How (multiple) COVID infections impact your immune system
Long lived antibodies can be made in the bone marrow, the holy grail of vaccination. This is what happens after different time intervals after flu, tetanus and mRNA Covid vaccines. The box in purple is SARS-CoV-2 in the bone marrow. At months 2.5 and 14 they are empty.🧵
“SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination”
SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination
“SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination”
I've had COVID and am constantly getting colds. Did COVID harm my immune system? Am I now at risk of other infectious diseases?
From Sept. 2022: "...what impacts has COVID had on your overall immune system?
It’s early days yet. But growing evidence suggests there are changes to your immune system that may put you at risk of other infectious diseases.
Here’s what we know so far:
laurie allee on Twitter
"The fact that they saw dramatically lower CD8 or killer T cell responses than everyone else indicated that there was some damage—something was happening after the infection in these people.”
Getting COVID-19 Could Weaken Your Immune System
"Even relatively easy bouts with COVID-19 can still take a toll on the immune system, according to a paper published Mar. 15 in the journal Immunity—particularly on T-cells, which provide long term and durable protection against viruses."
COVID-19 Impairs Immune Response to Candida albicans
COVID-19 Impairs Immune Response to Candida albicans
Immune systems seriously weakened by COVID
"...at least three studies show COVID-19 actually kills off a significant number of the body’s T-cells, so even when a someone recovers from COVID, they are at a heightened risk for other viral, bacterial and fungal infections."
SharonBC,Canada on Twitter
Part 1 of 2 A study which supports the theory of Immune DisRegulation. Dr Zacharey Rubin is a paediatric allergist and immunologist. He is on TikTok as @ rubin_allergy.
Had one infection after another this year? There are good reasons why many of us keep getting sick
Australian immunologists discuss the impact of COVID-19 on the immune system, and how this could worsen future risk for other infections.
It has to do with altered function or reprogramming of immune cells, rather than depleted numbers.
Colin Furness MISt PhD MPH on Twitter
Detailed analysis thread on Twitter: What do we have today? A ton of unexplained child illness in the first cold/flu season since we let COVID rip. Hmm.
We have known since 2020 that COVID harms interferon production, a protein that your cells release to call the immune system for help when they are attacked.
‘Immunity debt’: Why experts say this new term promotes COVID-19 ‘misinformation’ - National | Globalnews.ca
So why are so many kids experiencing severe illness from seasonal viruses?
Emerging evidence suggests COVID-19 may be to blame
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Opinion: Kids are suffering from COVID in ways we never expected
"What we are likely seeing, he says, is “immunity robbery,” where COVID infection stealthily hobbles the immune system, even in those who don’t suffer severe illness, like many children."
What If COVID Reinfections Wear Down Our Immunity? | The Tyee
But what if COVID wears down T cells in people who get it, and does so increasingly with each reinfection?
How the Coronavirus Short-Circuits the Immune System (Published 2020)
How the Coronavirus Short-Circuits the Immune System (2020)
Covid flu rsv viruses
"Covid is making flu and other viruses act in unpredictable ways."
Do you keep getting colds after COVID? Here's what we know about how COVID changes your immune system
"I've had COVID and am constantly getting colds. Did COVID harm my immune system? Am I now at risk of other infectious diseases?"
Viral infections like RSV, the flu, and COVID have one Southern California county declaring a pediatric health emergency. It’s far from alone
“Most kids have had COVID, and there could really be something about COVID affecting children’s immune systems that we haven’t been able to fully understand at this time,” she said.
Anthony J Leonardi, MBBS, PhD on Twitter
Looks like after SARS cov 2 infection the risk of other viral infection Quadrupled
Evidence brief ba4 ba5 risk assessment jul 8
"Evidence shows that SARS-CoV-2 reinfection adds risk of all-cause mortality, hospitalization and adverse health outcomes during acute and post-acute SARS-CoV-2 reinfection, and that the risk and burden may increase in a graded manner according to the number of infections. The evidence that SARS-CoV-2 can cause immune dysregulation is increasing."
Chris Turnbull on Twitter
Detailed analysis on Twitter: Covid, Sars 2: Public Health Canada finally admits and warns about 'immune dysregulation' caused by the virus which could have 'significant impact on the incidence and associated burden of infectious diseases' in latest briefing and that reinfection increases chances of death