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Prior human endemic coronavirus exposure does not affect humoral responses to SARS-CoV-2 protein vaccines
Prior human endemic coronavirus exposure does not affect humoral responses to SARS-CoV-2 protein vaccines
“We included measurement of pre-existing immunity to human endemic coronaviruses (HCoV) in a Phase I/II study of SARS-CoV-2 spike protein vaccine candidates. A Binding Antibody Multiplex Assay measured HCoV-specific IgG to the receptor binding domain or full-length spike of human coronaviruses HKU1, 229E, NL63, and OC43. We found no evidence for the impact of HCoV antibodies on neutralizing and binding antibody responses to the candidate SARS-CoV-2 vaccines.”
#Immune system#antibodies#vaccine#antigenic imprinting#immune system
·flip.it·
Prior human endemic coronavirus exposure does not affect humoral responses to SARS-CoV-2 protein vaccines
Study says original COVID-19 vaccination did not stop immune system from fighting variants
Study says original COVID-19 vaccination did not stop immune system from fighting variants
“Prior COVID-19 vaccination did not stop the immune system from mounting a protective response to the Delta and Omicron strains, though new mutation-specific antibody production dipped slightly, according to a study led by researchers at the University of Arizona Health Sciences and published in Nature Immunology.”
#Immune system#vaccine#antibodies#variants#Delta#Omicron#protective response#mutation-specific antibody
·flip.it·
Study says original COVID-19 vaccination did not stop immune system from fighting variants
Our Immune Systems Blanket the SARS-CoV-2 Spike Protein with Antibodies
Our Immune Systems Blanket the SARS-CoV-2 Spike Protein with Antibodies

This is from 2021. We never heard about it again.

“As part of a new study on hybrid immunity to the virus, the large, multi-institution research team led by The University of Texas at Austin discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient. Using technology developed over several years of research into antibody response, the team led by UT engineers and scientists obtained the exact molecular sequence of the antibody, opening the possibility of manufacturing it on a larger scale for future treatments.”

#SC27#antibodies#treatment#Immune system
·news.utexas.edu·
Our Immune Systems Blanket the SARS-CoV-2 Spike Protein with Antibodies