Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes
COVID’S EFFECT ON THE IMMUNE SYSTEM
“This is an excellent series of graphics from @YaleSPH explaining what we do (and don’t) know about Covid’s effect on the immune system.
Much of this is informed by the work of Dr. Akiko Iwasaki (@VirusesImmunity).”
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19
Study in the US followed 1,154 hospitalized COVID-19 patients for 12 months.
It found reactivation of latent viruses like EBV and CMV during acute COVID-19.
Persistent reactivation of certain viruses correlated with Long COVID symptoms.
Coronavirus Disease 2019 and Mycobacterium tuberculosis... : Journal of Preventive, Diagnostic and Treatment Strategies in Medicine
“the COVID-19 pandemic may lead to a spike in the incidence of active TB.”tuber
the COVID-19 pandemic may lead to a spike in the incidence of active TB.
This is the 5th year of the pandemic in the Let It Rip Kingdom of Sweden. Everyone is constantly reinfected with the immune damaging SARS-CoV-2.
“This is the 5th year of the pandemic in the Let It Rip Kingdom of Sweden. Everyone is constantly reinfected with the immune damaging SARS-CoV-2.
Respiratory virus/bacteria infections like Rhino/Enterovirus, Adenovirus, Mycoplasma pneumoniae or Pertussis are skyrocketing.
🧵1/“
SARS-CoV-2 and Mycobacterium tuberculosis co-infection in vitro
CO-INFECTION is the NEXT TIME BOMB 💥
SARS-CoV-2 + MYCOBACTERIUM TUBERCULOSIS (Mtb), Mtb which was before the pandemic, the leading infectious cause of death worldwide due to a single infectious agent
Hey folks, ONE QUARTER of the global population (1.7 BILLION) carries the bacteria that causes tuberculosis (TB), Mycobacterium tuberculosis, in a dormant state. All it takes to activate lowered immune functioning SARS2.
“Hey folks, ONE QUARTER of the global population (1.7 BILLION) carries the bacteria that causes tuberculosis (TB), Mycobacterium tuberculosis, in a dormant state. All it takes to activate >>> lowered immune functioning >>> SARS2.
Get it now?”
This is the
exactly.
This is the #Leonardi_Effect
This is exactly what @NjbBari3 and I have been saying for 3 years.
A sustained CD 4 count of <500 will get you there. That's data from HIV positive people.
@dbdugger has the receipts. He too has been warning of this inevitably.
Kansas COVID-19 spike coincides with unexplained tuberculosis infections • Kansas Reflector
This is a direct result of immune suppression due to Covid infection. HIV does the same thing.
“As the Kansas and Missouri medical communities prepare for respiratory illness season, health officials grapple with an early COVID-19 infection spike and higher-than-normal tuberculosis infections in Wyandotte County.”
Tuberculosis in individuals who recovered from COVID-19: A systematic review of case reports | PLOS ONE
“Conclusion Tuberculosis after recovering from COVID-19 is becoming more common, potentially leading to a TB outbreak in the post-COVID-19 era. The immunosuppressive nature of the disease and its treatment modalities may contribute to post COVID-19 TB.”
John Hess MD on Twitter
Case Study: 62 healthy, HIV neg. COVID 3/28/23 fully vaccinated, mild symptoms which resolved within a week. Since then 2 cases of shingles, sinusitis and periorbital cellulitis. CD4 297. <200 is AIDS It's not every patient or every infection but it's more common than people want to believe
Accelerated T-Cell Immunosenescence in Cytomegalovirus-Seropositive Individuals After Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Accelerated T-Cell Immunosenescence in Cytomegalovirus-Seropositive Individuals After Severe Acute Respiratory Syndrome Coronavirus 2 Infection
I've had COVID and am constantly getting colds. Did COVID harm my immune system? Am I now at risk of other infectious diseases?
From Sept. 2022: "...what impacts has COVID had on your overall immune system?
It’s early days yet. But growing evidence suggests there are changes to your immune system that may put you at risk of other infectious diseases.
Here’s what we know so far:
COVID-19 Impairs Immune Response to Candida albicans
COVID-19 Impairs Immune Response to Candida albicans
Immune systems seriously weakened by COVID
"...at least three studies show COVID-19 actually kills off a significant number of the body’s T-cells, so even when a someone recovers from COVID, they are at a heightened risk for other viral, bacterial and fungal infections."
SharonBC,Canada on Twitter
Part 1 of 2 A study which supports the theory of Immune DisRegulation. Dr Zacharey Rubin is a paediatric allergist and immunologist. He is on TikTok as @ rubin_allergy.
Had one infection after another this year? There are good reasons why many of us keep getting sick
Australian immunologists discuss the impact of COVID-19 on the immune system, and how this could worsen future risk for other infections.
It has to do with altered function or reprogramming of immune cells, rather than depleted numbers.
Colin Furness MISt PhD MPH on Twitter
Detailed analysis thread on Twitter: What do we have today? A ton of unexplained child illness in the first cold/flu season since we let COVID rip. Hmm.
We have known since 2020 that COVID harms interferon production, a protein that your cells release to call the immune system for help when they are attacked.
‘Immunity debt’: Why experts say this new term promotes COVID-19 ‘misinformation’ - National | Globalnews.ca
So why are so many kids experiencing severe illness from seasonal viruses?
Emerging evidence suggests COVID-19 may be to blame
%2Fcloudfront-us-east-1.images.arcpublishing.com%2Ftgam%2FTRSSNP4T7NJRPH3LYXL2XTRNFA.JPG?width=350&height=&ar=16:9&mode=crop&format=avif&dpr=2)
Opinion: Kids are suffering from COVID in ways we never expected
"What we are likely seeing, he says, is “immunity robbery,” where COVID infection stealthily hobbles the immune system, even in those who don’t suffer severe illness, like many children."
How the Coronavirus Short-Circuits the Immune System (Published 2020)
How the Coronavirus Short-Circuits the Immune System (2020)
Covid flu rsv viruses
"Covid is making flu and other viruses act in unpredictable ways."
Do you keep getting colds after COVID? Here's what we know about how COVID changes your immune system
"I've had COVID and am constantly getting colds. Did COVID harm my immune system? Am I now at risk of other infectious diseases?"
Viral infections like RSV, the flu, and COVID have one Southern California county declaring a pediatric health emergency. It’s far from alone
“Most kids have had COVID, and there could really be something about COVID affecting children’s immune systems that we haven’t been able to fully understand at this time,” she said.
Anthony J Leonardi, MBBS, PhD on Twitter
Looks like after SARS cov 2 infection the risk of other viral infection Quadrupled
dr jack lambert on Twitter
I do lymphocyte subsets on all long covid when possible. Many have low cd4 lymphocytes just like hiv.. I have documented reactivation of cmv. Ebv zoster. This is scarily similar to hiv induced immunosuppressive
Beneficial Immune Regulation by Biological Response Modifier Glucans in COVID-19 and Their Envisaged Potentials in the Management of Sepsis
".. COVID-19-induced organ damage and death are due to immunosuppression, especially CD4+ and CD8+ T-cell lymphopenia. This lymphopenia is.. leading to increased secondary infections.. it is clear that COVID-19 closely resembles sepsis.."
laurie allee on Twitter
Starting thread on increased susceptibility to other infections / opportunistic infections / flares of chronic infections after acute SarsCov2. (Adding to thread started below. Some if this is cross-listed in my threads on T-cells and immune system damage.)