Covid weakens your immune system. You are less likely to fight off pathogens and that is why you are “always sick”. '“There has definitely been a change in the character of the immune response since 2019,” says Tim Henrich, immunologist and senior author of the study. “It’s certainly impacting our immune health, and probably our overall health as well.”'

Covid and the Immune System
SARS-CoV-2 and HIV-1 both cause CD4⁺ T cell loss, cytokine storms, and immune exhaustion.
Shared mechanisms—like pyroptosis and inhibitory receptor upregulation—suggest overlapping therapeutic targets.
another way Covid weakens our interferon responses so it can invade our brains:
Variants with nsp15 endoribonuclease activity exhibit stronger replication in the respiratory tract, enabling neuroinvasion and causing more severe disease.
“COVID-19 disrupts immune system function, leading to both acute damage and long-term dysregulation.
The infection is associated with severe lymphopenia, particularly affecting T cells and natural killer cells, which can persist long after recovery.”
“I’ve been accused of being ‘hyperbolic’ for comparing Covid to AIDS. So let’s talk immune damage. With citations. 🧵”
Diagnostic Criteria for MCAS activated by LongCOVID & Post-Vaccination Syndrome PVS
New study shows that SARS-CoV2 Spike Proteins induces Mast Cell Activation and MCAS
How COVID dysregulates the immune system and affects blood vessels * CBC interview with Dr David Putrino of Mt Sinai Long COVID Clinic
Covid and the immune system
A large-scale sample of Covid survivors and controls with a negative Covid test, showed Covid survivors were more prone to infections like bacterial infections and herpesviruses reactivation in the 12 month post Covid