages the placenta's immune response to further infections
COVID-19 during pregnancy damages the placenta's immune response to further infections
Preeclampsia almost doubled for women who had COVID-19 while pregnant, new study shows
Preeclampsia almost doubled for women who had COVID-19 while pregnant, new study shows
Possible COVID-19 Maternal-to-Neonate Vertical Transmission in a Case of Early Neonatal Infection
Possible COVID-19 Maternal-to-Neonate Vertical Transmission in a Case of Early Neonatal Infection
SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy
SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy "Despite negative SARS CoV-2 nasal PCRs from all newborns, viral RNAs and Spike protein were detected in the stool of 11 out of 14 newborns as early as the first day of life and increased over time in 6."
Neurodevelopmental Outcomes at 1 Year in Infants Following SARS-CoV-2 Exposure in Utero
Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy
Roland Baker on Twitter
Detailed analysis JAMA: Neurodevelopmental Outcomes at 1 Year in Infants of Mothers Who Tested Positive for SARS-CoV-2 During Pregnancy: were more likely to receive a neurodevelopmental diagnosis in the first 12 months after delivery even accounting for preterm delivery.
Mrs Marzipan on Twitter
Analysis thread on Twitter Placental abnormalities in #SarsCov19 infection were associated with significant higher incidence of unexplained stillbirths, and lower Apgar scores.
The placental pathology in #Covid19 infected mothers and its impact on pregnancy outcome…
#COVIDinpregnancy #CovidIsNotOver
Study finds COVID associated with abnormal placental pathologies in nearly 50% of cohort
Taken together, 50% of the study participants’ placentae exhibited abnormal morphologic features. Furthermore, pregnant women with COVID-19 and abnormal placental morphologies were associated with poor pregnancy outcomes
Coronavirus in late pregnancy raises premature birth risk seven-fold
Testing positive for covid-19 after 34 weeks of pregnancy has been linked with a seven-fold higher risk of giving birth prematurely
Bean & Sprout's Mom on Twitter
Fetal lung volume significantly reduced in pregnant women who had #COVID19. Reduced to 69% if first trimester infection, to 91% if third trimester infection.
Fulltext
In pregnant women who tested positive for SARS-CoV-2, normalised fetal lung volume was significantly reduced compared with age-adjusted reference values,4 in the absence of structural abnormalities or organ infarction, and was unexplained by differences in somatic growth (84% vs 24% of 50th percentile reference; p<0·0001; figure). The timepoint of infection showed significant effects on fetal lung growth, with reduced lung volumes observed with SARS-CoV-2 infections acquired during the third trimester (69% vs 91% of 50th percentile reference in the first or second trimester;