Effects of SARS-CoV-2 on prenatal lung growth assessed by fetal MRI
Effects of SARS-CoV-2 on prenatal lung growth assessed by fetal MRI
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Fetal lung volume significantly reduced in pregnant women who had #COVID19. Reduced to 69% if first trimester infection, to 91% if third trimester infection.
Fulltext
In pregnant women who tested positive for SARS-CoV-2, normalised fetal lung volume was significantly reduced compared with age-adjusted reference values,4 in the absence of structural abnormalities or organ infarction, and was unexplained by differences in somatic growth (84% vs 24% of 50th percentile reference; p<0·0001; figure). The timepoint of infection showed significant effects on fetal lung growth, with reduced lung volumes observed with SARS-CoV-2 infections acquired during the third trimester (69% vs 91% of 50th percentile reference in the first or second trimester;