Victim Has Immune Depletion & Opportunistic Fungal Infection:
To everyone who said "There's no way Long C*vid is like HIV. That's an unhelpful exaggeration." Cool. Please tell that to my negligible immunoglobulins...
Covid and the Immune System
Four lessons COVID taught us about the immune system
“Four lessons COVID taught us about the immune system”
Four lessons COVID taught us about the immune system
NK Cell-Monocyte Cross-talk Underlies NK Cell Activation in Severe COVID-19 - PubMed
Here is a hypothesis that Covid harms NK cells
These cells kill circulating cancer cells and precancerous cells
NK dysfunction limit immune system control of precancer and cancer cells.
Doctors from Texas Warn That Post COVID-19 Individuals Are More Susceptible to Coccidioidomycosis Infections - Thailand Medical News
Doctors from Texas Warn That Post COVID-19 Individuals Are More Susceptible to Coccidioidomycosis Infections
SARS-CoV-2 uses CD4 to infect T helper lymphocytes
SARS-CoV-2 infects human CD4+ T helper cells by binding its spike glycoprotein to the CD4 molecule, impairing cell function and potentially causing cell death.
This mechanism involves the interaction of the virus with both CD4 and ACE2 receptors.
Immune dysregulation in long COVID patients uncovered in new study
“The results showed that compared to COVID-19 patients who had fully recovered, long COVID patients showed evidence of immune dysregulation and systemic inflammation, with the distribution of T cells exhibiting global differences indicative of continued immune responses.”
The results showed that compared to COVID-19 patients who had fully recovered, long COVID patients showed evidence of immune dysregulation and systemic inflammation, with the distribution of T cells exhibiting global differences indicative of continued immune responses.
COVID-19 leads to long-term changes in the immune system, study shows
This is why there are so many pathogens repeatedly circulating in ways we didn’t see before Covid.
Immune systems can’t fight off the bugs because SarsCov2 damages the immune system.
“COVID-19 leads to considerable long-term changes in the immune system, even in mild cases. The findings could help to better understand the long-term consequences of an infection with SARS-CoV-2.”
COVID-19 leads to considerable long-term changes in the immune system, even in mild cases. The findings could help to better understand the long-term consequences of an infection with SARS-CoV-2.
According to a NEW study, post COVID–19 patients showed immune dysregulation regardless of disease severity characterized mainly by altered expression of activation and functional markers in myeloid (CD39, CD64, CD85d, CD11b) and lymphoid cells (CD39, CD57, TIGIT). 1/
“According to a NEW study, post COVID–19 patients showed immune dysregulation regardless of disease severity characterized mainly by altered expression of activation and functional markers in myeloid (CD39, CD64, CD85d, CD11b) and lymphoid cells (CD39, CD57, TIGIT)”
In this first of the 2 part series of BBC Science in Action - 5 years of COVID, I discuss the importance of studying the immune responses to SARS-CoV-2 and mucosal vaccines with . With and others 👇🏼
“In this first of the 2 part series of BBC Science in Action - 5 years of COVID, I discuss the importance of studying the immune responses to SARS-CoV-2 and mucosal vaccines with @PeaseRoland. With @MarionKoopmans @c_drosten @dtsh2 and others 👇🏼”
Health workers are seeing a rise in shingles. COVID might be part of the reason why
“Shingles cases are increasing in New South Wales. Experts say COVID might be why”
Shingles cases are increasing in New South Wales. Experts say COVID might be why
Imagine, in the 1980s...
“Imagine, in the 1980s...
‘I finally got HIV - just in time for Christmas. And I couldn't be happier. Here's why.’
Think that's a stretch? Covid is sparking what were once AIDS-defining conditions. It's disastrous for the immune system. And every other organ/system of the body.”
Surge of mucormycosis during the COVID-19 pandemic
Mucormycosis is a flesh eating fungus, nearly impossible to treat.
Virtually never seen in the immunocompetent........ Until 2022-Present
Study: COVID can trigger changes to the immune system that may underlie persistent symptoms | CIDRAP
“Study: COVID can trigger changes to the immune system that may underlie persistent symptoms”
Acquired Immune Deficiency Syndrome correlation with SARS-CoV-2 N genotypes
How (multiple) COVID infections impact your immune system
Researchers discover new cause of cytokine storm in COVID-19
“RAAS, a hormone system that normally turns on and off to help regulate blood pressure, body fluids and electrolytes, is the spark that pushes the immune response into overdrive.”
