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SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients
SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients
“Patients with COVID-19 may develop abnormal inflammatory response, followed in some cases by severe disease and long-lasting syndromes. We show here that in vitro exposure to SARS-CoV-2 activates the expression of the human endogenous retrovirus (HERV) HERV-W proinflammatory envelope protein (ENV) in peripheral blood mononuclear cells from a subset of healthy donors, in ACE2 receptor and infection-independent manner.”
·flip.it·
SARS-CoV-2 awakens ancient retroviral genes and the expression of proinflammatory HERV-W envelope protein in COVID-19 patients
I checked labs on a young patient this am who I suspected was immune damaged after the last five years
I checked labs on a young patient this am who I suspected was immune damaged after the last five years

“I checked labs on a young patient this am who I suspected was immune damaged after the last five years

His immune cells looked like it was HIV/AIDS, yet he was HIV negative

I am doing this weekly. No other doctor in the hospital is checking

This is why I sounded the alarm a few weeks ago

PCPs must brush up on immunology”

·x.com·
I checked labs on a young patient this am who I suspected was immune damaged after the last five years
Frontiers | Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection
Frontiers | Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection
New research shows SARS2 reinfection doesn’t “boost” your immunity - it narrows it. Each infection further imprints and restricts your T-cell diversity, making your immune response less adaptable over time.
·frontiersin.org·
Frontiers | Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection
Frontiers | Immune cell communication networks and memory CD8+ T cell signatures sustaining chronic inflammation in COVID-19 and Long COVID
Frontiers | Immune cell communication networks and memory CD8+ T cell signatures sustaining chronic inflammation in COVID-19 and Long COVID

Researchers analyzed 73,000 immune cells from COVID-19 patients.

They found that memory CD8+ T cells stay overactive and exhausted long after infection, keeping the immune system in a low-grade inflammatory state that may drive Long COVID.

·frontiersin.org·
Frontiers | Immune cell communication networks and memory CD8+ T cell signatures sustaining chronic inflammation in COVID-19 and Long COVID
Thread by @AbudBakri on Thread Reader App
Thread by @AbudBakri on Thread Reader App

“You’re going to see a lot of immune failure and weird infections in young people over the next 5-10 years

It will start to pickup significantly in 2026”

You’re going to see a lot of immune failure and weird infections in young people over the next 5-10 years It will start to pickup significantly in 2026
·threadreaderapp.com·
Thread by @AbudBakri on Thread Reader App
Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases
Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases

SARS-COV2 COVID at least temporarily causes lymphocytopenia (including T cells) immune suppression. The virus has been found to infect CD8 T cells. HIV AIDS is typically defined by CD4 T cell destruction. This study found COVID infected CD8 T cells.

·pmc.ncbi.nlm.nih.gov·
Postacute COVID-19 is Characterized by Gut Viral Antigen Persistence in Inflammatory Bowel Diseases
Why scientists are rethinking the immune effects of SARS-CoV-2
Why scientists are rethinking the immune effects of SARS-CoV-2

Covid weakens your immune system. You are less likely to fight off pathogens and that is why you are “always sick”. '“There has definitely been a change in the character of the immune response since 2019,” says Tim Henrich, immunologist and senior author of the study. “It’s certainly impacting our immune health, and probably our overall health as well.”'

·bmj.com·
Why scientists are rethinking the immune effects of SARS-CoV-2
emClinical & Translational Immunology/em | ASI Journal | Wiley Online Library
emClinical & Translational Immunology/em | ASI Journal | Wiley Online Library
“In conclusion, our findings demonstrate that immunomodulatory changes in both myeloid and lymphoid cells can persist for up to 17 months following COVID-19, even in individuals who experienced only MILD illness.”m
·onlinelibrary.wiley.com·
emClinical & Translational Immunology/em | ASI Journal | Wiley Online Library
Comprehensive molecular characterization of post-COVID condition: immunoglobulin suppression and persistent SARS-CoV-2 antigens as key pathophysiological drivers
Comprehensive molecular characterization of post-COVID condition: immunoglobulin suppression and persistent SARS-CoV-2 antigens as key pathophysiological drivers
Study analyzed blood from 65 Long COVID patients & found reduced immunoglobulin levels and persistent SARS‑CoV‑2 antigens (spike and nucleocapsid proteins). They used targeted mass spectrometry to measure SARS‑CoV‑2 spike & nucleocapsid proteins in plasma specifically
·sciencedirect.com·
Comprehensive molecular characterization of post-COVID condition: immunoglobulin suppression and persistent SARS-CoV-2 antigens as key pathophysiological drivers
Research: COVID Virus Turns Fighters Into Suppressors
Research: COVID Virus Turns Fighters Into Suppressors
New research from Johns Hopkins finds that white blood cells may be altered by SARS2 to cease their normal function of destroying pathogens in the body and, instead, significantly inhibit other immune cells critical for fighting the virus
·miragenews.com·
Research: COVID Virus Turns Fighters Into Suppressors
Quarterly epidemiological commentary: mandatory Gram-negative bacteraemia, MRSA, MSSA and C. difficile infections (data up to October to December 2024)
Quarterly epidemiological commentary: mandatory Gram-negative bacteraemia, MRSA, MSSA and C. difficile infections (data up to October to December 2024)
Here's really strong evidence of immune damage from COVID among bacterial infections with no vaccines. Look at the sharp climbs in all since 2020.
·gov.uk·
Quarterly epidemiological commentary: mandatory Gram-negative bacteraemia, MRSA, MSSA and C. difficile infections (data up to October to December 2024)
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19
A study new finds that neutrophils—the most abundant white blood cells in humans—may be altered by SARS-CoV-2 virus to cease their normal function of destroying pathogens in the body and, instead, significantly inhibit other immune cells critical for fighting the virus.
·science.org·
SARS-CoV-2 induces neutrophil degranulation and differentiation into myeloid-derived suppressor cells associated with severe COVID-19
The Proof of Immune Harm Is In The Pudding
The Proof of Immune Harm Is In The Pudding
“Nevertheless, we know how covid harms the immune system to the extent to have predicted the immune harm, to the surprise of everyone who believed it was like the common cold or influenza.”
Nevertheless, we know how covid harms the immune system to the extent to have predicted the immune harm, to the surprise of everyone who believed it was like the common cold or influenza.
·easychair.info·
The Proof of Immune Harm Is In The Pudding