“Immune Parallels: HIV/AIDS & Long COVID’s Lasting Impact
HIV/AIDS & COVID-19, particularly long COVID, share several significant similarities, especially in terms of viral persistence, T cell damage, immune system dysfunction, & activation of other pathogens. These parallels are important for understanding the long-term effects of both infections and their impact on the immune system…” A thread:
T cell exhaustion in #MECFS & #LongCovid from predominant sympathetic state & the T cells engage the sympathetic fibers & adrenergic signaling decreases their effector function. Sympathetic nerves suppress T-cell responses in infection and in cancer
Detailed analysis on Twitter: "As of now, people choose whether or not they have Long Covid based upon their symptoms
However, if most people, after mild infection have changes to their immune systems like reductions in plasmacytoid dendritic cells, without reporting symptoms, what should this be called?"
Medical anecdote: I'm no immunologist but a CD4 count < 500 increases your risk of opportunistic infections. At only 317, you're certainly immunocompromised. I'm so sorry; this is highly disturbing. Lymphocyte Subset panels should be ordered for all Long Covid sufferers.