Research Reveals COVID-19's Body-Wide Impact
“Notably, we also found that activation of RAAS caused substantial damage to the lymph nodes, which hasn't been shown in COVID-19 before," said Beheshti, who is also director of McGowan's Center for Space Biomedicine . "This could explain the long-lasting immune dysregulation seen in survivors of COVID-19 and may contribute to long COVID."
It's also possible that damage to lymph nodes could impair the immune system's ability to detect and destroy cancerous cells, which could potentially help explain the post-pandemic increase in cancer cases.”
Notably, we also found that activation of RAAS caused substantial damage to the lymph nodes, which hasn't been shown in COVID-19 before," said Beheshti, who is also director of McGowan's Center for Space Biomedicine . "This could explain the long-lasting immune dysregulation seen in survivors of COVID-19 and may contribute to long COVID."It's also possible that damage to lymph nodes could impair the immune system's ability to detect and destroy cancerous cells, which could potentially help explain the post-pandemic increase in cancer cases.
COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation
“COVID-19 progression and convalescence in common variable immunodeficiency patients show dysregulated adaptive immune responses and persistent type I interferon and inflammasome activation.
…Our results show a broad dysregulation of both the innate and the adaptive immunity systems during SARS-CoV-2 infection and subsequent recovery in CVID patients, which gives us a unique insight into the effects of a viral challenge on the different immune cells”
The identification of a SARs-CoV2 S1 protein derived peptide with super-antigen-like stimulatory properties on T-cells
A peptide derived from the SARS-CoV-2 S1 spike protein, named P3, can stimulate a significant portion of human T cells.
This stimulation leads to increased production of inflammatory cytokines and granzyme B.
How the XEC Variant Pushes the Boundaries of Immune Evasion—and What It Means for Our Health
“The recently published study on the XEC variant (November 22, 2024) provides fresh insights into how this virus is evolving. (1) Combining this with the broader history of immune evasion, we see a troubling pattern: the virus continues to find ways to evade the immune system and in many cases, persist, potentially leaving lasting impacts on our health even for those who experience only mild or asymptomatic infections.”
COVID’S EFFECT ON THE IMMUNE SYSTEM
“This is an excellent series of graphics from @YaleSPH explaining what we do (and don’t) know about Covid’s effect on the immune system.
Much of this is informed by the work of Dr. Akiko Iwasaki (@VirusesImmunity).”
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
“Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2”
Long COVID manifests with T cell dysregulation, inflammation and an uncoordinated adaptive immune response to SARS-CoV-2
SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses
SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses
SARS-CoV-2 hijacks cholesterol trafficking to fuel infection and evade immune responses
Part 1 of 2
“Part 1 of 2 LaughterinLight PhD is a biomedical researcher, immunologist
- Answering: Can you explain the difference between how COVID affects your immune system vs how HIV affects it? * Feb 2024”
Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19
Study in the US followed 1,154 hospitalized COVID-19 patients for 12 months.
It found reactivation of latent viruses like EBV and CMV during acute COVID-19.
Persistent reactivation of certain viruses correlated with Long COVID symptoms.
This is what a yeast infection in your blood looks like under the microscope. I don't have to tell you how bad this is. As more & more people are repeatedly infected by SARS-CoV-2, wreaking havoc on their immune systems, we will see more & more of these type of infections. 🚫🦠😷
“This is what a yeast infection in your blood looks like under the microscope. I don't have to tell you how bad this is. As more & more people are repeatedly infected by SARS-CoV-2, wreaking havoc on their immune systems, we will see more & more of these type of infections.”
Looks like Yale school of public health has finally started to say what I have been repeatedly saying since 2020
“Looks like Yale school of public health has finally started to say what I have been repeatedly saying since 2020
1) covid creates longlasting autoimmunity by harming t regs 2) harms adaptive immunity 3) causes immune dysregulation 4) persists etc”
Frontiers | Cytokine Storm in COVID-19: The Current Evidence and Treatment Strategies
COVID-19 can cause a severe immune response known as a cytokine storm, leading to poor prognosis and potentially fatal outcomes.
The virus triggers excessive infiltration of immune cells, such as macrophages and T-helper 17 cells.
SARS-CoV-2 can trigger an overactive immune response, leading to the release of large amounts of pro-inflammatory cytokines.
“SARS-CoV-2 can trigger an overactive immune response, leading to the release of large amounts of pro-inflammatory cytokines.
This excessive cytokine release can cause widespread inflammation, leading to damage in various organs, including the lungs, heart, and kidneys.”
SARS-CoV-2 'steals' our proteins to protect itself from the immune system, study reveals
SARS-CoV-2 'steals' our proteins to protect itself from the immune system, study reveals