“In the blood of the long COVID patients, the team [at the University of Alberta] found higher levels of various proteins related to systemic inflammation—especially galectin-9 and artemin.. higher levels of galectin-9 in patients are associated with increased inflammation and brain fog.. higher levels of artemin are associated with widespread pain, more severe pain and cognitive impairment.. galectin-9 is shed by stressed neutrophils—the most abundant white blood cells—in long COVID patients. This released galectin-9 can promote chronic inflammation by affecting various immune cells.. long COVID dysregulates the production of red blood cells, which results in an abundance of immature red blood cells in the blood of these patients. Normally, immature red blood cells are present in the bone marrow but not in the blood of healthy people. It is these immature red blood cells in the blood that suppress the immune system and contribute to the elevation of artemin in the plasma of long-COVID patients."
“This is the 5th year of the pandemic in the Let It Rip Kingdom of Sweden. Everyone is constantly reinfected with the immune damaging SARS-CoV-2.
Respiratory virus/bacteria infections like Rhino/Enterovirus, Adenovirus, Mycoplasma pneumoniae or Pertussis are skyrocketing.
🧵1/“
“An important paper!
We keep focusing on Spike protein-only vaccines -> to our peril
It’s the 1 protein w the #1 MOST reasons to mutate!
Many parts of the virus also drive robust immune protection
Tmrws vaccines should focus on non-Spike to reduce variant immune evasion”
“Long COVID’ affects nearly one in five adults who have had coronavirus disease 2019 (COVID-19), yet the mechanisms underlying this disorder remain poorly understood. In a new study, Cheong et al. show that the epigenetic and transcriptional state of myeloid immune cells and their progenitors are durably altered in patients following severe COVID-19.”
“Long COVID, or post-acute COVID syndrome (PACS), is now estimated to occur in 19% of adults having presented with COVID-19.. PACS is believed to be caused by immunological changes that persist after acute infection. Furthermore, it is now increasingly recognized that these changes include not only those in the adaptive immune system, such as production of autoantibodies or autoreactive T cells due to molecular mimicry, but also those in the innate immune system.. A new study by Cheong et al. in Cell reveals crucial differences in the transcriptional and epigenetic state of innate immune cells and their progenitors [among PASC patients].. the study team demonstrated that myeloid cells and hematopoietic progenitor cells harbored transcriptional and chromatin accessibility changes that did not return to baseline even 1 year after acute SARS-CoV-2 infection. These data provide powerful evidence that persistent changes (i.e., trained immunity) may underlie PACS..”
“Man given 12 months to live after headaches. It's glioblastoma.
@nypost will never share that CMV is airborne and causes glioblastoma.
90% of us have CMV. COVID dysregulates the immune system. So does CMV when reactivated.
COVID can reactivate CMV.”
“In a recent interview, Fauci puts the C19 herd immunity fantasy to bed once and for all. No such thing can ever be achieved, due to lack of immune response durability”
“There's a lot you can do to boost your immune system.
Getting sick isn't one of them.”
COVID more severe, longer-lasting than other respiratory diseases.
The findings support the histopathological evidence of an exuberant immune reaction associated with SARS-CoV-2 infection.
This is from 2021. We never heard about it again.
“As part of a new study on hybrid immunity to the virus, the large, multi-institution research team led by The University of Texas at Austin discovered and isolated a broadly neutralizing plasma antibody, called SC27, from a single patient. Using technology developed over several years of research into antibody response, the team led by UT engineers and scientists obtained the exact molecular sequence of the antibody, opening the possibility of manufacturing it on a larger scale for future treatments.”
Your immune system is a factory 🧵
T-cells are the essential workers.
SARS-CoV-2 -19 is a hacker that doesn't just disrupt operations from the outside.
It infiltrates the system and systematically lays off the workers (T-cells).
CO-INFECTION is the NEXT TIME BOMB 💥
SARS-CoV-2 + MYCOBACTERIUM TUBERCULOSIS (Mtb), Mtb which was before the pandemic, the leading infectious cause of death worldwide due to a single infectious agent
“Hey folks, ONE QUARTER of the global population (1.7 BILLION) carries the bacteria that causes tuberculosis (TB), Mycobacterium tuberculosis, in a dormant state. All it takes to activate >>> lowered immune functioning >>> SARS2.
Get it now?”
exactly.
This is the #Leonardi_Effect
This is exactly what @NjbBari3 and I have been saying for 3 years.
A sustained CD 4 count of <500 will get you there. That's data from HIV positive people.
@dbdugger has the receipts. He too has been warning of this inevitably.
This is a direct result of immune suppression due to Covid infection. HIV does the same thing.
“As the Kansas and Missouri medical communities prepare for respiratory illness season, health officials grapple with an early COVID-19 infection spike and higher-than-normal tuberculosis infections in Wyandotte County.”
T cell exhaustion in #MECFS & #LongCovid from predominant sympathetic state & the T cells engage the sympathetic fibers & adrenergic signaling decreases their effector function. Sympathetic nerves suppress T-cell responses in infection and in cancer
"Molecular Trickery: How Covid Silently Sabotages the Human Immune System... Researchers have discovered that SARS-CoV-2 manipulates the human immune system by forcing cells to produce non-functional proteins, hindering the body’s antiviral defenses."
Study from California State University analyzed immune responses to 35 viruses using data from 219 datasets.
Findings show SARS-CoV-2 triggers a unique cytokine-chemokine profile, distinct from other viruses.
Excellent explanation of mechanism discussed in recent SarsCov2 causing AIDS paper.
“So, to recap: Researchers identified two genotypes of the SARS-CoV-2 nucleocapsid protein that are able to use CD147 on host lymphocytes to infect those cells, and explain how that could contribute to immune deficiency and viral persistence (by citing independent research).”
